Discovery of 4-oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-nitrobenzoate (ML221) as a functional antagonist of the apelin (APJ) receptor
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Apelin, Elabela/Toddler, and biased agonists as novel therapeutic agents in the cardiovascular systemRegulation of the Apelinergic System and Its Potential in Cardiovascular Disease: Peptides and Small Molecules as Tools for Discovery.Apelin/APJ system: a promising therapy target for hypertension.Effect of the spinal apelin‑APJ system on the pathogenesis of chronic constriction injury‑induced neuropathic pain in rats.Apelin signaling: new G protein-coupled receptor pathway in lymphatic vascular developmentOpioid receptors mediate inotropic and depressor effects of apelin in rats with 2K1C-induced chronic renovascular hypertension.An apelin receptor antagonist prevents pathological retinal angiogenesis with ischemic retinopathy in mice.A Time-Resolved FRET Cell-Based Binding Assay for the Apelin Receptor.The Role of Apelin in Cardiovascular Diseases, Obesity and Cancer.Apelin Effects Migration and Invasion Abilities of Colon Cancer CellsRepurposing antimalarial aminoquinolines and related compounds for treatment of retinal neovascularization
P2860
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P2860
Discovery of 4-oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-nitrobenzoate (ML221) as a functional antagonist of the apelin (APJ) receptor
description
2012 nî lūn-bûn
@nan
2012年の論文
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2012年学术文章
@wuu
2012年学术文章
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2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
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name
Discovery of 4-oxo-6-
@nl
Discovery of 4-oxo-6-((pyrimid ...... t of the apelin (APJ) receptor
@en
type
label
Discovery of 4-oxo-6-
@nl
Discovery of 4-oxo-6-((pyrimid ...... t of the apelin (APJ) receptor
@en
prefLabel
Discovery of 4-oxo-6-
@nl
Discovery of 4-oxo-6-((pyrimid ...... t of the apelin (APJ) receptor
@en
P2093
P2860
P1476
Discovery of 4-oxo-6-((pyrimid ...... t of the apelin (APJ) receptor
@en
P2093
Alka Mehta
Arianna Mangravita Novo
Derek Stonich
Eduard Sergienko
Eigo Suyama
Eliot Sugarman
Fu-Yue Zeng
Gregory P Roth
Hung Nguyen
Jena Diwan
P2860
P304
P356
10.1016/J.BMCL.2012.08.105
P407
P577
2012-09-07T00:00:00Z