Amino acids 1055 to 1192 in the S2 region of severe acute respiratory syndrome coronavirus S protein induce neutralizing antibodies: implications for the development of vaccines and antiviral agents
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Vaccine efficacy in senescent mice challenged with recombinant SARS-CoV bearing epidemic and zoonotic spike variantsAmino acids 15-28 in the ectodomain of SARS coronavirus 3a protein induces neutralizing antibodies.Adaptive evolution of the spike gene of SARS coronavirus: changes in positively selected sites in different epidemic groupsSubstitution at aspartic acid 1128 in the SARS coronavirus spike glycoprotein mediates escape from a S2 domain-targeting neutralizing monoclonal antibodyA 219-mer CHO-expressing receptor-binding domain of SARS-CoV S protein induces potent immune responses and protective immunitySingle amino acid substitutions in the severe acute respiratory syndrome coronavirus spike glycoprotein determine viral entry and immunogenicity of a major neutralizing domain.The spike protein of SARS-CoV--a target for vaccine and therapeutic development.Monoclonal antibodies targeting the HR2 domain and the region immediately upstream of the HR2 of the S protein neutralize in vitro infection of severe acute respiratory syndrome coronavirus.Human monoclonal antibodies against highly conserved HR1 and HR2 domains of the SARS-CoV spike protein are more broadly neutralizingSynthetic reconstruction of zoonotic and early human severe acute respiratory syndrome coronavirus isolates that produce fatal disease in aged mice.SARS vaccine developmentChimeric coronavirus-like particles carrying severe acute respiratory syndrome coronavirus (SCoV) S protein protect mice against challenge with SCoVImmunogenicity and protection efficacy of monomeric and trimeric recombinant SARS coronavirus spike protein subunit vaccine candidatesPriming with rAAV encoding RBD of SARS-CoV S protein and boosting with RBD-specific peptides for T cell epitopes elevated humoral and cellular immune responses against SARS-CoV infection.Molecular targets for diagnostics and therapeutics of severe acute respiratory syndrome (SARS-CoV).Neutralizing human monoclonal antibodies to severe acute respiratory syndrome coronavirus: target, mechanism of action, and therapeutic potential.SARS-CoV genome polymorphism: a bioinformatics studyQuantitative comparison of the efficiency of antibodies against S1 and S2 subunit of SARS coronavirus spike protein in virus neutralization and blocking of receptor binding: implications for the functional roles of S2 subunit.Antigenic and immunogenic characterization of recombinant baculovirus-expressed severe acute respiratory syndrome coronavirus spike protein: implication for vaccine design.Identification and characterization of a neutralizing-epitope-containing spike protein fragment in turkey coronavirus.
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P2860
Amino acids 1055 to 1192 in the S2 region of severe acute respiratory syndrome coronavirus S protein induce neutralizing antibodies: implications for the development of vaccines and antiviral agents
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
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2005年學術文章
@zh-hant
name
Amino acids 1055 to 1192 in th ...... vaccines and antiviral agents
@en
Amino acids 1055 to 1192 in th ...... vaccines and antiviral agents
@nl
type
label
Amino acids 1055 to 1192 in th ...... vaccines and antiviral agents
@en
Amino acids 1055 to 1192 in th ...... vaccines and antiviral agents
@nl
prefLabel
Amino acids 1055 to 1192 in th ...... vaccines and antiviral agents
@en
Amino acids 1055 to 1192 in th ...... vaccines and antiviral agents
@nl
P2093
P2860
P1433
P1476
Amino acids 1055 to 1192 in th ...... vaccines and antiviral agents
@en
P2093
Aihua Zhang
Burtram C Fielding
Chay Boon Loh
Chih-Fong Chou
Choong-Tat Keng
Jianlin Fu
Kuo-Ming Lip
Seng Gee Lim
Sifang Wang
P2860
P304
P356
10.1128/JVI.79.6.3289-3296.2005
P407
P577
2005-03-01T00:00:00Z