Reduced replication capacity of NL4-3 recombinant viruses encoding reverse transcriptase-integrase sequences from HIV-1 elite controllers. - Wikidata - wikimedia - TriplyDB

Reduced replication capacity of NL4-3 recombinant viruses encoding reverse transcriptase-integrase sequences from HIV-1 elite controllers.

Reduced replication capacity of NL4-3 recombinant viruses encoding reverse transcriptase-integrase sequences from HIV-1 elite controllers.

http://www.wikidata.org/entity/Q42718488

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Role of HLA Adaptation in HIV Evolution Identification of a cluster of HIV-1 controllers infected with low replicating viruses Identification of Immunogenic Cytotoxic T Lymphocyte Epitopes Containing Drug Resistance Mutations in Antiretroviral Treatment-Naïve HIV-Infected Individuals Association of single nucleotide polymorphisms in the lens epithelium-derived growth factor (LEDGF/p75) with HIV-1 infection outcomes in Brazilian HIV-1+ individuals A correlate of HIV-1 control consisting of both innate and adaptive immune parameters best predicts viral load by multivariable analysis in HIV-1 infected viremic controllers and chronically-infected non-controllers Low-replicating viruses and strong anti-viral immune response associated with prolonged disease control in a superinfected HIV-1 LTNP elite controller No evidence for selection of HIV-1 with enhanced gag-protease or Nef function among breakthrough infections in the CAPRISA 004 tenofovir microbicide trial.CD4+ T cells from elite suppressors are more susceptible to HIV-1 but produce fewer virions than cells from chronic progressors.Anti-APOBEC3G activity of HIV-1 Vif protein is attenuated in elite controllers Modest attenuation of HIV-1 Vpu alleles derived from elite controller plasma Screening of the Pan-African natural product library identifies ixoratannin A-2 and boldine as novel HIV-1 inhibitors.Immune-mediated attenuation of HIV-1 Uncommon pathways of immune escape attenuate HIV-1 integrase replication capacity.Consequences of HLA-B*13-Associated Escape Mutations on HIV-1 Replication and Nef Function.Lack of a significant impact of Gag-Protease-mediated HIV-1 replication capacity on clinical parameters in treatment-naive Japanese individuals.Intersubtype differences in the effect of a rare p24 gag mutation on HIV-1 replicative fitness.Population-Level Immune-Mediated Adaptation in HIV-1 Polymerase during the North American Epidemic Host factors dictate control of viral replication in two HIV-1 controller/chronic progressor transmission pairs.Nef Proteins from HIV-1 Elite Controllers Are Inefficient at Preventing Antibody-Dependent Cellular Cytotoxicity HIV-1 conserved-element vaccines: relationship between sequence conservation and replicative capacity Elevated hypermutation levels in HIV-1 natural viral suppressors.Impact of protective killer inhibitory receptor/human leukocyte antigen genotypes on natural killer cell and T-cell function in HIV-1-infected controllers.HLA-B*57 elite suppressor and chronic progressor HIV-1 isolates replicate vigorously and cause CD4+ T cell depletion in humanized BLT mice.Impaired human immunodeficiency virus type 1 replicative fitness in atypical viremic non-progressor individuals.HIV-1 replicative fitness in elite controllers.The implications of viral reservoirs on the elite control of HIV-1 infection.HIV controllers: a genetically determined or inducible phenotype?Unravelling the mechanisms of durable control of HIV-1.Impaired Downregulation of NKG2D Ligands by Nef Proteins from Elite Controllers Sensitizes HIV-1-Infected Cells to Antibody-Dependent Cellular Cytotoxicity.Identification of Interleukin-27 (IL-27)/IL-27 Receptor Subunit Alpha as a Critical Immune Axis for In Vivo HIV Control.Novel Acylguanidine-Based Inhibitor of HIV-1.Accumulation of Pol Mutations Selected by HLA-B*52:01-C*12:02 Protective Haplotype-Restricted Cytotoxic T Lymphocytes Causes Low Plasma Viral Load Due to Low Viral Fitness of Mutant Viruses.Pairwise growth competition assay for determining the replication fitness of human immunodeficiency viruses.Attenuation of multiple Nef functions in HIV-1 elite controllers.Impaired Nef function is associated with early control of HIV-1 viremia.Association of the HLA-B*52 allele with non-progression to AIDS in Brazilian HIV-1-infected individuals.What Is the most Important for Elite Control: Genetic Background of Patient, Genetic Background of Partner, both or neither? Description of Complete Natural History within a Couple of MSM.Understanding the CD8 T-cell response in natural HIV control Pol-Driven Replicative Capacity Impacts Disease Progression in HIV-1 Subtype C Infection

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Reduced replication capacity of NL4-3 recombinant viruses encoding reverse transcriptase-integrase sequences from HIV-1 elite controllers.

http://www.wikidata.org/entity/Q42718488

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2011 nî lūn-bûn

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2011年論文

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2011年論文

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2011年论文

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2011年论文

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Reduced replication capacity o ...... from HIV-1 elite controllers.

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Reduced replication capacity o ...... from HIV-1 elite controllers.

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Reduced replication capacity o ...... from HIV-1 elite controllers.

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Journal of Acquired Immune Deficiency Syndromes

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Reduced replication capacity o ...... from HIV-1 elite controllers.

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Brian L Block

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Carl M Kadie

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Chun Li

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Eric Martin

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Jennifer Sela

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Pamela C Rosato

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Toshiyuki Miura

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Tristan J Markle

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P2860

Variable fitness impact of HIV-1 escape mutations to cytotoxic T lymphocyte (CTL) response

HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors

Statistical significance for genomewide studies

A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood

The influence of HLA genotype on AIDS

HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8(+) T Cell Response against HIV-1.

Transmission of HIV-1 CTL escape variants provides HLA-mismatched recipients with a survival advantage.

Elite suppressor-derived HIV-1 envelope glycoproteins exhibit reduced entry efficiency and kinetics

HLA-associated immune escape pathways in HIV-1 subtype B Gag, Pol and Nef proteins.

A dual infection/competition assay shows a correlation between ex vivo human immunodeficiency virus type 1 fitness and disease progression.

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100-108

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10.1097/QAI.0B013E3181FE9450

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2

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Bruce D. Walker

Chanson J Brumme

Mark A. Brockman

Zabrina L Brumme

Florencia Pereyra

David Heckerman

Alicja Piechocka-Trocha

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2011-02-01T00:00:00Z

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21124229

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3078702

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