A novel spatiotemporal RhoC activation pathway locally regulates cofilin activity at invadopodia. - Wikidata - wikimedia - TriplyDB

A novel spatiotemporal RhoC activation pathway locally regulates cofilin activity at invadopodia.

A novel spatiotemporal RhoC activation pathway locally regulates cofilin activity at invadopodia.

http://www.wikidata.org/entity/Q42721724

about

The dynamics of spatio-temporal Rho GTPase signaling: formation of signaling patterns Post-translational modification-regulated leukocyte adhesion and migration Cell polarity signaling in the plasticity of cancer cell invasiveness Rho GTPase signalling in cell migration Phosphorylation-mediated regulation of GEFs for RhoA The interplay between the proteolytic, invasive, and adhesive domains of invadopodia and their roles in cancer invasion RhoC interacts with integrin α5β1 and enhances its trafficking in migrating pancreatic carcinoma cells Rgnef (p190RhoGEF) knockout inhibits RhoA activity, focal adhesion establishment, and cell motility downstream of integrins A RhoC biosensor reveals differences in the activation kinetics of RhoA and RhoC in migrating cells Podoplanin mediates ECM degradation by squamous carcinoma cells through control of invadopodia stability The RhoGEF TEM4 Regulates Endothelial Cell Migration by Suppressing Actomyosin Contractility Spatiotemporal analysis of RhoA/B/C activation in primary human endothelial cells Tks5 and SHIP2 regulate invadopodium maturation, but not initiation, in breast carcinoma cells Spatiotemporal regulation of Src and its substrates at invadosomes Spatial regulation of RhoC activity defines protrusion formation in migrating cells Transducer of Cdc42-dependent actin assembly promotes breast cancer invasion and metastasis.Cadherin-6B stimulates an epithelial mesenchymal transition and the delamination of cells from the neural ectoderm via LIMK/cofilin mediated non-canonical BMP receptor signaling.Adhesion rings surround invadopodia and promote maturation.Pattern formation of Rho GTPases in single cell wound healing.ARF1 regulates the Rho/MLC pathway to control EGF-dependent breast cancer cell invasion Intravital multiphoton imaging reveals multicellular streaming as a crucial component of in vivo cell migration in human breast tumors Fascin 1 is transiently expressed in mouse melanoblasts during development and promotes migration and proliferation.Macrophage contact induces RhoA GTPase signaling to trigger tumor cell intravasation.Chemotaxis in cancer A Trio-Rac1-Pak1 signalling axis drives invadopodia disassembly.DENND2B activates Rab13 at the leading edge of migrating cells and promotes metastatic behavior.Toward understanding RhoGTPase specificity: structure, function and local activation.Optical Tools To Study the Isoform-Specific Roles of Small GTPases in Immune Cells.High-resolution live-cell imaging and time-lapse microscopy of invadopodium dynamics and tracking analysis.p53 in cell invasion, podosomes, and invadopodia RhoD Inhibits RhoC-ROCK-Dependent Cell Contraction via PAK6.Importance of RhoGTPases in formation, characteristics, and functions of invadosomes.Regulation of invadopodia by the tumor microenvironment.Identification of a novel actin-binding domain within the Rho guanine nucleotide exchange factor TEM4.Rho GTPase expression in human myeloid cells Cofilin activation during podosome belt formation in osteoclasts Podosomes in adhesion, migration, mechanosensing and matrix remodeling.TGF-β2-induced invadosomes in human trabecular meshwork cells Dense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network.Profilin1 regulates invadopodium maturation in human breast cancer cells

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P2860

A novel spatiotemporal RhoC activation pathway locally regulates cofilin activity at invadopodia.

http://www.wikidata.org/entity/Q42721724

description

2011 nî lūn-bûn

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2011年の論文

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年學術文章

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2011年學術文章

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2011年學術文章

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name

A novel spatiotemporal RhoC ac ...... filin activity at invadopodia.

@en

A novel spatiotemporal RhoC ac ...... filin activity at invadopodia.

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type

label

A novel spatiotemporal RhoC ac ...... filin activity at invadopodia.

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A novel spatiotemporal RhoC ac ...... filin activity at invadopodia.

@nl

prefLabel

A novel spatiotemporal RhoC ac ...... filin activity at invadopodia.

@en

A novel spatiotemporal RhoC ac ...... filin activity at invadopodia.

@nl

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P356

J.CUB.2011.03.039

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Current Biology

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A novel spatiotemporal RhoC ac ...... filin activity at invadopodia.

@en

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John Condeelis

http://www.w3.org/2001/XMLSchema#string

Jose Javier Bravo-Cordero

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Matthew Oser

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Robert Eddy

http://www.w3.org/2001/XMLSchema#string

Xiaoming Chen

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P2860

Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase

14-3-3 regulates actin dynamics by stabilizing phosphorylated cofilin

RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis.

Molecular mechanisms of invadopodium formation: the role of the N-WASP-Arp2/3 complex pathway and cofilin

Characterization of p190RhoGEF, a RhoA-specific guanine nucleotide exchange factor that interacts with microtubules

Genomic analysis of metastasis reveals an essential role for RhoC

ROCK and Dia have opposing effects on adherens junctions downstream of Rho

Why three Rho proteins? RhoA, RhoB, RhoC, and cell motility

Faciogenital dysplasia protein Fgd1 regulates invadopodia biogenesis and extracellular matrix degradation and is up-regulated in prostate and breast cancer

Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation

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