A novel spatiotemporal RhoC activation pathway locally regulates cofilin activity at invadopodia.
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The dynamics of spatio-temporal Rho GTPase signaling: formation of signaling patternsPost-translational modification-regulated leukocyte adhesion and migrationCell polarity signaling in the plasticity of cancer cell invasivenessRho GTPase signalling in cell migrationPhosphorylation-mediated regulation of GEFs for RhoAThe interplay between the proteolytic, invasive, and adhesive domains of invadopodia and their roles in cancer invasionRhoC interacts with integrin α5β1 and enhances its trafficking in migrating pancreatic carcinoma cellsRgnef (p190RhoGEF) knockout inhibits RhoA activity, focal adhesion establishment, and cell motility downstream of integrinsA RhoC biosensor reveals differences in the activation kinetics of RhoA and RhoC in migrating cellsPodoplanin mediates ECM degradation by squamous carcinoma cells through control of invadopodia stabilityThe RhoGEF TEM4 Regulates Endothelial Cell Migration by Suppressing Actomyosin ContractilitySpatiotemporal analysis of RhoA/B/C activation in primary human endothelial cellsTks5 and SHIP2 regulate invadopodium maturation, but not initiation, in breast carcinoma cellsSpatiotemporal regulation of Src and its substrates at invadosomesSpatial regulation of RhoC activity defines protrusion formation in migrating cellsTransducer of Cdc42-dependent actin assembly promotes breast cancer invasion and metastasis.Cadherin-6B stimulates an epithelial mesenchymal transition and the delamination of cells from the neural ectoderm via LIMK/cofilin mediated non-canonical BMP receptor signaling.Adhesion rings surround invadopodia and promote maturation.Pattern formation of Rho GTPases in single cell wound healing.ARF1 regulates the Rho/MLC pathway to control EGF-dependent breast cancer cell invasionIntravital multiphoton imaging reveals multicellular streaming as a crucial component of in vivo cell migration in human breast tumorsFascin 1 is transiently expressed in mouse melanoblasts during development and promotes migration and proliferation.Macrophage contact induces RhoA GTPase signaling to trigger tumor cell intravasation.Chemotaxis in cancerA Trio-Rac1-Pak1 signalling axis drives invadopodia disassembly.DENND2B activates Rab13 at the leading edge of migrating cells and promotes metastatic behavior.Toward understanding RhoGTPase specificity: structure, function and local activation.Optical Tools To Study the Isoform-Specific Roles of Small GTPases in Immune Cells.High-resolution live-cell imaging and time-lapse microscopy of invadopodium dynamics and tracking analysis.p53 in cell invasion, podosomes, and invadopodiaRhoD Inhibits RhoC-ROCK-Dependent Cell Contraction via PAK6.Importance of RhoGTPases in formation, characteristics, and functions of invadosomes.Regulation of invadopodia by the tumor microenvironment.Identification of a novel actin-binding domain within the Rho guanine nucleotide exchange factor TEM4.Rho GTPase expression in human myeloid cellsCofilin activation during podosome belt formation in osteoclastsPodosomes in adhesion, migration, mechanosensing and matrix remodeling.TGF-β2-induced invadosomes in human trabecular meshwork cellsDense fibrillar collagen is a potent inducer of invadopodia via a specific signaling network.Profilin1 regulates invadopodium maturation in human breast cancer cells
P2860
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P2860
A novel spatiotemporal RhoC activation pathway locally regulates cofilin activity at invadopodia.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh
2011年學術文章
@zh-hant
name
A novel spatiotemporal RhoC ac ...... filin activity at invadopodia.
@en
A novel spatiotemporal RhoC ac ...... filin activity at invadopodia.
@nl
type
label
A novel spatiotemporal RhoC ac ...... filin activity at invadopodia.
@en
A novel spatiotemporal RhoC ac ...... filin activity at invadopodia.
@nl
prefLabel
A novel spatiotemporal RhoC ac ...... filin activity at invadopodia.
@en
A novel spatiotemporal RhoC ac ...... filin activity at invadopodia.
@nl
P2093
P2860
P1433
P1476
A novel spatiotemporal RhoC ac ...... filin activity at invadopodia.
@en
P2093
John Condeelis
Jose Javier Bravo-Cordero
Matthew Oser
Robert Eddy
Xiaoming Chen
P2860
P304
P356
10.1016/J.CUB.2011.03.039
P407
P577
2011-04-07T00:00:00Z