Geminin escapes degradation in G1 of mouse pluripotent cells and mediates the expression of Oct4, Sox2, and Nanog - Wikidata - wikimedia - TriplyDB

Geminin escapes degradation in G1 of mouse pluripotent cells and mediates the expression of Oct4, Sox2, and Nanog

Geminin escapes degradation in G1 of mouse pluripotent cells and mediates the expression of Oct4, Sox2, and Nanog

http://www.wikidata.org/entity/Q42722909

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Insights into APC/C: from cellular function to diseases and therapeutics Endoreplication The cell cycle and pluripotency Modulation of cell cycle control during oocyte-to-embryo transitions Regulation and Function of Cdt1; A Key Factor in Cell Proliferation and Genome Stability The dual roles of geminin during trophoblast proliferation and differentiation Hoxa9 transduction induces hematopoietic stem and progenitor cell activity through direct down-regulation of geminin protein Specificity and heterogeneity of terahertz radiation effect on gene expression in mouse mesenchymal stem cells.Geminin is required for the maintenance of pluripotency.Induced pluripotency leapfrogs ahead.Human cytomegalovirus infection interferes with the maintenance and differentiation of trophoblast progenitor cells of the human placenta Cell cycle adaptations of embryonic stem cells.Regulation of DNA replication during development.The dynamics of replication licensing in live Caenorhabditis elegans embryos.Geminin overexpression induces mammary tumors via suppressing cytokinesis.Distinct activities of the anaphase-promoting complex/cyclosome (APC/C) in mouse embryonic cells.Manipulation of Cell Cycle and Chromatin Configuration by Means of Cell-Penetrating Geminin Growing an Embryo from a Single Cell: A Hurdle in Animal Life."The Octet": Eight Protein Kinases that Control Mammalian DNA Replication.Re-replication induced by geminin depletion occurs from G2 and is enhanced by checkpoint activation.Scmh1 has E3 ubiquitin ligase activity for geminin and histone H2A and regulates geminin stability directly or indirectly via transcriptional repression of Hoxa9 and Hoxb4 DNA synthesis is required for reprogramming mediated by stem cell fusion Overexpression of cyclin D1 induces the reprogramming of differentiated epidermal cells into stem cell-like cells.Mice produced by mitotic reprogramming of sperm injected into haploid parthenogenotes.Concise Review: Control of Cell Fate Through Cell Cycle and Pluripotency Networks.Links between DNA Replication, Stem Cells and Cancer.Do all roads lead to Oct4? the emerging concepts of induced pluripotency.Transcription of the Geminin gene is regulated by a negative-feedback loop.Role of Geminin in cell fate determination of hematopoietic stem cells (HSCs).Concise Review: Geminin-A Tale of Two Tails: DNA Replication and Transcriptional/Epigenetic Regulation in Stem Cells.Regulation of Cell Division.Mechanisms of pluripotency maintenance in mouse embryonic stem cells.Oct4 promoter activity in stem cells obtained through somatic reprogramming.Geminin promotes an epithelial-to-mesenchymal transition in an embryonic stem cell model of gastrulation.Choosing Cell Fate Through a Dynamic Cell Cycle.Geminin regulates the transcriptional and epigenetic status of neuronal fate-promoting genes during mammalian neurogenesis Atypical heterochromatin organization and replication are rapidly acquired by somatic cells following fusion-mediated reprogramming by mouse ESCs.ZD7288, a blocker of the HCN channel family, increases doubling time of mouse embryonic stem cells and modulates differentiation outcomes in a context-dependent manner.Geminin restrains mesendodermal fate acquisition of embryonic stem cells and is associated with antagonism of Wnt signaling and enhanced polycomb-mediated repression.Geminin deletion in pre-meiotic DNA replication stage causes spermatogenesis defect and infertility.

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Geminin escapes degradation in G1 of mouse pluripotent cells and mediates the expression of Oct4, Sox2, and Nanog

http://www.wikidata.org/entity/Q42722909

description

2011 nî lūn-bûn

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2011年の論文

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2011年論文

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2011年論文

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2011年论文

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2011年论文

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name

Geminin escapes degradation in ...... ssion of Oct4, Sox2, and Nanog

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Geminin escapes degradation in ...... ssion of Oct4, Sox2, and Nanog

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Geminin escapes degradation in ...... ssion of Oct4, Sox2, and Nanog

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Geminin escapes degradation in ...... ssion of Oct4, Sox2, and Nanog

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Geminin escapes degradation in ...... ssion of Oct4, Sox2, and Nanog

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Geminin escapes degradation in ...... ssion of Oct4, Sox2, and Nanog

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J.CUB.2011.03.026

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Current Biology

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Geminin escapes degradation in ...... ssion of Oct4, Sox2, and Nanog

@en

P2093

Kikuë Tachibana-Konwalski

http://www.w3.org/2001/XMLSchema#string

Michael A Gonzalez

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Ronald A Laskey

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Sarah J Hyland

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Stephanie A Carter

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Valerie S Yang

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P2860

Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4

Inhibition of eukaryotic DNA replication by geminin binding to Cdt1

E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1)

Geminin, an inhibitor of DNA replication, is degraded during mitosis

Direct interaction of geminin and Six3 in eye development

Geminin regulates neuronal differentiation by antagonizing Brg1 activity

Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpoint

Geminin promotes neural fate acquisition of embryonic stem cells by maintaining chromatin in an accessible and hyperacetylated state

Differentiation of trophoblast stem cells into giant cells is triggered by p57/Kip2 inhibition of CDK1 activity

Selective killing of cancer cells by suppression of geminin activity

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3083515

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