about
Development of multiple strain competitive index assays for Listeria monocytogenes using pIMC; a new site-specific integrative vectorDirected evolution and targeted mutagenesis to murinize Listeria monocytogenes internalin A for enhanced infectivity in the murine oral infection model.Novel luciferase reporter system for in vitro and organ-specific monitoring of differential gene expression in Listeria monocytogenes.Two TIR-like domain containing proteins in a newly emerging zoonotic Staphylococcus aureus strain sequence type 398 are potential virulence factors by impacting on the host innate immune responseHyperexpression of α-hemolysin explains enhanced virulence of sequence type 93 community-associated methicillin-resistant Staphylococcus aureus.Complete Bypass of Restriction Systems for Major Staphylococcus aureus Lineages.Improved luciferase tagging system for Listeria monocytogenes allows real-time monitoring in vivo and in vitro.Transforming the untransformable: application of direct transformation to manipulate genetically Staphylococcus aureus and Staphylococcus epidermidis.Competing for Iron: Duplication and Amplification of the isd Locus in Staphylococcus lugdunensis HKU09-01 Provides a Competitive Advantage to Overcome Nutritional Limitation.Modelling staphylococcal pneumonia in a human 3D lung tissue model system delineates toxin-mediated pathology.Tools for functional postgenomic analysis of listeria monocytogenes.Subdomains N2N3 of fibronectin binding protein A mediate Staphylococcus aureus biofilm formation and adherence to fibrinogen using distinct mechanisms.De Novo Guanine Biosynthesis but Not the Riboswitch-Regulated Purine Salvage Pathway Is Required for Staphylococcus aureus Infection In VivoA point mutation in AgrC determines cytotoxic or colonizing properties associated with phenotypic variants of ST22 MRSA strainsEvolutionary origins of the emergent ST796 clone of vancomycin resistant Enterococcus faecium.Correspondence: Spontaneous secondary mutations confound analysis of the essential two-component system WalKR in Staphylococcus aureus.Large tandem chromosome expansions facilitate niche adaptation during persistent infection with drug-resistant Staphylococcus aureusGenomic analysis of ST88 community-acquired methicillin resistant Staphylococcus aureus in GhanaGenetic manipulation of Staphylococci-breaking through the barrier.Functional analysis of the first complete genome sequence of a multidrug resistant sequence type 2 Staphylococcus epidermidis.Fibronectin Binding Proteins SpsD and SpsL Both Support Invasion of Canine Epithelial Cells by Staphylococcus pseudintermedius.A novel Listeria monocytogenes-based DNA delivery system for cancer gene therapy.Vancomycin-intermediate Staphylococcus aureus isolates are attenuated for virulence when compared with susceptible progenitors.Manipulation of Autophagy in Phagocytes Facilitates Staphylococcus aureus Bloodstream Infection.The phage integrase vector pIPI03 allows RecA-independent, site-specific labelling of Staphylococcus lugdunensis strains.Sortase A promotes virulence in experimental Staphylococcus lugdunensis endocarditis.Topical Antibiotic Use Coselects for the Carriage of Mobile Genetic Elements Conferring Resistance to Unrelated Antimicrobials in Staphylococcus aureus.Convergent Evolution Driven by Rifampin Exacerbates the Global Burden of Drug-Resistant Staphylococcus aureus.Daptomycin selects for genetic and phenotypic adaptations leading to antibiotic tolerance in MRSA.Increasing tolerance of hospital Enterococcus faecium to handwash alcoholsGenomic analysis of multi-resistant associated with neonatal sepsisGlobal spread of three multidrug-resistant lineages of Staphylococcus epidermidisAgrD-dependent quorum sensing affects biofilm formation, invasion, virulence and global gene expression profiles inListeria monocytogenesInactivation of Listeria monocytogenes/Flavobacterium spp. biofilms using chlorine: impact of substrate, pH, time and concentrationSurvival of Listeria monocytogenes attached to stainless steel surfaces in the presence or absence of Flavobacterium sppComprehensive antibiotic-linked mutation assessment by resistance mutation sequencing (RM-seq)Evolution of Daptomycin Resistance in Coagulase-Negative Staphylococci Involves Mutations of the Essential Two-Component Regulator WalKRSuperantigen-Like Protein SSL1: A Toxic ProteaseWithin-host evolution of bovine Staphylococcus aureus selects for a SigB-deficient pathotype characterized by reduced virulence but enhanced proteolytic activity and biofilm formationStaphylococcus aureus small colony variants impair host immunity by activating host cell glycolysis and inducing necroptosis
P50
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P50
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հետազոտող
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Ian Monk
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Ian Monk
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Ian Monk
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Ian Monk
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Ian Monk
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Ian Monk
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Ian Monk
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Ian Monk
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Ian Monk
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Ian Monk
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Ian Monk
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Ian Monk
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Ian Monk
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Ian Monk
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Ian Monk
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P1153
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P21
P2798
P31
P496
0000-0001-6982-8074