Interaction with RXR is necessary for NPM-RAR-induced myeloid differentiation blockade.
about
LG-362B targets PML-RARα and blocks ATRA resistance of acute promyelocytic leukemia.NPM-RAR binding to TRADD selectively inhibits caspase activation, while allowing activation of NFκB and JNK.The leukemic oncoprotein NPM1-RARA inhibits TP53 activity.Extrinsic apoptosis is impeded by direct binding of the APL fusion protein NPM-RAR to TRADD.
P2860
Interaction with RXR is necessary for NPM-RAR-induced myeloid differentiation blockade.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Interaction with RXR is necessary for NPM-RAR-induced myeloid differentiation blockade.
@en
Interaction with RXR is necessary for NPM-RAR-induced myeloid differentiation blockade.
@nl
type
label
Interaction with RXR is necessary for NPM-RAR-induced myeloid differentiation blockade.
@en
Interaction with RXR is necessary for NPM-RAR-induced myeloid differentiation blockade.
@nl
prefLabel
Interaction with RXR is necessary for NPM-RAR-induced myeloid differentiation blockade.
@en
Interaction with RXR is necessary for NPM-RAR-induced myeloid differentiation blockade.
@nl
P2093
P2860
P1433
P1476
Interaction with RXR is necessary for NPM-RAR-induced myeloid differentiation blockade.
@en
P2093
Elizabeth A Rush
Irina Abecassis
Robert L Redner
Sheri L Pollock
P2860
P304
P356
10.1016/J.LEUKRES.2013.09.024
P577
2013-09-29T00:00:00Z