Molecular modelling and competition binding study of Br-noscapine and colchicine provide insight into noscapinoid-tubulin binding site

Molecular modelling and competition binding study of Br-noscapine and colchicine provide insight into noscapinoid-tubulin binding site

Item
http://www.wikidata.org/entity/Q42731418
The Noscapine Chronicle: A Pharmaco-Historic Biography of the Opiate Alkaloid Family and its Clinical ApplicationsRational design, synthesis, and biological evaluation of third generation α-noscapine analogues as potent tubulin binding anti-cancer agentsA new antiproliferative noscapine analogue: chemical synthesis and biological evaluationNovel 9'-substituted-noscapines: synthesis with Suzuki cross-coupling, structure elucidation and biological evaluationTheoretical and experimental study of polycyclic aromatic compounds as β-tubulin inhibitors.Peloruside, laulimalide, and noscapine interactions with beta-tubulin.Rational design of biaryl pharmacophore inserted noscapine derivatives as potent tubulin binding anticancer agents.Biology-oriented synthesis of a tetrahydroisoquinoline-based compound collection targeting microtubule polymerization.Synthesis and biological evaluation of N-substituted noscapine analogues.In silico inspired design and synthesis of a novel tubulin-binding anti-cancer drug: folate conjugated noscapine (Targetin).Isolation and characterization of bioactive compounds of Clematis gouriana Roxb. ex DC against snake venom phospholipase A2 (PLA2) computational and in vitro insights.Molecular modeling and prediction of binding mode and relative binding affinity of Art-Qui-OH with P. falciparum Histo-Aspartic Protease (HAP).Structural investigations into the binding mode of a novel noscapine analogue, 9-(4-vinylphenyl) noscapine, with tubulin by biochemical analyses and molecular dynamic simulations.
P2860

Molecular modelling and competition binding study of Br-noscapine and colchicine provide insight into noscapinoid-tubulin binding site

Item
http://www.wikidata.org/entity/Q42731418
description
2011 nî lūn-bûn
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年論文
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2011年论文
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2011年论文
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2011年论文
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name
Molecular modelling and compet ...... scapinoid-tubulin binding site
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Molecular modelling and compet ...... scapinoid-tubulin binding site
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Molecular modelling and compet ...... scapinoid-tubulin binding site
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Molecular modelling and compet ...... scapinoid-tubulin binding site
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Molecular modelling and compet ...... scapinoid-tubulin binding site
@en
Molecular modelling and compet ...... scapinoid-tubulin binding site
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Molecular modelling and compet ...... scapinoid-tubulin binding site
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P2093
P2860
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P356
10.1016/J.JMGM.2011.03.004
P433
P478
P577
P5875
P698
P932