about
Ribonucleotides misincorporated into DNA act as strand-discrimination signals in eukaryotic mismatch repairThe DNA damage checkpoint response requires histone H2B ubiquitination by Rad6-Bre1 and H3 methylation by Dot1.Phosphorylation of the budding yeast 9-1-1 complex is required for Dpb11 function in the full activation of the UV-induced DNA damage checkpoint.NER and DDR: classical music with new instruments.Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint.Elevated levels of the polo kinase Cdc5 override the Mec1/ATR checkpoint in budding yeast by acting at different steps of the signaling pathway.Dynamics of Rad9 chromatin binding and checkpoint function are mediated by its dimerization and are cell cycle-regulated by CDK1 activityMutations in the mitochondrial protease gene AFG3L2 cause dominant hereditary ataxia SCA28.Reduction of hRNase H2 activity in Aicardi-Goutières syndrome cells leads to replication stress and genome instabilityFunctional interplay between the 53BP1-ortholog Rad9 and the Mre11 complex regulates resection, end-tethering and repair of a double-strand break.The ribonuclease DIS3 promotes let-7 miRNA maturation by degrading the pluripotency factor LIN28B mRNA.RNase H and postreplication repair protect cells from ribonucleotides incorporated in DNACheckpoint mechanisms at the intersection between DNA damage and repair.Mind the gap: keeping UV lesions in check.To trim or not to trim: progression and control of DSB end resectionThe Incorporation of Ribonucleotides Induces Structural and Conformational Changes in DNA.Histone methyltransferase Dot1 and Rad9 inhibit single-stranded DNA accumulation at DSBs and uncapped telomeres.Study of UV-induced DNA Repair Factor Recruitment: Kinetics and Dynamics.Antagonistic Transcription Factor Complexes Modulate the Floral Transition in Rice.Measuring the Levels of Ribonucleotides Embedded in Genomic DNA.Characterization of Structural and Configurational Properties of DNA by Atomic Force Microscopy.Exo1 competes with repair synthesis, converts NER intermediates to long ssDNA gaps, and promotes checkpoint activation.DNA decay and limited Rad53 activation after liquid holding of UV-treated nucleotide excision repair deficient S. cerevisiae cellsRNase H activities counteract a toxic effect of Polymerase η in cells replicating with depleted dNTP poolsOne, No One, and One Hundred Thousand: The Many Forms of Ribonucleotides in DNA
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Federico Lazzaro
@ast
Federico Lazzaro
@en
Federico Lazzaro
@es
Federico Lazzaro
@nl
Federico Lazzaro
@sl
type
label
Federico Lazzaro
@ast
Federico Lazzaro
@en
Federico Lazzaro
@es
Federico Lazzaro
@nl
Federico Lazzaro
@sl
prefLabel
Federico Lazzaro
@ast
Federico Lazzaro
@en
Federico Lazzaro
@es
Federico Lazzaro
@nl
Federico Lazzaro
@sl
P1053
J-3585-2013
P106
P1153
6602899881
P21
P2381
P31
P3829
P496
0000-0001-6415-2925