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A novel 4EHP-GIGYF2 translational repressor complex is essential for mammalian developmentConserved GU-rich elements mediate mRNA decay by binding to CUG-binding protein 1Considerations when using the significance analysis of microarrays (SAM) algorithm31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part oneApoptosis resistance downstream of eIF4E: posttranscriptional activation of an anti-apoptotic transcript carrying a consensus hairpin structure.Identification of differential translation in genome wide studiesImproved precision and accuracy for microarrays using updated probe set definitions.Quantitative codon optimisation of DNA libraries encoding sub-random peptides: design and characterisation of a novel library encoding transmembrane domain peptidesSuppression of the DHX9 helicase induces premature senescence in human diploid fibroblasts in a p53-dependent manner.Epigenetic activation of a subset of mRNAs by eIF4E explains its effects on cell proliferationFibrotic myofibroblasts manifest genome-wide derangements of translational controlRole of 3'UTRs in the translation of mRNAs regulated by oncogenic eIF4E--a computational inferenceThe helicase protein DHX29 promotes translation initiation, cell proliferation, and tumorigenesisOxygen sufficiency controls TOP mRNA translation via the TSC-Rheb-mTOR pathway in a 4E-BP-independent manner.eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression.Data-driven unbiased curation of the TP53 tumor suppressor gene mutation database and validation by ultradeep sequencing of human tumors.The expression signature of in vitro senescence resembles mouse but not human aging.Distinct translational control in CD4+ T cell subsets.Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages.Assessment of mTOR-Dependent Translational Regulation of Interferon Stimulated GenesnanoCAGE reveals 5' UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAsDistinct perturbation of the translatome by the antidiabetic drug metforminmTOR coordinates protein synthesis, mitochondrial activity and proliferation.Toward a genome-wide landscape of translational controlComparative microarray analysis.mTORC1 and CK2 coordinate ternary and eIF4F complex assembly.RNAi screening uncovers Dhx9 as a modifier of ABT-737 resistance in an Eμ-myc/Bcl-2 mouse model.iGEMS: an integrated model for identification of alternative exon usage events.Phosphorylation of eIF4E promotes EMT and metastasis via translational control of SNAIL and MMP-3.Tumor cell survival dependence on the DHX9 DExH-box helicaseIL-15 activates mTOR and primes stress-activated gene expression leading to prolonged antitumor capacity of NK cells.Pericyte-fibroblast transition promotes tumor growth and metastasis.Fibrotic extracellular matrix activates a profibrotic positive feedback loop.Correlation of regional emphysema and lung cancer: a lung tissue research consortium-based study.Identification of a cell-of-origin for fibroblasts comprising the fibrotic reticulum in idiopathic pulmonary fibrosis.Translational control of immune responses: from transcripts to translatomes.Tissue distribution and differential expression of melanocortin 1 receptor, a malignant melanoma marker.Antisense PNA effects in Escherichia coli are limited by the outer-membrane LPS layer.Human muscle gene expression responses to endurance training provide a novel perspective on Duchenne muscular dystrophy.Functional comparison of single- and double-stranded siRNAs in mammalian cells.
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description
Zweeds onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Ola Larsson
@ast
Ola Larsson
@en
Ola Larsson
@es
Ola Larsson
@nl
Ola Larsson
@sl
type
label
Ola Larsson
@ast
Ola Larsson
@en
Ola Larsson
@es
Ola Larsson
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Ola Larsson
@sl
prefLabel
Ola Larsson
@ast
Ola Larsson
@en
Ola Larsson
@es
Ola Larsson
@nl
Ola Larsson
@sl
P106
P27
P31
P496
0000-0003-1412-1308