Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene
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miR-210 is overexpressed in late stages of lung cancer and mediates mitochondrial alterations associated with modulation of HIF-1 activityBig Data Analytics for Prostate RadiotherapyCurrent relevance of hypoxia in head and neck cancerIn vitro downregulated hypoxia transcriptome is associated with poor prognosis in breast cancer.Overexpression of POLQ confers a poor prognosis in early breast cancer patients.Most random gene expression signatures are significantly associated with breast cancer outcome.Gene Expression Analysis Reveals Distinct Pathways of Resistance to Bevacizumab in Xenograft Models of Human ER-Positive Breast CancerA generic cycling hypoxia-derived prognostic gene signature: application to breast cancer profiling.Significance analysis of prognostic signatures.Improving breast cancer survival analysis through competition-based multidimensional modeling.Exon-array profiling unlocks clinically and biologically relevant gene signatures from formalin-fixed paraffin-embedded tumour samples.The small-nucleolar RNAs commonly used for microRNA normalisation correlate with tumour pathology and prognosisHypoxia-inducible factors are required for chemotherapy resistance of breast cancer stem cellsMitochondrial DNA mutations in head and neck cancer are infrequent and lack prognostic utility.A multi-gene signature predicts outcome in patients with pancreatic ductal adenocarcinomaUnraveling the molecular genetics of head and neck cancer through genome-wide approachesPrestroke proteomic changes in cerebral microvessels in stroke-prone, transgenic[hCETP]-Hyperlipidemic, Dahl salt-sensitive hypertensive ratsEnsemble analyses improve signatures of tumour hypoxia and reveal inter-platform differences.Hypoxia induces a lipogenic cancer cell phenotype via HIF1α-dependent and -independent pathways.Evaluation of public cancer datasets and signatures identifies TP53 mutant signatures with robust prognostic and predictive valueSignaling pathways in breast cancer metastasis - novel insights from functional genomicsHIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungsHypoxic regulation of RIOK3 is a major mechanism for cancer cell invasion and metastasisGene expression and hypoxia in breast cancer.Evaluation of a hypoxia regulated gene panel in ovarian cancer.Hypoxia-induced p53 modulates both apoptosis and radiosensitivity via AKTPersonalized radiotherapy: concepts, biomarkers and trial designMolecular mechanisms mediating metastasis of hypoxic breast cancer cells.Carbonic anhydrase IX induction defines a heterogeneous cancer cell response to hypoxia and mediates stem cell-like properties and sensitivity to HDAC inhibition.Artificial neural network classifier predicts neuroblastoma patients' outcomeEstrogen receptor-α directly regulates the hypoxia-inducible factor 1 pathway associated with antiestrogen response in breast cancer.Distinct breast cancer stem/progenitor cell populations require either HIF1α or loss of PHD3 to expand under hypoxic conditionsMechanisms and consequences of ATMIN repression in hypoxic conditions: roles for p53 and HIF-1.Genomic alterations underlie a pan-cancer metabolic shift associated with tumour hypoxia.A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesis.Expression of miR-210 in relation to other measures of hypoxia and prediction of benefit from hypoxia modification in patients with bladder cancer.Radiogenomics Monitoring in Breast Cancer Identifies Metabolism and Immune Checkpoints as Early Actionable Mechanisms of Resistance to Anti-angiogenic Treatment.A 26-gene hypoxia signature predicts benefit from hypoxia-modifying therapy in laryngeal cancer but not bladder cancer.The BET inhibitor JQ1 selectively impairs tumour response to hypoxia and downregulates CA9 and angiogenesis in triple negative breast cancer.Genome-block expression-assisted association studies discover malaria resistance genes in Anopheles gambiae
P2860
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P2860
Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Large meta-analysis of multipl ...... ly prognostic hypoxia metagene
@en
Large meta-analysis of multipl ...... ly prognostic hypoxia metagene
@nl
type
label
Large meta-analysis of multipl ...... ly prognostic hypoxia metagene
@en
Large meta-analysis of multipl ...... ly prognostic hypoxia metagene
@nl
prefLabel
Large meta-analysis of multipl ...... ly prognostic hypoxia metagene
@en
Large meta-analysis of multipl ...... ly prognostic hypoxia metagene
@nl
P2860
P50
P356
P1476
Large meta-analysis of multipl ...... ly prognostic hypoxia metagene
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.BJC.6605450
P407
P577
2010-01-01T00:00:00Z