mTOR signaling: new networks for ALL. - Wikidata - wikimedia - TriplyDB

mTOR signaling: new networks for ALL.

mTOR signaling: new networks for ALL.

http://www.wikidata.org/entity/Q42743076

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Inhibition of mTOR kinase as a therapeutic target for acute myeloid leukemia.

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P2860

mTOR signaling: new networks for ALL.

http://www.wikidata.org/entity/Q42743076

description

2016 nî lūn-bûn

@nan

2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

2016年论文

@zh

2016年论文

@zh-cn

name

mTOR signaling: new networks for ALL.

@en

mTOR signaling: new networks for ALL.

@nl

type

label

mTOR signaling: new networks for ALL.

@en

mTOR signaling: new networks for ALL.

@nl

prefLabel

mTOR signaling: new networks for ALL.

@en

mTOR signaling: new networks for ALL.

@nl

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BLOOD-2016-03-703199

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mTOR signaling: new networks for ALL.

@en

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David A Fruman

http://www.w3.org/2001/XMLSchema#string

P2860

Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor

Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E

Mammalian target of rapamycin (mTOR) activity dependent phospho-protein expression in childhood acute lymphoblastic leukemia (ALL)

mTOR kinase inhibitors synergize with histone deacetylase inhibitors to kill B-cell acute lymphoblastic leukemia cells.

A Phase I/II Study of the mTOR Inhibitor Everolimus in Combination with HyperCVAD Chemotherapy in Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia

4EBP1/c-MYC/PUMA and NF-κB/EGR1/BIM pathways underlie cytotoxicity of mTOR dual inhibitors in malignant lymphoid cells.

PUMA and BIM are required for oncogene inactivation-induced apoptosis.

Target of rapamycin signaling in leukemia and lymphoma.

Direct transcriptional regulation of Bim by FoxO3a mediates STI571-induced apoptosis in Bcr-Abl-expressing cells.

mTOR inhibitor efficacy is determined by the eIF4E/4E-BP ratio.

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2658-2659

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scholarly article

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10.1182/BLOOD-2016-03-703199

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22

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127

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2016-06-01T00:00:00Z

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27257176

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4891950

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