about
The tetrahydroisoquinoline derivative SB269,652 is an allosteric antagonist at dopamine D3 and D2 receptorsNovel dimensions of D3 receptor function: Focus on heterodimerisation, transactivation and allosteric modulationDopamine D2-D3 receptor heteromers: pharmacological properties and therapeutic significanceStimulatory role of dopamine on fibroblast growth factor-2 expression in rat striatum.Genetic deletion of trace amine 1 receptors reveals their role in auto-inhibiting the actions of ecstasy (MDMA).Bright light exposure reduces TH-positive dopamine neurons: implications of light pollution in Parkinson's disease epidemiology.Experimental strategies for studying G protein-coupled receptor homo- and heteromerization with radioligand binding and signal transduction methods.The atypical antipsychotic clozapine selectively inhibits interleukin 8 (IL-8)-induced neutrophil chemotaxis.Presence of a putative steroidal allosteric site on glycoprotein hormone receptors.Species differences in the role of excitatory amino acids in experimental parkinsonism.Reconstitution of functional muscarinic receptors by co-expression of amino- and carboxyl-terminal receptor fragments.A quantitative analysis of antidepressant and antipsychotic prescriptions following an earthquake in Italy.Binding profile of the selective muscarinic receptor antagonist tripitramine.The thyroid disruptor 1,1,1-trichloro-2,2-bis(p-chlorophenyl)-ethane appears to be an uncompetitive inverse agonist for the thyrotropin receptor.Temporal and spatial patterns of expression of c-fos, zif/268, c-jun and jun-B mRNAs in rat brain following seizures evoked focally from the deep prepiriform cortex.The insecticide 1,1,1-trichloro-2,2-bis(p-chlorophenyl) ethane (DDT) alters the membrane raft location of the TSH receptor stably expressed in Chinese hamster ovary cells.D2/D3 dopamine receptor heterodimers exhibit unique functional properties.Apomorphine, dopamine and phenylethylamine reduce the proportion of phosphorylated insulin receptor substrate 1.An unusual form of the association binding kinetics of N-[3H]methylscopolamine to the split muscarinic M2trunk/M2tail receptor.Dextromethorphan prevents the diethyldithiocarbamate enhancement of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in mice.Functional rescue of the inactive splice variant of the dopamine D3 receptor D3nf.Potent activation of dopamine D3/D2 heterodimers by the antiparkinsonian agents, S32504, pramipexole and ropinirole.The paired activation of the two components of the muscarinic M3 receptor dimer is required for induction of ERK1/2 phosphorylation.Thyroid disruptor 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) prevents internalization of TSH receptor.Paired activation of two components within muscarinic M3 receptor dimers is required for recruitment of beta-arrestin-1 to the plasma membrane.Partial agonist actions at dopamine D2L receptors are modified by co-transfection of D3 receptors: potential role of heterodimer formation.Deoxamuscaroneoxime derivatives as useful muscarinic agonists to explore the muscarinic subsite: demox, a modulator of orthosteric and allosteric sites at cardiac muscarinic M2 receptors.S33138 [N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b-tetrahydro[1]-benzopyrano[3,4-c]pyrrol-2(3H)-yl)-ethyl]phenylacetamide], a preferential dopamine D3 versus D2 receptor antagonist and potential antipsychotic agent: I. Receptor-binding profile and functioProperties of 3H-MPTP binding sites in human blood platelets.High affinity binding sites for 1-methyl-4-phenyl-pyridinium ion (MPP+) are present in mouse brain.Blockade of GABA receptors in superior colliculus protects against focally evoked limbic motor seizures.Expression of c-fos mRNA following seizures evoked from an epileptogenic site in the deep prepiriform cortex: regional distribution in brain as shown by in situ hybridization.Lack of proconvulsant action of GABA depletion in substantia nigra in several seizure models.L-deprenyl fails to protect mesencephalic dopamine neurons and PC12 cells from the neurotoxic effect of 1-methyl-4-phenylpyridinium ion.Nitric oxide synthase inhibition reverts muscarinic receptor down-regulation induced by pilocarpine- and kainic acid-evoked seizures in rat fronto-parietal cortex.Selective stimulation of kainate but not quisqualate or NMDA receptors in substantia nigra evokes limbic motor seizures.Differential induction of adenylyl cyclase supersensitivity by antiparkinson drugs acting as agonists at dopamine D1/D2/D3 receptors vs D2/D3 receptors only: parallel observations from co-transfected human and native cerebral receptors.Partial agonist actions of aripiprazole and the candidate antipsychotics S33592, bifeprunox, N-desmethylclozapine and preclamol at dopamine D(2L) receptors are modified by co-transfection of D(3) receptors: potential role of heterodimer formation.Functional role of the third cytoplasmic loop in muscarinic receptor dimerization.Eyes as gateways for environmental light to the substantia nigra: relevance in Parkinson's disease
P50
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P50
description
hulumtues
@sq
researcher
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wetenschapper
@nl
հետազոտող
@hy
name
Roberto Maggio
@ast
Roberto Maggio
@en
Roberto Maggio
@es
Roberto Maggio
@nl
Roberto Maggio
@sl
type
label
Roberto Maggio
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Roberto Maggio
@en
Roberto Maggio
@es
Roberto Maggio
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Roberto Maggio
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altLabel
R Maggio
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prefLabel
Roberto Maggio
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Roberto Maggio
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Roberto Maggio
@es
Roberto Maggio
@nl
Roberto Maggio
@sl
P106
P1153
7005576147
P21
P31
P496
0000-0003-4436-2356