about
Template. Phosphorothioate oligonucleotides duplexes as inhibitors of HIV-1 reverse transcriptaseUptake and quantification of intracellular concentration of lipophilic pro-oligonucleotides in HeLa cells.Synthesis of a library of fucosylated glycoclusters and determination of their binding toward Pseudomonas aeruginosa lectin B (PA-IIL) using a DNA-based carbohydrate microarray.Use of MALDI-TOF mass spectrometry to monitor solid-phase synthesis of oligonucleotides.Use of 2-(tert-butyldiphenylsilyloxymethyl) benzoyl as N-protecting group for the synthesis of prooligonucleotides.Universal solid supports for the synthesis of oligonucleotides via a transesterification of H-phosphonate diester linkage.Combinatorial and automated synthesis of phosphodiester galactosyl cluster on solid support by click chemistry assisted by microwaves.Phosphoramidate dinucleosides as hepatitis C virus polymerase inhibitors.Synthesis of mannose and galactose oligonucleotide conjugates by bi-click chemistry.Azide solid support for 3'-conjugation of oligonucleotides and their circularization by click chemistry.Measurement of enzymatic activity and specificity of human and avian influenza neuraminidases from whole virus by glycoarray and MALDI-TOF mass spectrometry.The influence of the aromatic aglycon of galactoclusters on the binding of LecA: a case study with O-phenyl, S-phenyl, O-benzyl, S-benzyl, O-biphenyl and O-naphthyl aglycons.Assessment of the Full Compatibility of Copper(I)-Catalyzed Alkyne-Azide Cycloaddition and Oxime Click Reactions for bis-Labelling of OligonucleotidesGlycoclusters on oligonucleotide and PNA scaffolds: synthesis and applications.DNA directed immobilization glycocluster array: applications and perspectives.Fluorescent thrombin binding aptamer-tagged nanoparticles for an efficient and reversible control of thrombin activity.Design and Synthesis of Galactosylated Bifurcated Ligands with Nanomolar Affinity for Lectin LecA from Pseudomonas aeruginosa.Toward the Rational Design of Galactosylated Glycoclusters That Target Pseudomonas aeruginosa Lectin A (LecA): Influence of Linker Arms That Lead to Low-Nanomolar Multivalent Ligands.Importance of topology for glycocluster binding to Pseudomonas aeruginosa and Burkholderia ambifaria bacterial lectins.Fluorescence enhancement upon G-quadruplex folding: synthesis, structure, and biophysical characterization of a dansyl/cyclodextrin-tagged thrombin binding aptamer.Comparative evaluation of seven oligonucleotide analogues as potential antisense agents.3'-Deoxy phosphoramidate dinucleosides as improved inhibitors of hepatitis C virus subgenomic replicon and NS5B polymerase activity.Alpha-DNA. IV: Alpha-anomeric and beta-anomeric tetrathymidylates covalently linked to intercalating oxazolopyridocarbazole. Synthesis, physicochemical properties and poly (rA) binding.Effects of the Surface Densities of Glycoclusters on the Determination of Their IC50 and Kd Value Determination by Using a Microarray.Synthesis of 5' cap-0 and cap-1 RNAs using solid-phase chemistry coupled with enzymatic methylation by human (guanine-N⁷)-methyl transferase.Development of innovative and versatile polythiol probes for use on ELOSA or electrochemical biosensors: application in hepatitis C virus genotyping.5'-Bis-conjugation of oligonucleotides by amidative oxidation and click chemistry.Oligonucleotide carbohydrate-centered galactosyl cluster conjugates synthesized by click and phosphoramidite chemistries.Delta-di-carboxybutyl phosphoramidate of 2'-deoxycytidine-5'-monophosphate as substrate for DNA polymerization by HIV-1 reverse transcriptase.Design of triazole-tethered glycoclusters exhibiting three different spatial arrangements and comparative study of their affinities towards PA-IL and RCA 120 by using a dna-based glycoarray.DNA-directed immobilisation of glycomimetics for glycoarrays application: comparison with covalent immobilisation, and development of an on-chip IC50 measurement assay.Polarity of annealing and structural analysis of the RNase H resistant alpha-5'-d[TACACA].beta-5'-r[AUGUGU] hybrid determined by high-field 1H, 13C, and 31P NMR analysis.Quantitative analysis (K(d) and IC(50)) of glycoconjugates interactions with a bacterial lectin on a carbohydrate microarray with DNA Direct Immobilization (DDI).Improved Performance of DNA Microarray Multiplex Hybridization Using Probes Anchored at Several Points by Thiol-Ene or Thiol-Yne Coupling Chemistry.Mannose-centered aromatic galactoclusters inhibit the biofilm formation of Pseudomonas aeruginosa.DNA-based carbohydrate biochips: a platform for surface glyco-engineering.Structure binding relationship of galactosylated Glycoclusters toward Pseudomonas aeruginosa lectin LecA using a DNA-based carbohydrate microarray.Alpha-anomeric DNA: beta-RNA hybrids as new synthetic inhibitors of Escherichia coli RNase H, Drosophila embryo RNase H and M-MLV reverse transcriptase.Sugar modified oligonucleotides: synthesis, nuclease resistance and base pairing of oligodeoxynucleotides containing 1-(4'-thio-beta-D-ribofuranosyl)-thymine.Sugar modified oligonucleotides. III (1). Synthesis, nuclease resistance and base pairing properties of alpha- and beta-L-octathymidylates.
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
François Morvan
@ast
François Morvan
@en
François Morvan
@es
François Morvan
@nl
François Morvan
@sl
type
label
François Morvan
@ast
François Morvan
@en
François Morvan
@es
François Morvan
@nl
François Morvan
@sl
prefLabel
François Morvan
@ast
François Morvan
@en
François Morvan
@es
François Morvan
@nl
François Morvan
@sl
P1053
G-8507-2011
P106
P21
P31
P3829
P496
0000-0001-5077-0028