about
Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 EnvStructure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9Developmental pathway for potent V1V2-directed HIV-neutralizing antibodiesStructures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine designVaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2Somatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing AntibodiesDynamic basis for one-dimensional DNA scanning by the mismatch repair complex Msh2-Msh6.Single-molecule imaging reveals target-search mechanisms during DNA mismatch repair.Nanofabricated racks of aligned and anchored DNA substrates for single-molecule imaging.Transplanting supersites of HIV-1 vulnerability.Visualizing one-dimensional diffusion of eukaryotic DNA repair factors along a chromatin lattice.AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges.Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody.N332-Directed broadly neutralizing antibodies use diverse modes of HIV-1 recognition: inferences from heavy-light chain complementation of function.Conformational dynamics of single HIV-1 envelope trimers on the surface of native virionsStructure and immune recognition of trimeric pre-fusion HIV-1 Env.Single-Chain Soluble BG505.SOSIP gp140 Trimers as Structural and Antigenic Mimics of Mature Closed HIV-1 Env.Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability.A short segment of the HIV-1 gp120 V1/V2 region is a major determinant of resistance to V1/V2 neutralizing antibodiesStructure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape.Viral variants that initiate and drive maturation of V1V2-directed HIV-1 broadly neutralizing antibodiesNew Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional PotencyCrystal structures of the tryptophan repressor binding protein WrbA and complexes with flavin mononucleotide.Envelope residue 375 substitutions in simian-human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaquesVisualizing one-dimensional diffusion of proteins along DNA.Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity.The promoter-search mechanism of Escherichia coli RNA polymerase is dominated by three-dimensional diffusionCorrection: Targeted Isolation of Antibodies Directed against Major Sites of SIV Env Vulnerability.Target search dynamics during post-replicative mismatch repair.V1/V2-directed antibodies elicited in RV144 vaccinees bind to a structurally polymorphic site.A short segment in the HIV-1 gp120 V1/V2 region is a major determinant of neutralization resistance to PG9-like antibodies.Structure of Escherichia coli YfdW, a type III CoA transferase.HIV-1 Env trimer opens through an asymmetric intermediate in which individual protomers adopt distinct conformations.Uncleaved Soluble gp140 Constructs with Retained Native-like Trimer Conformation and Antigenicity.Recombinant Env proteins that bind the quaternary-specific, V1/V2-directed PGT antibodies.Sequencing HIV-neutralizing antibody exons and introns reveals detailed aspects of lineage maturationDNA Curtains for High-Throughput Single-Molecule Optical ImagingStructure of serine acetyltransferase fromHaemophilus influenzaeRdSingle-Molecule FRET Delineates Asymmetric Trimer Conformations during HIV-1 EntryRational design and in vivo selection of SHIVs encoding transmitted/founder subtype C HIV-1 envelopes
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description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Jason Gorman
@ast
Jason Gorman
@en
Jason Gorman
@es
Jason Gorman
@nl
Jason Gorman
@sl
type
label
Jason Gorman
@ast
Jason Gorman
@en
Jason Gorman
@es
Jason Gorman
@nl
Jason Gorman
@sl
altLabel
Jay Gorman
@en
prefLabel
Jason Gorman
@ast
Jason Gorman
@en
Jason Gorman
@es
Jason Gorman
@nl
Jason Gorman
@sl
P106
P21
P31
P496
0000-0002-3775-6560