HoxA9 regulated Bcl-2 expression mediates survival of myeloid progenitors and the severity of HoxA9-dependent leukemia.

HoxA9 regulated Bcl-2 expression mediates survival of myeloid progenitors and the severity of HoxA9-dependent leukemia.

Item
http://www.wikidata.org/entity/Q42770287
Role of HOXA9 in leukemia: dysregulation, cofactors and essential targetsBCL-2 is dispensable for thrombopoiesis and platelet survivalProsurvival Bcl-2 family members affect autophagy only indirectly, by inhibiting Bax and Bak.The caspase-8 inhibitor emricasan combines with the SMAC mimetic birinapant to induce necroptosis and treat acute myeloid leukemia.A transcriptomic signature mediated by HOXA9 promotes human glioblastoma initiation, aggressiveness and resistance to temozolomideCCI-007, a novel small molecule with cytotoxic activity against infant leukemia with MLL rearrangements.Higher expression levels of the HOXA9 gene, closely associated with MLL-PTD and EZH2 mutations, predict inferior outcome in acute myeloid leukemia.Molecular synergy underlies the co-occurrence patterns and phenotype of NPM1-mutant acute myeloid leukemia.HOX gene expression predicts response to BCL-2 inhibition in acute myeloid leukemia.HOXB7 promotes tumor progression via bFGF-induced activation of MAPK/ERK pathway and indicated poor prognosis in hepatocellular carcinoma.CDK4/6 Inhibitor PD 0332991 Sensitizes Acute Myeloid Leukemia to Cytarabine-Mediated Cytotoxicity.Dysregulation of BCL-2 family proteins by leukemia fusion genes.Overexpression of NAC1 confers drug resistance via HOXA9 in colorectal carcinoma cells.MicroRNA-182 downregulates Wnt/β-catenin signaling, inhibits proliferation, and promotes apoptosis in human osteosarcoma cells by targeting HOXA9.A dual role for the N-terminal domain of the IL-3 receptor in cell signalling.Insulin-like growth factor 1 is a direct HOXA9 target important for hematopoietic transformation.HOXA9 inhibits HIF-1α-mediated glycolysis through interacting with CRIP2 to repress cutaneous squamous cell carcinoma development.
P2860

HoxA9 regulated Bcl-2 expression mediates survival of myeloid progenitors and the severity of HoxA9-dependent leukemia.

Item
http://www.wikidata.org/entity/Q42770287
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
HoxA9 regulated Bcl-2 expressi ...... y of HoxA9-dependent leukemia.
@en
HoxA9 regulated Bcl-2 expressi ...... y of HoxA9-dependent leukemia.
@nl
type
label
HoxA9 regulated Bcl-2 expressi ...... y of HoxA9-dependent leukemia.
@en
HoxA9 regulated Bcl-2 expressi ...... y of HoxA9-dependent leukemia.
@nl
prefLabel
HoxA9 regulated Bcl-2 expressi ...... y of HoxA9-dependent leukemia.
@en
HoxA9 regulated Bcl-2 expressi ...... y of HoxA9-dependent leukemia.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
HoxA9 regulated Bcl-2 expressi ...... y of HoxA9-dependent leukemia.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932