Sphingosine kinase type 2 is a putative BH3-only protein that induces apoptosis.
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FHL2/SLIM3 decreases cardiomyocyte survival by inhibitory interaction with sphingosine kinase-1Phosphorylation-dependent translocation of sphingosine kinase to the plasma membrane drives its oncogenic signallingRoles of bioactive sphingolipids in cancer biology and therapeuticsA house divided: ceramide, sphingosine, and sphingosine-1-phosphate in programmed cell deathEmerging role of sphingosine-1-phosphate signaling in head and neck squamous cell carcinomaThe compartmentalization and translocation of the sphingosine kinases: mechanisms and functions in cell signaling and sphingolipid metabolismSphingolipids in spinal cord injuryIsc1 regulates sphingolipid metabolism in yeast mitochondria.The divergent roles of autophagy in ischemia and preconditioningBH3-only proteins: a 20-year stock-takeCharacterization of isoenzyme-selective inhibitors of human sphingosine kinasesBiological characterization of 3-(2-amino-ethyl)-5-[3-(4-butoxyl-phenyl)-propylidene]-thiazolidine-2,4-dione (K145) as a selective sphingosine kinase-2 inhibitor and anticancer agentEssential role for sphingosine kinases in neural and vascular developmentTranscription factor specificity protein 1 (Sp1) is the main regulator of nerve growth factor-induced sphingosine kinase 1 gene expression of the rat pheochromocytoma cell line, PC12Cloning and characterization of rat sphingosine kinase 1 with an N-terminal extensionNovel role of sphingosine kinase 1 as a mediator of neurotrophin-3 action in oligodendrocyte progenitorsSphingosine-1-Phosphate Metabolism and Its Role in the Development of Inflammatory Bowel DiseaseSphingosine Kinase 2 Deficiency Attenuates Kidney Fibrosis via IFN-γ.Structure-activity relationship studies and in vivo activity of guanidine-based sphingosine kinase inhibitors: discovery of SphK1- and SphK2-selective inhibitors.Effect of alkyl chain length on sphingosine kinase 2 selectivity.Sphingosine kinase type 2 inhibition elevates circulating sphingosine 1-phosphate.Design, synthesis and biological activity of sphingosine kinase 2 selective inhibitors.Development of amidine-based sphingosine kinase 1 nanomolar inhibitors and reduction of sphingosine 1-phosphate in human leukemia cells.Discovery, biological evaluation, and structure-activity relationship of amidine based sphingosine kinase inhibitorsDivergent roles of sphingosine kinases in kidney ischemia-reperfusion injury.Sphingosine-1-phosphate receptors: biology and therapeutic potential in kidney diseaseA novel mitochondrial sphingomyelinase in zebrafish cells.The expression of sphingosine kinase-1 in head and neck carcinomaRe-configuration of sphingolipid metabolism by oncogenic transformation.Sphingosine kinase and sphingosine 1-phosphate in cardioprotection.Expression and regulation of enzymes in the ceramide metabolic pathway in human retinal pigment epithelial cells and their relevance to retinal degeneration.Sphingosine 1-Phosphate Receptors: Do They Have a Therapeutic Potential in Cardiac Fibrosis?The S1P2 receptor negatively regulates platelet-derived growth factor-induced motility and proliferation.Mammalian sphingosine kinase (SphK) isoenzymes and isoform expression: challenges for SphK as an oncotarget.Sphingosine kinase: Role in regulation of bioactive sphingolipid mediators in inflammation.Multiple roles for sphingolipids in steroid hormone biosynthesisPreconditioning stimuli induce autophagy via sphingosine kinase 2 in mouse cortical neurons.BH3-only proteins in apoptosis and beyond: an overview.Extracellular and intracellular actions of sphingosine-1-phosphateAntiestrogenic effects of the novel sphingosine kinase-2 inhibitor ABC294640
P2860
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P2860
Sphingosine kinase type 2 is a putative BH3-only protein that induces apoptosis.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Sphingosine kinase type 2 is a putative BH3-only protein that induces apoptosis.
@en
Sphingosine kinase type 2 is a putative BH3-only protein that induces apoptosis.
@nl
type
label
Sphingosine kinase type 2 is a putative BH3-only protein that induces apoptosis.
@en
Sphingosine kinase type 2 is a putative BH3-only protein that induces apoptosis.
@nl
prefLabel
Sphingosine kinase type 2 is a putative BH3-only protein that induces apoptosis.
@en
Sphingosine kinase type 2 is a putative BH3-only protein that induces apoptosis.
@nl
P2093
P356
P1476
Sphingosine kinase type 2 is a putative BH3-only protein that induces apoptosis.
@en
P2093
Heidi Sankala
Jerold Chun
Meryem Bektas
Michael Maceyka
Rachelle E Toman
Shawn G Payne
Sheldon Milstien
Sravan K Goparaju
Victor E Nava
P304
40330-40336
P356
10.1074/JBC.M304455200
P407
P577
2003-06-30T00:00:00Z