about
DAX-1 acts as a novel corepressor of orphan nuclear receptor HNF4alpha and negatively regulates gluconeogenic enzyme gene expressionSuppressor of MEK null (SMEK)/protein phosphatase 4 catalytic subunit (PP4C) is a key regulator of hepatic gluconeogenesisTCF7L2 modulates glucose homeostasis by regulating CREB- and FoxO1-dependent transcriptional pathway in the liverThe CREB coactivator TORC2 is a key regulator of fasting glucose metabolismOrphan nuclear receptor DAX-1 acts as a novel corepressor of liver X receptor alpha and inhibits hepatic lipogenesis.Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues.CREB and FoxO1: two transcription factors for the regulation of hepatic gluconeogenesisAMPK-dependent repression of hepatic gluconeogenesis via disruption of CREB.CRTC2 complex by orphan nuclear receptor small heterodimer partner.PPAR-γ activation increases insulin secretion through the up-regulation of the free fatty acid receptor GPR40 in pancreatic β-cellsRing finger protein20 regulates hepatic lipid metabolism through protein kinase A-dependent sterol regulatory element binding protein1c degradationCannabinoid receptor type 1 (CB1R) signaling regulates hepatic gluconeogenesis via induction of endoplasmic reticulum-bound transcription factor cAMP-responsive element-binding protein H (CREBH) in primary hepatocytesCurcumin differentially regulates endoplasmic reticulum stress through transcriptional corepressor SMILE (small heterodimer partner-interacting leucine zipper protein)-mediated inhibition of CREBH (cAMP responsive element-binding protein H)Orphan nuclear receptor estrogen-related receptor γ (ERRγ) is key regulator of hepatic gluconeogenesis.Activation of cannabinoid receptor type 1 (Cb1r) disrupts hepatic insulin receptor signaling via cyclic AMP-response element-binding protein H (Crebh)-mediated induction of Lipin1 gene.Phosphoenolpyruvate carboxykinase and glucose-6-phosphatase are required for steroidogenesis in testicular Leydig cellsC1-Ten is a protein tyrosine phosphatase of insulin receptor substrate 1 (IRS-1), regulating IRS-1 stability and muscle atrophy.Transcriptional cross talk between orphan nuclear receptor ERRγ and transmembrane transcription factor ATF6α coordinates endoplasmic reticulum stress response.Inverse agonist of nuclear receptor ERRγ mediates antidiabetic effect through inhibition of hepatic gluconeogenesis.The orphan nuclear receptor estrogen receptor-related receptor gamma negatively regulates BMP2-induced osteoblast differentiation and bone formation.Estrogen-related receptor γ controls hepatic CB1 receptor-mediated CYP2E1 expression and oxidative liver injury by alcohol.Ursodeoxycholic acid inhibits liver X receptor α-mediated hepatic lipogenesis via induction of the nuclear corepressor SMILE.Orphan nuclear receptor Errγ induces C-reactive protein gene expression through induction of ER-bound Bzip transmembrane transcription factor CREBH.Transcriptional regulators of hepatic gluconeogenesis.Glucose and insulin function through two distinct transcription factors to stimulate expression of lipogenic enzyme genes in liver.Different sterol regulatory element-binding protein-1 isoforms utilize distinct co-regulatory factors to activate the promoter for fatty acid synthase.Retinoic acid-related orphan receptor alpha reprograms glucose metabolism in glutamine-deficient hepatoma cells.Arginine methylation of CRTC2 is critical in the transcriptional control of hepatic glucose metabolism.Dual role of the coactivator TORC2 in modulating hepatic glucose output and insulin signaling.CREB controls hepatic lipid metabolism through nuclear hormone receptor PPAR-gamma.HBx induces the proliferation of hepatocellular carcinoma cells via AP1 over-expressed as a result of ER stress.Endoplasmic reticulum stress promotes LIPIN2-dependent hepatic insulin resistance.Adiponectin and thiazolidinedione targets CRTC2 to regulate hepatic gluconeogenesis.SIK2 is critical in the regulation of lipid homeostasis and adipogenesis in vivo.Regulation of hepatic gluconeogenesis by an ER-bound transcription factor, CREBH.Smad6 inhibits non-canonical TGF-β1 signalling by recruiting the deubiquitinase A20 to TRAF6.Involvement of a unique carbohydrate-responsive factor in the glucose regulation of rat liver fatty-acid synthase gene transcription.PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3.TORC2 regulates hepatic insulin signaling via a mammalian phosphatidic acid phosphatase, LIPIN1.Diabetes: outfoxing insulin resistance?Fatty acids and insulin resistance: a perfect storm.
P50
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Seung-Hoi Koo
@ast
Seung-Hoi Koo
@en
Seung-Hoi Koo
@es
Seung-Hoi Koo
@nl
Seung-Hoi Koo
@sl
type
label
Seung-Hoi Koo
@ast
Seung-Hoi Koo
@en
Seung-Hoi Koo
@es
Seung-Hoi Koo
@nl
Seung-Hoi Koo
@sl
prefLabel
Seung-Hoi Koo
@ast
Seung-Hoi Koo
@en
Seung-Hoi Koo
@es
Seung-Hoi Koo
@nl
Seung-Hoi Koo
@sl
P1053
E-2763-2015
P106
P1153
55661692800
P31
P3829
P496
0000-0001-8769-2879