about
Selective plasma hydrolysis of glucocorticoid gamma-lactones and cyclic carbonates by the enzyme paraoxonase: an ideal plasma inactivation mechanismCation Charge Density and Precatalyst Selection in Group 2-Catalyzed Aminoalkene HydroaminationNovel glucocorticoid antedrugs possessing a 17beta-(gamma-lactone) ring.Synthetic Studies Towards the Core Structure of Nakadomarin A by a Thioamide-Based Strategy.Lead identification and structure-activity relationships of heteroarylpyrazole arylsulfonamides as allosteric CC-chemokine receptor 4 (CCR4) antagonists.Lead identification of benzimidazolone and azabenzimidazolone arylsulfonamides as CC-chemokine receptor 4 (CCR4) antagonists.Short and efficient syntheses of protoberberine alkaloids using palladium-catalyzed enolate arylationModular isoquinoline synthesis using catalytic enolate arylation and in situ functionalizationInhibitors of cholesterol biosynthesis. 2. 3,5-Dihydroxy-7-(N-pyrrolyl)-6-heptenoates, a novel series of HMG-CoA reductase inhibitors.Carbodiimide insertion reactions of homoleptic heavier alkaline earth amides and phosphides.Synthesis and characterization of coronanes: multicyclopropane-fused macrocyclic arrays.Potassium trimethylsilanolate induced cleavage of 1,3-oxazolidin-2- and 5-ones, and application to the synthesis of (R)-salmeterol.Synthesis of (R)-alpha-benzylmethionine: a novel rearrangement during alkylation of the Seebach (R)-methionine oxazolidinone.Synthesis of the beta 2 agonist (R)-salmeterol using a sequence of supported reagents and scavenging agents.Intramolecular hydroamination of aminoalkenes by calcium and magnesium complexes: a synthetic and mechanistic study.Insertion reactions of beta-diketiminate-stabilised calcium amides with 1,3-dialkylcarbodiimides.Catalytic 2,3,4-hexatriene formation by terminal alkyne coupling at calcium.Beta-diketiminato calcium and magnesium amides; model complexes for hydroamination catalysis.Synthesis and structure-activity relationships of long-acting beta2 adrenergic receptor agonists incorporating arylsulfonamide groups.Bis(trimethylsilyl)methyl derivatives of calcium, strontium and barium: potentially useful dialkyls of the heavy alkaline earth elements.Triazenide complexes of the heavier alkaline earths: synthesis, characterization, and suitability for hydroamination catalysis.The discovery of long-acting saligenin β₂ adrenergic receptor agonists incorporating hydantoin or uracil rings.The discovery of long-acting saligenin β₂ adrenergic receptor agonists incorporating a urea group.Reversibility in the protonolysis of a beta-diketiminate stabilised calcium bis(trimethylsilyl)amide with benzylamine.Synthesis and structure-activity relationships of indazole arylsulfonamides as allosteric CC-chemokine receptor 4 (CCR4) antagonists.4-acyl-1-(4-aminoalkoxyphenyl)-2-ketopiperazines as a novel class of non-brain-penetrant histamine H3 receptor antagonists.Bis(diphenylphosphido) derivatives of the heavier group 2 elements.Identification of pyrazolopyrimidine arylsulfonamides as CC-chemokine receptor 4 (CCR4) antagonists.Design of Phthalazinone Amide Histamine H1 Receptor Antagonists for Use in Rhinitis.Studies on the stereochemical assignment of 3-acylidene 2-oxindoles.The discovery of quinoline based single-ligand human H1 and H3 receptor antagonists.Synthesis and determination of absolute configuration of a non-peptidic αvβ6 integrin antagonist for the treatment of idiopathic pulmonary fibrosis.2,8-Diazaspiro[4.5]decan-8-yl)pyrimidin-4-amine potent CCR4 antagonists capable of inducing receptor endocytosis.Discovery of a rapidly metabolized, long-acting β(2) adrenergic receptor agonist with a short onset time incorporating a sulfone group suitable for once-daily dosing.Synthesis of Functionalized Pyridines via a Regioselective Oxazoline Promoted C-H Amidation Reaction.Oxazole synthesis with minimal purification: synthesis and application of a ROMPgel Tosmic reagent.A mild and regioselective route to functionalized quinazolines.Heavier Group 2 Metals and Intermolecular Hydroamination: A Computational and Synthetic Assessmentβ-Diketiminate C–H activation with heavier group 2 alkylsHeavier group 2 element-catalysed hydroamination of isocyanates
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P50
description
hulumtues
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researcher
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wetenschapper
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հետազոտող
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Panayiotis Procopiou
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Panayiotis Procopiou
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Panayiotis Procopiou
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Panayiotis Procopiou
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Panayiotis Procopiou
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type
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Panayiotis Procopiou
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Panayiotis Procopiou
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Panayiotis Procopiou
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Panayiotis Procopiou
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Panayiotis Procopiou
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Pan A. Procopiou
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Panayiotis Procopiou
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Panayiotis Procopiou
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Panayiotis Procopiou
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Panayiotis Procopiou
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Panayiotis Procopiou
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P106
P108
P1153
7003961052
P21
P31
P496
0000-0001-5907-116X