Effects of bombesin and insulin on inositol (1,4,5)trisphosphate and inositol (1,3,4)trisphosphate formation in Swiss 3T3 cells.
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[D-Arg1,D-Phe5,D-Trp7,9,Leu11]substance P, a potent bombesin antagonist in murine Swiss 3T3 cells, inhibits the growth of human small cell lung cancer cells in vitro.Malignant transformation by ras and other oncogenes produces common alterations in inositol phospholipid signaling pathwaysEffects of ras-encoded proteins and platelet-derived growth factor on inositol phospholipid turnover in NRK cellsStimulation of CD5 enhances signal transduction by the T cell antigen receptor.Ca2+-mobilizing actions of platelet-derived growth factor differ from those of bombesin and vasopressin in Swiss 3T3 mouse cells.Insulin-like synergistic stimulation of DNA synthesis in Swiss 3T3 cells by the BSC-1 cell-derived growth inhibitor related to transforming growth factor type betaGrowth factors, signaling pathways, and the regulation of proliferation and differentiation in BC3H1 muscle cells. II. Two signaling pathways distinguished by pertussis toxin and a potential role for the ras oncogene.From animal to molecule: aspects of the biology of insulin-like growth factorsNeuropeptides as cellular growth factors: role of multiple signalling pathways.Inositol 1,3,4,5-tetrakisphosphate and inositol hexakisphosphate receptor proteins: isolation and characterization from rat brain.Endothelial cell growth factor and ionophore A23187 stimulation of production of inositol phosphates in porcine aorta endothelial cells.Single-cell analysis of the mitogen-induced calcium responses of normal and protein kinase C-depleted Swiss 3T3 cells.Temporal relationship between inositol polyphosphate formation and increases in cytosolic Ca2+ in quiescent 3T3 cells stimulated by platelet-derived growth factor, bombesin and vasopressin.A tyrosine protein kinase activated by bombesin in normal fibroblasts and small cell carcinomas.Internalization and degradation of peptides of the bombesin family in Swiss 3T3 cells occurs without ligand-induced receptor down-regulation.Activation of AT1 angiotensin receptors induces DNA synthesis in a rat intestinal epithelial (RIE-1) cell line.Mastoparan, a novel mitogen for Swiss 3T3 cells, stimulates pertussis toxin-sensitive arachidonic acid release without inositol phosphate accumulationDifferential potentiation of mitogen-stimulated phosphoinositide hydrolysis in protein kinase C-depleted Swiss 3T3 cells.Bombesin receptor in membranes from Swiss 3T3 cells. Binding characteristics, affinity labelling and modulation by guanine nucleotides.Mass measurement of inositol 1,4,5-trisphosphate and sn-1,2-diacylglycerol in bombesin-stimulated Swiss 3T3 mouse fibroblasts.Bombesin and bombesin antagonists: studies in Swiss 3T3 cells and human small cell lung cancer.Metabolism of inositol bis-, tris-, tetrakis- and pentakis-phosphates in GH3 cells.Formation of inositol phosphate isomers in GH3 pituitary tumour cells stimulated with thyrotropin-releasing hormone. Acute effects of lithium ions.Granulocyte-macrophage colony-stimulating factor can stimulate macrophage proliferation via persistent activation of Na+/H+ antiport. Evidence for two distinct roles for Na+/H+ antiport activation.Regulation of bombesin-stimulated inositol 1,4,5-trisphosphate generation in Swiss 3T3 fibroblasts by a guanine-nucleotide-binding protein.Protein kinase C-mediated negative-feedback inhibition of unstimulated and bombesin-stimulated polyphosphoinositide hydrolysis in Swiss-mouse 3T3 cells.Bombesin, neuromedin B and neuromedin C interact with a common rat pancreatic phosphoinositide-coupled receptor, but are differentially regulated by guanine nucleotides.Rapid desensitization and resensitization of bombesin-stimulated phospholipase D activity in Swiss 3T3 cells.Stimulus-induced accumulation of inositol tetrakis-, pentakis-, and hexakisphosphates in N1E-115 neuroblastoma cells.Differential modulation of bombesin-stimulated phospholipase C beta and mitogen-activated protein kinase activity by [D-Arg1,D-Phe5,D-Trp7,9,Leu11]substance P.Rapid increase in inositol pentakisphosphate accumulation by nicotine in cultured adrenal chromaffin cells.The biphasic stimulation of insulin secretion by bombesin involves both cytosolic free calcium and protein kinase C.Modulation of bombesin-induced phosphatidylinositol hydrolysis in a small-cell lung-cancer cell line.Differential mechanisms of inositol phosphate generation at the receptors for bombesin and platelet-derived growth factorDifferential effects of platelet-derived growth factor, serum and bombesin on phospholipase D-mediated hydrolysis of phosphatidylethanolamine in NIH 3T3 fibroblasts.Bombesin and platelet-derived growth factor stimulate formation of inositol phosphates and Ca2+ mobilization in Swiss 3T3 cells by different mechanisms.Insulin-like growth factor 1 and insulin reduce epidermal growth factor binding to Swiss 3T3 cells by an indirect mechanism that is apparently independent of protein kinase C.Characterization of the high-affinity receptors on Swiss 3T3 cells which mediate the binding, internalization and degradation of the mitogenic peptide bombesin.Endothelin stimulates DNA synthesis in Swiss 3T3 cells. Synergy with polypeptide growth factors.Effects of pertussis toxin on growth factor-stimulated inositol phosphate formation and DNA synthesis in Swiss 3T3 cells.
P2860
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P2860
Effects of bombesin and insulin on inositol (1,4,5)trisphosphate and inositol (1,3,4)trisphosphate formation in Swiss 3T3 cells.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年学术文章
@wuu
1986年学术文章
@zh-cn
1986年学术文章
@zh-hans
1986年学术文章
@zh-my
1986年学术文章
@zh-sg
1986年學術文章
@yue
1986年學術文章
@zh
1986年學術文章
@zh-hant
name
Effects of bombesin and insuli ...... formation in Swiss 3T3 cells.
@en
Effects of bombesin and insuli ...... formation in Swiss 3T3 cells.
@nl
type
label
Effects of bombesin and insuli ...... formation in Swiss 3T3 cells.
@en
Effects of bombesin and insuli ...... formation in Swiss 3T3 cells.
@nl
prefLabel
Effects of bombesin and insuli ...... formation in Swiss 3T3 cells.
@en
Effects of bombesin and insuli ...... formation in Swiss 3T3 cells.
@nl
P2093
P1433
P1476
Effects of bombesin and insuli ...... formation in Swiss 3T3 cells.
@en
P2093
P304
P356
10.1016/0092-8674(86)90513-1
P407
P577
1986-12-01T00:00:00Z