COOH-terminal extended recombinant amphiregulin with bioactivity comparable with naturally derived growth factor.
about
A differential requirement for the COOH-terminal region of the epidermal growth factor (EGF) receptor in amphiregulin and EGF mitogenic signalingSelective roles for tumor necrosis factor alpha-converting enzyme/ADAM17 in the shedding of the epidermal growth factor receptor ligand family: the juxtamembrane stalk determines cleavage efficiency.Ultraviolet B-induced expression of amphiregulin and growth differentiation factor 15 in human lens epithelial cells.Binding to EGF receptor of a laminin-5 EGF-like fragment liberated during MMP-dependent mammary gland involution.Novel betacellulin derivatives. Separation of the differentiation activity from the mitogenic activity.Antisense expression for amphiregulin suppresses tumorigenicity of a transformed human breast epithelial cell line.Cell surface ectodomain cleavage of human amphiregulin precursor is sensitive to a metalloprotease inhibitor. Release of a predominant N-glycosylated 43-kDa soluble form.Amphiregulin antisense oligonucleotide inhibits the growth of T3M4 human pancreatic cancer cells and sensitizes the cells to EGF receptor-targeted therapy.Clarification of the C-terminal proteolytic processing site of human Amphiregulin.In vivo analysis of Argos structure-function. Sequence requirements for inhibition of the Drosophila epidermal growth factor receptor.
P2860
Q28139198-3EA7E2A6-6360-4B8B-990E-1E0DD1E42DEDQ33201079-763F5A96-AA5E-42E4-8F58-F2C226498DEBQ34493884-D8DE8928-46EA-42E2-8407-D35D51C6E9EFQ36323418-50C096B0-32A3-4162-BE31-A33B91AF6C2FQ38297450-9B2F02C2-B50E-4502-8650-E487F37B6413Q40912246-F70CB905-E34B-4B7A-A05C-85A07BAD3802Q41030490-4FE20E25-8B77-48BE-9DF8-460B592C0F39Q45958979-0C1C515B-8D24-4BED-9C55-91C6CC53A520Q46066628-386EC6C9-6CB7-4614-BBFD-0C2A4FF5FB18Q52189641-91E5D1DF-695A-465F-BA6E-4C665BA18DA0
P2860
COOH-terminal extended recombinant amphiregulin with bioactivity comparable with naturally derived growth factor.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
COOH-terminal extended recombi ...... turally derived growth factor.
@en
COOH-terminal extended recombi ...... turally derived growth factor.
@nl
type
label
COOH-terminal extended recombi ...... turally derived growth factor.
@en
COOH-terminal extended recombi ...... turally derived growth factor.
@nl
prefLabel
COOH-terminal extended recombi ...... turally derived growth factor.
@en
COOH-terminal extended recombi ...... turally derived growth factor.
@nl
P2093
P2860
P356
P1476
COOH-terminal extended recombi ...... turally derived growth factor.
@en
P2093
P2860
P304
17927-17931
P356
10.1074/JBC.271.30.17927
P407
P577
1996-07-01T00:00:00Z