Mitogenic signaling by Ret/ptc2 requires association with enigma via a LIM domain.
about
Ajuba, a novel LIM protein, interacts with Grb2, augments mitogen-activated protein kinase activity in fibroblasts, and promotes meiotic maturation of Xenopus oocytes in a Grb2- and Ras-dependent manner.Mystique is a new insulin-like growth factor-I-regulated PDZ-LIM domain protein that promotes cell attachment and migration and suppresses Anchorage-independent growthFine mapping of the alpha-actinin binding site within cysteine-rich proteinShc and Enigma are both required for mitogenic signaling by Ret/ptc2.Docking protein FRS2 links the protein tyrosine kinase RET and its oncogenic forms with the mitogen-activated protein kinase signaling cascadeGrb10, a positive, stimulatory signaling adapter in platelet-derived growth factor BB-, insulin-like growth factor I-, and insulin-mediated mitogenesisNuclear LIM interactor, a rhombotin and LIM homeodomain interacting protein, is expressed early in neuronal developmentEnigma interacts with adaptor protein with PH and SH2 domains to control insulin-induced actin cytoskeleton remodeling and glucose transporter 4 translocationNovel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiationProtein-protein interaction of zinc finger LIM domains with protein kinase CZRP-1, a zyxin-related protein, interacts with the second PDZ domain of the cytosolic protein tyrosine phosphatase hPTP1EIdentification of Grb10 as a direct substrate for members of the Src tyrosine kinase familyCLP-36 PDZ-LIM protein associates with nonmuscle alpha-actinin-1 and alpha-actinin-4Identification of a novel protein kinase A anchoring protein that binds both type I and type II regulatory subunitsEnigma prevents Cbl-c-mediated ubiquitination and degradation of RETMEN2AThe role of individual SH2 domains in mediating association of phospholipase C-gamma1 with the activated EGF receptorIdentification and characterization of genes upregulated in cells transformed by v-Jun.Inhibition of hGrb10 binding to the insulin receptor by functional domain-mediated oligomerization.Characterization of the human 36-kDa carboxyl terminal LIM domain protein (hCLIM1).Pdlim7 is required for maintenance of the mesenchymal/epidermal Fgf signaling feedback loop during zebrafish pectoral fin development.Phosphotyrosine 1062 is critical for the in vivo activity of the Ret9 receptor tyrosine kinase isoform.How familial cancer genes and environmentally induced oncogenes have changed the endocrine landscape.Mechanical stress-strain sensors embedded in cardiac cytoskeleton: Z disk, titin, and associated structures.The RET-glial cell-derived neurotrophic factor (GDNF) pathway stimulates migration and chemoattraction of epithelial cells.Specificity of LIM domain interactions with receptor tyrosine kinases.A targeting mutation of tyrosine 1062 in Ret causes a marked decrease of enteric neurons and renal hypoplasiaNucleocytoplasmic functions of the PDZ-LIM protein family: new insights into organ development.Exon Skipping in the RET Gene Encodes Novel Isoforms That Differentially Regulate RET Protein Signal Transduction.LIM domain protein-3 (LMP3) cooperates with BMP7 to promote tissue regeneration by ligament progenitor cellsVarious mechanisms cause RET-mediated signaling defects in Hirschsprung's disease.Engineering the recruitment of phosphotyrosine binding domain-containing adaptor proteins reveals distinct roles for RET receptor-mediated cell survival.The long and short isoforms of Ret function as independent signaling complexes.Coordinated activation of autophosphorylation sites in the RET receptor tyrosine kinase: importance of tyrosine 1062 for GDNF mediated neuronal differentiation and survival.Key role of Shc signaling in the transforming pathway triggered by Ret/ptc2 oncoprotein.The RFG oligomerization domain mediates kinase activation and re-localization of the RET/PTC3 oncoprotein to the plasma membrane.Differential effects of leukocyte common antigen-related protein on biochemical and biological activities of RET-MEN2A and RET-MEN2B mutant proteins.Signal transduction pathways activated by RET oncoproteins in PC12 pheochromocytoma cells.LMP1 regulates periodontal ligament progenitor cell proliferation and differentiation.LIM domains of cysteine-rich protein 1 (CRP1) are essential for its zyxin-binding function.Papillary thyroid carcinoma oncogene (RET/PTC) alters the nuclear envelope and chromatin structure.
P2860
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P2860
Mitogenic signaling by Ret/ptc2 requires association with enigma via a LIM domain.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Mitogenic signaling by Ret/ptc2 requires association with enigma via a LIM domain.
@en
Mitogenic signaling by Ret/ptc2 requires association with enigma via a LIM domain.
@nl
type
label
Mitogenic signaling by Ret/ptc2 requires association with enigma via a LIM domain.
@en
Mitogenic signaling by Ret/ptc2 requires association with enigma via a LIM domain.
@nl
prefLabel
Mitogenic signaling by Ret/ptc2 requires association with enigma via a LIM domain.
@en
Mitogenic signaling by Ret/ptc2 requires association with enigma via a LIM domain.
@nl
P2093
P2860
P356
P1476
Mitogenic signaling by Ret/ptc2 requires association with enigma via a LIM domain.
@en
P2093
P2860
P304
12691-12694
P356
10.1074/JBC.271.22.12691
P407
P577
1996-05-01T00:00:00Z