about
Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1Structural basis of the radicicol resistance displayed by a fungal hsp90Features of the Streptomyces hygroscopicus HtpG reveal how partial geldanamycin resistance can arise with mutation to the ATP binding pocket of a eukaryotic Hsp90A two-hybrid screen of the yeast proteome for Hsp90 interactors uncovers a novel Hsp90 chaperone requirement in the activity of a stress-activated mitogen-activated protein kinase, Slt2p (Mpk1p).Fab1p and AP-1 are required for trafficking of endogenously ubiquitylated cargoes to the vacuole lumen in S. cerevisiae.Qri2/Nse4, a component of the essential Smc5/6 DNA repair complex.Cdc37 engages in stable, S14A mutation-reinforced association with the most atypical member of the yeast kinome, Cdk-activating kinase (Cak1).Sensitivity to Hsp90-targeting drugs can arise with mutation to the Hsp90 chaperone, cochaperones and plasma membrane ATP binding cassette transporters of yeast.In the yeast heat shock response, Hsf1-directed induction of Hsp90 facilitates the activation of the Slt2 (Mpk1) mitogen-activated protein kinase required for cell integrity.Spotlight on the microbes that produce heat shock protein 90-targeting antibiotics.
P50
Q24337678-A653EBDF-18E7-4A1E-8D94-F00482A97C60Q27653888-AB0404EF-CE67-4431-B0F4-C3ABBC9C4AD2Q27670927-939D22E9-66AD-4CC0-88C5-D990D7791709Q27932386-52065AD3-D85A-4E2C-93E2-032FA9E70C4BQ27935472-7B42FC2C-2749-4AC0-830A-B106BAB4A082Q27938788-D7B9E870-778B-432D-AAEA-C615014CEC59Q34039633-E842934F-F816-4C03-B7E2-93ABCB31AD77Q34277193-14001561-8FC0-41DC-9A19-7EEAF600CFD6Q35783694-705CE4B9-9A3B-4ADC-9202-22D46DA42A16Q38070150-2E9E3F87-4CE7-4606-BD9A-2E84CAEE9FB5
P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Stefan Millson
@ast
Stefan Millson
@en
Stefan Millson
@es
Stefan Millson
@nl
Stefan Millson
@sl
type
label
Stefan Millson
@ast
Stefan Millson
@en
Stefan Millson
@es
Stefan Millson
@nl
Stefan Millson
@sl
prefLabel
Stefan Millson
@ast
Stefan Millson
@en
Stefan Millson
@es
Stefan Millson
@nl
Stefan Millson
@sl
P106
P21
P31
P496
0000-0001-5989-5759