PAK4 is required for regulation of the cell-cycle regulatory protein p21, and for control of cell-cycle progression.
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Group II p21-activated kinases as therapeutic targets in gastrointestinal cancerGL-1196 Suppresses the Proliferation and Invasion of Gastric Cancer Cells via Targeting PAK4 and Inhibiting PAK4-Mediated Signaling PathwaysP21-activated kinase 4 regulates the cyclin-dependent kinase inhibitor p57(kip2) in human breast cancerPAK signalling during the development and progression of cancerLC-0882 targets PAK4 and inhibits PAK4-related signaling pathways to suppress the proliferation and invasion of gastric cancer cells.p21-Activated Kinase 4 Promotes Intimal Hyperplasia and Vascular Smooth Muscle Cells Proliferation during Superficial Femoral Artery Restenosis after Angioplasty.Functional cooperativity by direct interaction between PAK4 and MMP-2 in the regulation of anoikis resistance, migration and invasion in gliomaDual and Specific Inhibition of NAMPT and PAK4 By KPT-9274 Decreases Kidney Cancer Growth.Anticystogenic activity of a small molecule PAK4 inhibitor may be a novel treatment for autosomal dominant polycystic kidney disease.Structure, biochemistry, and biology of PAK kinases.p-21 activated kinase 4 promotes proliferation and survival of pancreatic cancer cells through AKT- and ERK-dependent activation of NF-κB pathway.p53-facilitated miR-199a-3p regulates somatic cell reprogramming.Cross-talk between p21-activated kinase 4 and ERα signaling triggers endometrial cancer cell proliferation.Identification of the PAK4 interactome reveals PAK4 phosphorylation of N-WASP and promotion of Arp2/3-dependent actin polymerization.Inhibition of neuroblastoma proliferation by PF-3758309, a small-molecule inhibitor that targets p21-activated kinase 4.P21-activated kinase 4 (PAK4) is required for metaphase spindle positioning and anchoring.Role for p21-activated kinase PAK4 in development of the mammalian heart.DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery
P2860
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P2860
PAK4 is required for regulation of the cell-cycle regulatory protein p21, and for control of cell-cycle progression.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
PAK4 is required for regulatio ...... rol of cell-cycle progression.
@en
PAK4 is required for regulatio ...... rol of cell-cycle progression.
@nl
type
label
PAK4 is required for regulatio ...... rol of cell-cycle progression.
@en
PAK4 is required for regulatio ...... rol of cell-cycle progression.
@nl
prefLabel
PAK4 is required for regulatio ...... rol of cell-cycle progression.
@en
PAK4 is required for regulatio ...... rol of cell-cycle progression.
@nl
P2860
P356
P1476
PAK4 is required for regulatio ...... rol of cell-cycle progression.
@en
P2093
Audrey Minden
Tanya Nekrasova
P2860
P304
P356
10.1002/JCB.23092
P577
2011-07-01T00:00:00Z