Tumor necrosis factor receptor-associated factor 6 (TRAF6) associates with huntingtin protein and promotes its atypical ubiquitination to enhance aggregate formation.
about
Parkinson's disease DJ-1 L166P alters rRNA biogenesis by exclusion of TTRAP from the nucleolus and sequestration into cytoplasmic aggregates via TRAF6TRAF6 upregulation in spinal astrocytes maintains neuropathic pain by integrating TNF-α and IL-1β signalingLys29-linkage of ASK1 by Skp1-Cullin 1-Fbxo21 ubiquitin ligase complex is required for antiviral innate response.TRAF molecules in cell signaling and in human diseasesUbiqutination via K27 and K29 chains signals aggregation and neuronal protection of LRRK2 by WSB1.The Ubiquitination, Disaggregation and Proteasomal Degradation Machineries in Polyglutamine DiseaseCross-functional E3 ligases Parkin and C-terminus Hsp70-interacting protein in neurodegenerative disorders.Toward an integrative view of Optineurin functions.Ubiquitin pathways in neurodegenerative disease.Ubiquitination in disease pathogenesis and treatment.Degradation of mutant huntingtin via the ubiquitin/proteasome system is modulated by FE65.Polypharmacology of small molecules targeting the ubiquitin-proteasome and ubiquitin-like systems.SINEUPs are modular antisense long non-coding RNAs that increase synthesis of target proteins in cells.Network analysis of neurodegenerative disease highlights a role of Toll-like receptor signaling.Detection of ubiquitinated huntingtin species in intracellular aggregates.Protein phosphatase 1 regulates huntingtin exon 1 aggregation and toxicity.Tumor necrosis factor receptor-associated factor 6 participates in early brain injury after subarachnoid hemorrhage in rats through inhibiting autophagy and promoting oxidative stress.Dynamic recruitment of ubiquitin to mutant huntingtin inclusion bodies.TRAF molecules in inflammation and inflammatory diseases.Ubiquitin proteasome system networks in the neurological disorders
P2860
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P2860
Tumor necrosis factor receptor-associated factor 6 (TRAF6) associates with huntingtin protein and promotes its atypical ubiquitination to enhance aggregate formation.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Tumor necrosis factor receptor ...... o enhance aggregate formation.
@en
type
label
Tumor necrosis factor receptor ...... o enhance aggregate formation.
@en
prefLabel
Tumor necrosis factor receptor ...... o enhance aggregate formation.
@en
P2093
P2860
P50
P356
P1476
Tumor necrosis factor receptor ...... to enhance aggregate formation
@en
P2093
Alisia Carnemolla
Claudio Santoro
Elena Agostoni
Federica Marcuzzi
Francesca Persichetti
Marta Codrich
Sandra Vilotti
Stefano Gustincich
P2860
P304
25108-25117
P356
10.1074/JBC.M110.187591
P407
P577
2011-03-25T00:00:00Z