Effect of farnesyltransferase overexpression on cell growth and transformation.

about

Transcription factor BACH2 is transcriptionally regulated by the BCR/ABL oncogene.Inhibition of human tumor cell growth in vivo by an orally bioavailable inhibitor of human farnesyltransferase, BIM-46228.

P2860

Q34105380-E6FED327-12A0-4CDE-8D92-210D8A0F4370 Q42830828-519BBFDD-AB57-4171-8DE1-F29E3DF5FB5B

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Effect of farnesyltransferase overexpression on cell growth and transformation.

Item

http://www.wikidata.org/entity/Q42819840

description

1999 nî lūn-bûn

@nan

1999年の論文

@ja

1999年論文

@yue

1999年論文

@zh-hant

1999年論文

@zh-hk

1999年論文

@zh-mo

1999年論文

@zh-tw

1999年论文

@wuu

1999年论文

@zh

1999年论文

@zh-cn

name

Effect of farnesyltransferase overexpression on cell growth and transformation.

@en

Effect of farnesyltransferase overexpression on cell growth and transformation.

@nl

type

Item

label

Effect of farnesyltransferase overexpression on cell growth and transformation.

@en

Effect of farnesyltransferase overexpression on cell growth and transformation.

@nl

prefLabel

Effect of farnesyltransferase overexpression on cell growth and transformation.

@en

Effect of farnesyltransferase overexpression on cell growth and transformation.

@nl

P1476

Effect of farnesyltransferase overexpression on cell growth and transformation.

@en

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E Yamasaki

http://www.w3.org/2001/XMLSchema#string

H Nakajima

http://www.w3.org/2001/XMLSchema#string

I Matsumura

http://www.w3.org/2001/XMLSchema#string

J Miyagawa

http://www.w3.org/2001/XMLSchema#string

K Fukui

http://www.w3.org/2001/XMLSchema#string

K Yamamoto

http://www.w3.org/2001/XMLSchema#string

S Kawata

http://www.w3.org/2001/XMLSchema#string

S Tamura

http://www.w3.org/2001/XMLSchema#string

T Nagase

http://www.w3.org/2001/XMLSchema#string

Y Matsuda

http://www.w3.org/2001/XMLSchema#string

P2860

The p21(RAS) farnesyltransferase alpha subunit in TGF-beta and activin signaling

Cloning and expression of a cDNA encoding the alpha subunit of rat p21ras protein farnesyltransferase

pEF-BOS, a powerful mammalian expression vector

ras genes

High-performance liquid chromatographic assay for farnesyl-protein transferase activity with dabsylated peptide.

Isoprenoid addition to Ras protein is the critical modification for its membrane association and transforming activity

Evidence that farnesyltransferase inhibitors suppress Ras transformation by interfering with Rho activity.

MAP kinase kinase kinase, MAP kinase kinase and MAP kinase.

Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase I inhibitor in human tumor cell lines.

Interaction of transforming growth factor-beta receptor I with farnesyl-protein transferase-alpha in yeast and mammalian cells.

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126-133

http://www.w3.org/2001/XMLSchema#string

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scholarly article

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10.1002/(SICI)1097-0215(19990105)80:1<126::AID-IJC23>3.0.CO;2-U

http://www.w3.org/2001/XMLSchema#string

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http://www.w3.org/2001/XMLSchema#string

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http://www.w3.org/2001/XMLSchema#string

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1999-01-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

9935242

http://www.w3.org/2001/XMLSchema#string

P921

overexpression

Effect of farnesyltransferase overexpression on cell growth and transformation.

about

P2860

P2860

Effect of farnesyltransferase overexpression on cell growth and transformation.

description

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type

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prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P921

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P921