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Prion strain discrimination based on rapid in vivo amplification and analysis by the cell panel assayFirst demonstration of transmissible spongiform encephalopathy-associated prion protein (PrPTSE) in extracellular vesicles from plasma of mice infected with mouse-adapted variant Creutzfeldt-Jakob disease by in vitro amplification.In vitro generation of infectious scrapie prions.The N-terminal, polybasic region of PrP(C) dictates the efficiency of prion propagation by binding to PrP(Sc).Cell-free propagation of prion strains.Crossing the species barrier by PrP(Sc) replication in vitro generates unique infectious prions.Protein misfolding cyclic amplification (PMCA): Current status and future directions.Strain-specific role of RNAs in prion replicationGeneration of a new infectious recombinant prion: a model to understand Gerstmann-Sträussler-Scheinker syndrome.High-Resolution Single Particle Zeta Potential Characterisation of Biological Nanoparticles using Tunable Resistive Pulse Sensing.Ultra-efficient replication of infectious prions by automated protein misfolding cyclic amplification.Presymptomatic detection of prions in blood.Pre-symptomatic detection of prions by cyclic amplification of protein misfolding.Is sporadic Creutzfeldt-Jakob disease transfusion-transmissible?Acute Zika virus infection in an asymptomatic blood donor at the onset of the Puerto Rico epidemicQualification of the Geenius HIV 1/2 supplemental assay for use in the HIV blood donation screening algorithm
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P106
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8851950200
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0000-0001-6077-4532