Signaling requirements for oncogenic forms of the Met tyrosine kinase receptor.
about
Use of signal specific receptor tyrosine kinase oncoproteins reveals that pathways downstream from Grb2 or Shc are sufficient for cell transformation and metastasisMet receptor tyrosine kinase: enhanced signaling through adapter proteinsDirect binding of the signaling adapter protein Grb2 to the activation loop tyrosines on the nerve growth factor receptor tyrosine kinase, TrkAThe tyrosine phosphatase SHP-2 is required for sustained activation of extracellular signal-regulated kinase and epithelial morphogenesis downstream from the met receptor tyrosine kinase.Germline met mutations in mice reveal mutation- and background-associated differences in tumor profiles.Enhanced transformation by a plasma membrane-associated met oncoprotein: activation of a phosphoinositide 3'-kinase-dependent autocrine loop involving hyaluronic acid and CD44.Suppression of human colon tumor growth by adenoviral vector-mediated NK4 expression in an athymic mouse modelDysregulation of Met receptor tyrosine kinase activity in invasive tumorsExpression of c-Met and heparan-sulfate proteoglycan forms of CD44 in colorectal cancerCurrent understanding of the molecular mechanisms of kidney cancer: a primer for urologists.Progesterone receptor A and c-Met mediates spheroids-endometrium attachmentRole of cMET in the development and progression of colorectal cancerAbsence of tpr-met and expression of c-met in human gastric mucosa and carcinoma.Potent blockade of hepatocyte growth factor-stimulated cell motility, matrix invasion and branching morphogenesis by antagonists of Grb2 Src homology 2 domain interactions.The proto-oncogene c-Cbl is a positive regulator of Met-induced MAP kinase activation: a role for the adaptor protein Crk.Comment on "Effect of transferred NK4 gene on proliferation, migration, invasion, and apoptosis of human prostate cancer DU145 cells" by Dan Yue et al. in Asian Journal of Andrology.Tumorigenesis mediated by MET mutant M1268T is inhibited by dominant-negative Src.Activating mutations in the Met receptor overcome the requirement for autophosphorylation of tyrosines crucial for wild type signaling.Structural basis of oncogenic activation caused by point mutations in the kinase domain of the MET proto-oncogene: modeling studies.
P2860
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P2860
Signaling requirements for oncogenic forms of the Met tyrosine kinase receptor.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Signaling requirements for oncogenic forms of the Met tyrosine kinase receptor.
@en
Signaling requirements for oncogenic forms of the Met tyrosine kinase receptor.
@nl
type
label
Signaling requirements for oncogenic forms of the Met tyrosine kinase receptor.
@en
Signaling requirements for oncogenic forms of the Met tyrosine kinase receptor.
@nl
prefLabel
Signaling requirements for oncogenic forms of the Met tyrosine kinase receptor.
@en
Signaling requirements for oncogenic forms of the Met tyrosine kinase receptor.
@nl
P2093
P356
P1433
P1476
Signaling requirements for oncogenic forms of the Met tyrosine kinase receptor
@en
P2093
Fiscella M
Sathyanarayana BK
Vande Woude GF
P2888
P304
P356
10.1038/SJ.ONC.1202209
P407
P577
1998-11-01T00:00:00Z
P6179
1048339733