Intracellular delivery of phosphatidylinositol (3,4,5)-trisphosphate causes incorporation of glucose transporter 4 into the plasma membrane of muscle and fat cells without increasing glucose uptake.
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Insulin stimulates phosphatidylinositol 3-phosphate production via the activation of Rab5HIV gp41 engages gC1qR on CD4+ T cells to induce the expression of an NK ligand through the PIP3/H2O2 pathway.Spatiotemporal Regulators for Insulin-Stimulated GLUT4 Vesicle Exocytosis.Phosphoinositide 3-kinases upregulate system xc(-) via eukaryotic initiation factor 2α and activating transcription factor 4 - A pathway active in glioblastomas and epilepsyThe many ways to regulate glucose transporter 4.NOD1 activators link innate immunity to insulin resistanceIdentification of P-Rex1 as a novel Rac1-guanine nucleotide exchange factor (GEF) that promotes actin remodeling and GLUT4 protein trafficking in adipocytesTurning signals on and off: GLUT4 traffic in the insulin-signaling highway.Cardiac PI3K-Akt impairs insulin-stimulated glucose uptake independent of mTORC1 and GLUT4 translocation."Actin"g on GLUT4: membrane & cytoskeletal components of insulin action.Phosphatidylinositol 4,5-bisphosphate reverses endothelin-1-induced insulin resistance via an actin-dependent mechanismPhosphoinositides in insulin action on GLUT4 dynamics: not just PtdIns(3,4,5)P3.Optogenetic activation reveals distinct roles of PIP3 and Akt in adipocyte insulin action.Hesperetin impairs glucose uptake and inhibits proliferation of breast cancer cells.Lipotoxic disruption of NHE1 interaction with PI(4,5)P2 expedites proximal tubule apoptosis.Insulin and hypertonicity recruit GLUT4 to the plasma membrane of muscle cells by using N-ethylmaleimide-sensitive factor-dependent SNARE mechanisms but different v-SNAREs: role of TI-VAMP.Phosphatidylinositol 3-phosphate [PtdIns3P] is generated at the plasma membrane by an inositol polyphosphate 5-phosphatase: endogenous PtdIns3P can promote GLUT4 translocation to the plasma membrane.Activation of survival and apoptotic signaling pathways in lymphocytes exposed to palmitic acid.5-Stabilized phosphatidylinositol 3,4,5-trisphosphate analogues bind Grp1 PH, inhibit phosphoinositide phosphatases, and block neutrophil migration.Malonyl coenzyme A affects insulin-stimulated glucose transport in myotubes.Glucose-dependent insulinotropic polypeptide directly induces glucose transport in rat skeletal muscle.Synthesis and biological activity of PTEN-resistant analogues of phosphatidylinositol 3,4,5-trisphosphate.Calcium signaling recruits substrate transporters GLUT4 and CD36 to the sarcolemma without increasing cardiac substrate uptake.AMP kinase activation and glut4 translocation in isolated cardiomyocytesPolymeric carrier-mediated intracellular delivery of phosphatidylinositol-3,4,5-trisphosphate to overcome insulin resistance.Synthesis and biological activity of phosphatidylinositol-3,4,5-trisphosphorothioate.Insulin regulates the membrane arrival, fusion, and C-terminal unmasking of glucose transporter-4 via distinct phosphoinositides.
P2860
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P2860
Intracellular delivery of phosphatidylinositol (3,4,5)-trisphosphate causes incorporation of glucose transporter 4 into the plasma membrane of muscle and fat cells without increasing glucose uptake.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Intracellular delivery of phos ...... out increasing glucose uptake.
@en
Intracellular delivery of phos ...... out increasing glucose uptake.
@nl
type
label
Intracellular delivery of phos ...... out increasing glucose uptake.
@en
Intracellular delivery of phos ...... out increasing glucose uptake.
@nl
prefLabel
Intracellular delivery of phos ...... out increasing glucose uptake.
@en
Intracellular delivery of phos ...... out increasing glucose uptake.
@nl
P2093
P2860
P356
P1476
Intracellular delivery of phos ...... out increasing glucose uptake.
@en
P2093
Gary Sweeney
Glenn D Prestwich
Leonard J Foster
Manabu Ishiki
Paul O Neilsen
Rami R Garg
Rolando B Ceddia
Romel Somwar
P2860
P304
32233-32242
P356
10.1074/JBC.M402897200
P407
P577
2004-05-27T00:00:00Z