Inhibitors of HGFA, Matriptase, and Hepsin Serine Proteases: A Nonkinase Strategy to Block Cell Signaling in Cancer.
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Type II transmembrane serine proteases as potential targets for cancer therapy.Design and Synthesis of Nonpeptide Inhibitors of Hepatocyte Growth Factor Activation.α-Ketobenzothiazole Serine Protease Inhibitors of Aberrant HGF/c-MET and MSP/RON Kinase Pathway Signaling in Cancer.Hepatocyte Growth Factor, a Key Tumor-Promoting Factor in the Tumor Microenvironment.The role of type II transmembrane serine protease-mediated signaling in cancer.Human airway trypsin-like protease, a serine protease involved in respiratory diseases.Inhibition of pro-HGF activation by SRI31215, a novel approach to block oncogenic HGF/MET signaling.Limiting the Number of Potential Binding Modes by Introducing Symmetry into Ligands: Structure-Based Design of Inhibitors for Trypsin-Like Serine Proteases.Changing the selectivity profile - from substrate analog inhibitors of thrombin and factor Xa to potent matriptase inhibitors.
P2860
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P2860
Inhibitors of HGFA, Matriptase, and Hepsin Serine Proteases: A Nonkinase Strategy to Block Cell Signaling in Cancer.
description
2014 nî lūn-bûn
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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2014年论文
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name
Inhibitors of HGFA, Matriptase ...... lock Cell Signaling in Cancer.
@en
Inhibitors of HGFA, Matriptase ...... lock Cell Signaling in Cancer.
@nl
type
label
Inhibitors of HGFA, Matriptase ...... lock Cell Signaling in Cancer.
@en
Inhibitors of HGFA, Matriptase ...... lock Cell Signaling in Cancer.
@nl
prefLabel
Inhibitors of HGFA, Matriptase ...... lock Cell Signaling in Cancer.
@en
Inhibitors of HGFA, Matriptase ...... lock Cell Signaling in Cancer.
@nl
P2093
P2860
P50
P356
P1476
Inhibitors of HGFA, Matriptase ...... lock Cell Signaling in Cancer.
@en
P2093
Manjula Agarwal
Peter K W Harris
Ryan Chugani
Zhenfu Han
P2860
P304
P356
10.1021/ML500254R
P577
2014-10-09T00:00:00Z