about
SIRT2 induces the checkpoint kinase BubR1 to increase lifespanSIRT4 represses peroxisome proliferator-activated receptor α activity to suppress hepatic fat oxidationHigh-Resolution Crystal Structures of Streptococcus pneumoniae Nicotinamidase with Trapped Intermediates Provide Insights into the Catalytic Mechanism and Inhibition by Aldehydes,Characterization of nicotinamidases: steady state kinetic parameters, classwide inhibition by nicotinaldehydes, and catalytic mechanism.Global analysis of transcriptional regulation by poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase in MCF-7 human breast cancer cellsNicotinamide N-methyltransferase knockdown protects against diet-induced obesity.Advances in characterization of human sirtuin isoforms: chemistries, targets and therapeutic applications.PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activationPARP-2 regulates SIRT1 expression and whole-body energy expenditureMechanism-based affinity capture of sirtuinsGlucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of NamptThe NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity.Sirtuins inhibitors: the approach to affinity and selectivity.Transition state of ADP-ribosylation of acetyllysine catalyzed by Archaeoglobus fulgidus Sir2 determined by kinetic isotope effects and computational approachesDiastereocontrolled electrophilic fluorinations of 2-deoxyribonolactone: syntheses of all corresponding 2-deoxy-2-fluorolactones and 2'-deoxy-2'-fluoro-NAD+sEfficient syntheses of clofarabine and gemcitabine from 2-deoxyribonolactone.Trichostatin A inhibits deacetylation of histone H3 and p53 by SIRT6.Development of Activity-Based Chemical Probes for Human Sirtuins.Chemo-enzymatic synthesis of isotopically labeled nicotinamide ribosideScalable Synthesis and Purification of Acetylated Phosphatidyl Choline Headgroup.Polarity of Hydrated Phosphatidylcholine Headgroups
P50
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P50
description
hulumtuese
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Yana Cen
@ast
Yana Cen
@en
Yana Cen
@es
Yana Cen
@nl
Yana Cen
@sl
type
label
Yana Cen
@ast
Yana Cen
@en
Yana Cen
@es
Yana Cen
@nl
Yana Cen
@sl
prefLabel
Yana Cen
@ast
Yana Cen
@en
Yana Cen
@es
Yana Cen
@nl
Yana Cen
@sl
P1053
F-4731-2014
P106
P1153
24170758000
P21
P31
P3829
P496
0000-0001-6436-5744