about
Insulin receptor substrate 2 (IRS2)-deficient mice show sensorineural hearing loss that is delayed by concomitant protein tyrosine phosphatase 1B (PTP1B) loss of functionNormal proliferation and tumorigenesis but impaired pancreatic function in mice lacking the cell cycle regulator sei1.Protein Tyrosine Phosphatase 1B (PTP1B) deficiency accelerates hepatic regeneration in miceProtein tyrosine phosphatase 1B modulates GSK3β/Nrf2 and IGFIR signaling pathways in acetaminophen-induced hepatotoxicity.Increased oxidative stress and apoptosis in the hypothalamus of diabetic male mice in the insulin receptor substrate-2 knockout model.Pivotal role of protein tyrosine phosphatase 1B (PTP1B) in the macrophage response to pro-inflammatory and anti-inflammatory challenge.Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD.IRS2 and PTP1B: Two opposite modulators of hepatic insulin signalling.IL-6 cooperates with peroxisome proliferator-activated receptor-α-ligands to induce liver fatty acid binding protein (LFABP) up-regulation.Essential role of protein-tyrosine phosphatase 1B in the modulation of insulin signaling by acetaminophen in hepatocytes.Azathioprine desensitizes liver cancer cells to insulin-like growth factor 1 and causes apoptosis when it is combined with bafilomycin A1.Studies of naturally occurring friedelane triterpenoids as insulin sensitizers in the treatment type 2 diabetes mellitus.Protein-tyrosine phosphatase 1B (PTP1B) deficiency confers resistance to transforming growth factor-β (TGF-β)-induced suppressor effects in hepatocytesBeneficial effects of fenofibrate in retinal pigment epithelium by the modulation of stress and survival signaling under diabetic conditions.Hepatic insulin resistance is associated with increased apoptosis and fibrogenesis in nonalcoholic steatohepatitis and chronic hepatitis C.Impairment of transforming growth factor beta signaling in caveolin-1-deficient hepatocytes: role in liver regeneration.Topical administration of somatostatin prevents retinal neurodegeneration in experimental diabetes.PTP1B deficiency increases glucose uptake in neonatal hepatocytes: involvement of IRA/GLUT2 complexes.Beneficial effects of PTP1B deficiency on brown adipocyte differentiation and protection against apoptosis induced by pro- and anti-inflammatory stimuli.In vivo siRNA delivery of Keap1 modulates death and survival signaling pathways and attenuates concanavalin-A-induced acute liver injury in mice.PTP1B deficiency enhances liver growth during suckling by increasing the expression of insulin-like growth factor-I.CHOP is a critical regulator of acetaminophen-induced hepatotoxicity.Eukaryotic elongation factor 2 controls TNF-α translation in LPS-induced hepatitis.Hepatic cyclooxygenase-2 expression protects against diet-induced steatosis, obesity, and insulin resistance.Differential insulin receptor substrate-1 (IRS1)-related modulation of neuropeptide Y and proopiomelanocortin expression in nondiabetic and diabetic IRS2-/- mice.Loss of protein tyrosine phosphatase 1B increases IGF-I receptor tyrosine phosphorylation but does not rescue retinal defects in IRS2-deficient mice.Liver-specific insulin receptor isoform A expression enhances hepatic glucose uptake and ameliorates liver steatosis in a mouse model of diet-induced obesity
P50
Q30468589-6337981B-912D-4237-86AC-CE7AA56B46EDQ33525540-0B90490D-A195-4664-B791-6E3472B7D22CQ34805653-C2ABD91E-AEC7-469A-A985-42A073AE4EC5Q36907101-E59F16FC-2F59-4BDD-B4B8-B1AA7F00BD24Q36967517-174FE56B-697A-4C85-ADEA-EFB18031AF56Q37680231-DF328F6E-BCE0-4CD6-9D19-63FBF658F46DQ37726154-2E6DDB61-3702-424D-B3FE-B43690614001Q37852704-1BB782C9-47B4-4AD8-BDFC-2DE58FB445EFQ38316712-9124E94B-ADFA-48A4-9F37-89026C8ED89FQ38958076-AD40484B-A14F-4727-8A3F-740BC2C0537AQ39108249-FF37836A-875F-468E-BBFF-7D84B587A796Q39290238-BE425C50-91B3-4DB3-91A4-6D5AA4C66AD2Q39377565-4B433B54-3FB8-44E3-9A06-DB28C6DD7D28Q39493020-635626DF-B725-45C5-BAC1-D2A93D22752FQ39648890-EAA22206-F5D4-4232-AADC-7499128B6B62Q39766282-81BD8A7C-57EB-41EB-BEC4-549B3801AAE5Q42084102-D21EA433-9B72-4696-A27A-C6169C871C00Q42437089-EC80EF6E-0627-4F72-A2EA-656E75BAC349Q42464719-E3475687-7D57-4B02-BEC1-776D01AC9A78Q42837335-6A120A40-E921-4408-9800-2A8B16A07D98Q43053153-FECE07C6-9232-46A3-81F1-F1338CA73F2AQ44693987-2BC9A5FA-7DB2-4F62-AF6C-188751BC7846Q46278773-7B593DCD-804C-4BA8-BBEB-20838B9607B9Q46525580-1F31F07F-27ED-4862-AEB8-975A9DD0A828Q48735096-7E59746F-0EDD-427B-8EB4-2D094EA1A002Q50965366-CE738CBC-9DC5-4B90-B256-28D9A526140DQ64236016-C7E5D667-4C9E-4659-AF26-8AB8DA84082B
P50
description
hulumtuese
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Agueda Gonzalez-rodriguez
@ast
Agueda Gonzalez-rodriguez
@en
Agueda Gonzalez-rodriguez
@es
Agueda Gonzalez-rodriguez
@nl
type
label
Agueda Gonzalez-rodriguez
@ast
Agueda Gonzalez-rodriguez
@en
Agueda Gonzalez-rodriguez
@es
Agueda Gonzalez-rodriguez
@nl
prefLabel
Agueda Gonzalez-rodriguez
@ast
Agueda Gonzalez-rodriguez
@en
Agueda Gonzalez-rodriguez
@es
Agueda Gonzalez-rodriguez
@nl
P1053
D-7651-2012
P106
P21
P31
P3829
P496
0000-0001-6559-0847