The Toll-like receptor adaptor proteins MyD88 and Mal/TIRAP contribute to the inflammatory and destructive processes in a human model of rheumatoid arthritis.
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Regulatory Role of IL-1R8 in Immunity and DiseasePattern recognition receptors as potential therapeutic targets in inflammatory rheumatic diseaseA comprehensive molecular interaction map for rheumatoid arthritis.Chondrocyte innate immune myeloid differentiation factor 88-dependent signaling drives procatabolic effects of the endogenous Toll-like receptor 2/Toll-like receptor 4 ligands low molecular weight hyaluronan and high mobility group box chromosomal pToll-like receptor 2 induced angiogenesis and invasion is mediated through the Tie2 signalling pathway in rheumatoid arthritis.Toll-like receptor signaling: a potential link among rheumatoid arthritis, systemic lupus, and atherosclerosis.Potent anti-inflammatory effects of the narrow spectrum kinase inhibitor RV1088 on rheumatoid arthritis synovial membrane cells.Developing the next generation of monoclonal antibodies for the treatment of rheumatoid arthritis.Spontaneous insertion of a b2 element in the ptpn6 gene drives a systemic autoinflammatory disease in mice resembling neutrophilic dermatosis in humansNon-essential role for TLR2 and its signaling adaptor Mal/TIRAP in preserving normal lung architecture in miceThe role of TLR4 activation in photoreceptor mitochondrial oxidative stressCytosolic phospholipase A2 modulates TLR2 signaling in synoviocytesBlockade of Toll-like receptor 2 prevents spontaneous cytokine release from rheumatoid arthritis ex vivo synovial explant culturesRegulation of reactionary dentin formation by odontoblasts in response to polymicrobial invasion of dentin matrix.Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1β production via NRF2-mediated counter-regulation of the inflammasomeToll-like receptor 2 (TLR2) induces migration and invasive mechanisms in rheumatoid arthritis.Toll/interleukin-1 receptor domain dimers as the platform for activation and enhanced inhibition of Toll-like receptor signaling.14-3-3ε and 14-3-3σ inhibit Toll-like receptor (TLR)-mediated proinflammatory cytokine induction.Suppression of TLR signaling by targeting TIR domain-containing proteinsMRP8 promotes Th17 differentiation via upregulation of IL-6 production by fibroblast-like synoviocytes in rheumatoid arthritis.Targeting toll-like receptors for drug development: a summary of commercial approaches.Cell signalling in macrophages, the principal innate immune effector cells of rheumatoid arthritis.Antigen-specific tolerogenic and immunomodulatory strategies for the treatment of autoimmune arthritis.Toll/Interleukin-1 Receptor Domain Derived from TcpC (TIR-TcpC) Ameliorates Experimental Autoimmune Arthritis by Down-modulating Th17 Cell Response.Targeting intracellular signaling: a novel approach to vaccination.Release of heat shock protein 70 and the effects of extracellular heat shock protein 70 on the production of IL-10 in fibroblast-like synoviocytes.Candida albicans induces cyclo-oxygenase 2 expression and prostaglandin E2 production in synovial fibroblasts through an extracellular-regulated kinase 1/2 dependent pathwayAnalyses of synovial tissues from arthritic and protected congenic rat strains reveal a new core set of genes associated with disease severityCurrent concepts in the pathogenesis of early rheumatoid arthritis.Toll gates to periodontal host modulation and vaccine therapyTargeting Innate Immunity for CV Benefit.The role of toll-like receptors in rheumatoid arthritisToll-like receptors and NOD-like receptors in rheumatic diseases.IL-29 enhances Toll-like receptor-mediated IL-6 and IL-8 production by the synovial fibroblasts from rheumatoid arthritis patients.Endogenous toll-like receptor ligands and their biological significance.Modulation of toll-like receptor function has therapeutic potential in autoimmune disease.Toll-like receptor signaling: common pathways that drive cardiovascular disease and rheumatoid arthritis.Intrinsic danger: activation of Toll-like receptors in rheumatoid arthritis.Emerging role of endosomal toll-like receptors in rheumatoid arthritisPound the alarm: danger signals in rheumatic diseases.
P2860
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P2860
The Toll-like receptor adaptor proteins MyD88 and Mal/TIRAP contribute to the inflammatory and destructive processes in a human model of rheumatoid arthritis.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
The Toll-like receptor adaptor ...... model of rheumatoid arthritis.
@en
The Toll-like receptor adaptor ...... model of rheumatoid arthritis.
@nl
type
label
The Toll-like receptor adaptor ...... model of rheumatoid arthritis.
@en
The Toll-like receptor adaptor ...... model of rheumatoid arthritis.
@nl
prefLabel
The Toll-like receptor adaptor ...... model of rheumatoid arthritis.
@en
The Toll-like receptor adaptor ...... model of rheumatoid arthritis.
@nl
P2093
P2860
P1476
The Toll-like receptor adaptor ...... model of rheumatoid arthritis.
@en
P2093
Anna Lundberg
Brian M Foxwell
Evangelos Andreakos
Fionula Brennan
Grey Giddins
Marc Feldmann
Parisa Amjadi
Serafim Kiriakidis
P2860
P304
P356
10.2353/AJPATH.2007.060657
P407
P577
2007-02-01T00:00:00Z