Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease
about
Early B-cell Factor gene association with multiple sclerosis in the Spanish population.Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondriaRBM4 interacts with an intronic element and stimulates tau exon 10 inclusionMARK4 is a novel microtubule-associated proteins/microtubule affinity-regulating kinase that binds to the cellular microtubule network and to centrosomesNovel complex integrating mitochondria and the microtubular cytoskeleton with chromosome remodeling and tumor suppressor RASSF1 deduced by in silico homology analysis, interaction cloning in yeast, and colocalization in cultured cellsProtein kinase MARK/PAR-1 is required for neurite outgrowth and establishment of neuronal polarity.Amyloid-β oligomers induce synaptic damage via Tau-dependent microtubule severing by TTLL6 and spastinHUMMR, a hypoxia- and HIF-1alpha-inducible protein, alters mitochondrial distribution and transportPhosphorylation controls CLIMP-63-mediated anchoring of the endoplasmic reticulum to microtubulesPAK5 kinase is an inhibitor of MARK/Par-1, which leads to stable microtubules and dynamic actin.Two splice variants of Golgi-microtubule-associated protein of 210 kDa (GMAP-210) differ in their binding to the cis-Golgi networkAn intimate liaison: spatial organization of the endoplasmic reticulum-mitochondria relationshipRat kinesin light chain 3 associates with spermatid mitochondriaUXT (Ubiquitously Expressed Transcript) causes mitochondrial aggregationNicotinamide restores cognition in Alzheimer's disease transgenic mice via a mechanism involving sirtuin inhibition and selective reduction of Thr231-phosphotauSpred1 and TESK1--two new interaction partners of the kinase MARKK/TAO1 that link the microtubule and actin cytoskeletonHyperphosphorylation of microtubule-associated protein tau: a promising therapeutic target for Alzheimer diseaseMAP2 and tau bind longitudinally along the outer ridges of microtubule protofilamentsThe MAP2/Tau family of microtubule-associated proteinsGlial Tau Pathology in Tauopathies: Functional ConsequencesCritical pathogenic events underlying progression of neurodegeneration in glaucomaSuccessful therapies for Alzheimer's disease: why so many in animal models and none in humans?Targeting Hsp90/Hsp70-based protein quality control for treatment of adult onset neurodegenerative diseasesMitochondrial abnormalities in Alzheimer's disease: possible targets for therapeutic interventionThe role of tau in neurodegenerative diseases and its potential as a therapeutic targetThe axonal transport of mitochondriaTau and tauopathiesSpatially-resolved intracellular sensing of hydrogen peroxide in living cellsFunctional Impact of Corticotropin-Releasing Factor Exposure on Tau Phosphorylation and Axon TransportDisruption of mitochondrial DNA replication in Drosophila increases mitochondrial fast axonal transport in vivoEvidence for the involvement of KIF4 in the anterograde transport of L1-containing vesiclesBlood biomarkers for brain injury: What are we measuring?Tau physiology and pathomechanisms in frontotemporal lobar degenerationThe Dark Matter of BiologyA Case for Microtubule Vulnerability in Amyotrophic Lateral Sclerosis: Altered Dynamics During DiseaseTau accumulation causes mitochondrial distribution deficits in neurons in a mouse model of tauopathy and in human Alzheimer's disease brainTau promotes neurodegeneration via DRP1 mislocalization in vivoComparative biochemistry of tau in progressive supranuclear palsy, corticobasal degeneration, FTDP-17 and Pick's diseaseSubcellular distribution, calmodulin interaction, and mitochondrial association of the hyaluronan-binding protein RHAMM in rat brainThe Ubiquitin-Proteasome System and Molecular Chaperone Deregulation in Alzheimer's Disease
P2860
Q21261385-4C2C57BC-9723-4601-A315-B78061A00EAAQ21563375-0336561A-DCD8-43AF-94F5-8CBD25CD2B62Q24293631-1F106CE5-DF81-41AD-9D9C-311E7F64F052Q24299072-ED62E665-C5D9-48D4-9FE5-2BBDB6767EA0Q24302341-91E7043D-CEF2-4535-9D2E-A6E9B358A621Q24317775-297AB361-079F-4D2F-A9B0-E98C47C01536Q24337233-4FB23FC7-6328-4910-BB9C-5625A629CBA9Q24338481-71C83430-1D77-43DC-860F-085E3FD815A0Q24521373-E90D4A40-9D99-409F-A2E7-5C01F1B98BB4Q24530623-F15435D2-C4C4-4ABA-9554-4CD93CBE7B9DQ24533365-9653D70B-936F-4120-AEB5-D0B4EBA87881Q24630079-50696F59-974E-4E96-8D71-EE324A0651D4Q24632243-DE113C59-2C1C-46A6-AC53-26D4D5F4B831Q24632888-9FC88668-7DE3-4FCB-B845-EBAE2ADD151FQ24651880-C6646AC1-6C53-48A5-B685-44E75DEBFD18Q24656932-994349F8-6B05-4401-9775-5C76BCBC3A7FQ24657243-D83FCF52-2BEB-457E-8113-D3F57FAA2394Q24672581-06180CD2-D86F-40FD-8A21-27ACF5BEB0C4Q24805413-E6990E7E-143F-40EE-B97F-9C10358A7697Q26765365-1791CCA9-6F0F-49BB-9662-3DCA1C3954E1Q26859194-9034F8FE-61A1-4C40-B61C-0076DF176A86Q26859305-653407E2-A395-43AB-90CF-B3B041C5EDF0Q26859909-EEE97B0B-72F8-410B-8FEE-C78F2FC8F6AFQ26865358-659EDC8D-ED46-4A77-BF43-9F21720C6542Q27005032-C80DABD7-EA65-4108-B3CB-08DE8112D432Q27007553-AD3D1286-5D46-4006-B98F-8EDE3D16F946Q27027415-D6A7B4C4-0A7A-47B7-8120-D79F4925925AQ27305361-552ED11C-1568-4EC8-8306-53CCC9175D08Q27329404-D12A729A-8761-4F2B-9113-E4E7EF5A9F10Q27335303-8B19CD54-1B94-435D-BBD6-9790EE5B72C0Q27863665-532B253E-FFAA-4DD2-A08A-60ECD183DFDAQ28067275-C85F7AA7-F3D4-4C41-9618-EF87EAF7CC93Q28070250-2A7211DF-4CAB-4AF9-9C95-F6E7DFD09E3FQ28076983-5AD408DE-711A-4B17-A229-BD3CB9E91531Q28079299-A5E46A98-86FD-4884-A212-9D6DDC4A01CCQ28116593-EC05241E-DE4A-45FB-8004-6CC971A57DD5Q28119104-0BB840BD-16EC-4A82-9A3C-7C268D7CCBB4Q28145739-469D9BFC-2F41-470F-8C5D-3A8C1E9A2C2BQ28204390-375CF265-CA7F-4DA9-B5CD-8D40CE1503C4Q28254943-DC7A0EE2-572C-4BD3-81C3-CE1B0A412A2D
P2860
Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implications for Alzheimer's disease
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Overexpression of tau protein ...... ations for Alzheimer's disease
@en
Overexpression of tau protein ...... ations for Alzheimer's disease
@nl
type
label
Overexpression of tau protein ...... ations for Alzheimer's disease
@en
Overexpression of tau protein ...... ations for Alzheimer's disease
@nl
prefLabel
Overexpression of tau protein ...... ations for Alzheimer's disease
@en
Overexpression of tau protein ...... ations for Alzheimer's disease
@nl
P2093
P2860
P921
P356
P1476
Overexpression of tau protein ...... ations for Alzheimer's disease
@en
P2093
B Trinczek
E Mandelkow
R Godemann
S Illenberger
P2860
P304
P356
10.1083/JCB.143.3.777
P407
P577
1998-11-01T00:00:00Z