A rare mutation of CACNA1C in a patient with bipolar disorder, and decreased gene expression associated with a bipolar-associated common SNP of CACNA1C in brain.
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Genetics of bipolar disorderGenetic disruption of voltage-gated calcium channels in psychiatric and neurological disordersMolecular neurobiological clues to the pathogenesis of bipolar disorderEthical and public policy challenges for pharmacogenomicsA role for noncoding variation in schizophreniaMolecular network analysis enhances understanding of the biology of mental disorders.Functional implications of a psychiatric risk variant within CACNA1C in induced human neuronsDysregulation of miR-34a links neuronal development to genetic risk factors for bipolar disorder.Targeting the schizophrenia genome: a fast track strategy from GWAS to clinic.Functional Characterization of Schizophrenia-Associated Variation in CACNA1C.Sex-dependent modulation of age-related cognitive decline by the L-type calcium channel gene Cacna1c (Cav 1.2)Calcium channel genes associated with bipolar disorder modulate lithium's amplification of circadian rhythms.Arrhythmogenesis in Timothy Syndrome is associated with defects in Ca(2+)-dependent inactivationCACNA1C hypermethylation is associated with bipolar disorder.Targeting voltage-gated calcium channels in neurological and psychiatric diseases.CACNA1C polymorphisms Impact Cognitive Recovery in Patients with Bipolar Disorder in a Six-week Open-label Trial.Rescue of impaired sociability and anxiety-like behavior in adult cacna1c-deficient mice by pharmacologically targeting eIF2α.L-type Ca2+ channels in mood, cognition and addiction: integrating human and rodent studies with a focus on behavioural endophenotypes.Molecular mechanisms underlying noncoding risk variations in psychiatric genetic studiesThe impact of CACNA1C gene, and its epistasis with ZNF804A, on white matter microstructure in health, schizophrenia and bipolar disorder1.From Gene to Behavior: L-Type Calcium Channel Mechanisms Underlying Neuropsychiatric Symptoms.Cross-disorder risk gene CACNA1C differentially modulates susceptibility to psychiatric disorders during development and adulthood.The impact of CACNA1C allelic variation on regional gray matter volume in Chinese population.Cacna1c in the Prefrontal Cortex Regulates Depression-Related Behaviors via REDD1.The Planar Cell Polarity Transmembrane Protein Vangl2 Promotes Dendrite, Spine and Glutamatergic Synapse Formation in the Mammalian Forebrain.Genetic Risk Score Analysis in Early-Onset Bipolar Disorder.The Emerging Neurobiology of Bipolar Disorder.Reduced levels of Cacna1c attenuate mesolimbic dopamine system function.CACNA1C SNP rs1006737 associates with bipolar I disorder independent of the Bcl-2 SNP rs956572 variant and its associated effect on intracellular calcium homeostasis.Downregulation of the psychiatric susceptibility gene Cacna1c promotes mitochondrial resilience to oxidative stress in neuronal cells.Psychiatric risk gene Cacna1c determines mitochondrial resilience against oxidative stress in neurons.Cacna1c haploinsufficiency leads to pro-social 50-kHz ultrasonic communication deficits in rats.
P2860
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P2860
A rare mutation of CACNA1C in a patient with bipolar disorder, and decreased gene expression associated with a bipolar-associated common SNP of CACNA1C in brain.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
A rare mutation of CACNA1C in ...... ommon SNP of CACNA1C in brain.
@en
A rare mutation of CACNA1C in ...... ommon SNP of CACNA1C in brain.
@nl
type
label
A rare mutation of CACNA1C in ...... ommon SNP of CACNA1C in brain.
@en
A rare mutation of CACNA1C in ...... ommon SNP of CACNA1C in brain.
@nl
prefLabel
A rare mutation of CACNA1C in ...... ommon SNP of CACNA1C in brain.
@en
A rare mutation of CACNA1C in ...... ommon SNP of CACNA1C in brain.
@nl
P2093
P2860
P356
P1433
P1476
A rare mutation of CACNA1C in ...... ommon SNP of CACNA1C in brain.
@en
P2093
E S Gershon
J A Badner
J Busnello
N Alliey-Rodriguez
P2860
P2888
P304
P356
10.1038/MP.2013.107
P407
P577
2013-08-27T00:00:00Z