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Deletion of mesenchymal glucocorticoid receptor attenuates embryonic lung development and abdominal wall closure.Differential glucocorticoid metabolism in patients with persistent versus resolving inflammatory arthritis.Glucocorticoid-induced osteoporosis - a disorder of mesenchymal stromal cells?DKK1 expression by synovial fibroblasts in very early rheumatoid arthritis associates with lymphocyte adhesion in an in vitro flow co-culture systemSynovial DKK1 expression is regulated by local glucocorticoid metabolism in inflammatory arthritis.Characterisation of fibroblast-like synoviocytes from a murine model of joint inflammation.Local and systemic glucocorticoid metabolism in inflammatory arthritis.11β-Hydroxysteroid dehydrogenase type 1 within muscle protects against the adverse effects of local inflammation.Adrenal gland and bone.The 11beta-hydroxysteroid dehydrogenase enzymes--arbiters of the effects of glucocorticoids in synovium and bone.Targeting 11β-hydroxysteroid dehydrogenases: a novel approach to manipulating local glucocorticoid levels with implications for rheumatic disease.Glucocorticoid metabolism in rheumatoid arthritis.Expression of 11β-hydroxysteroid dehydrogenase enzymes in human osteosarcoma: potential role in pathogenesis and as targets for treatments.Cerebral Oxidative Stress and Microvasculature Defects in TNF-α Expressing Transgenic and Porphyromonas gingivalis-Infected ApoE-/- Mice.Synergistic induction of local glucocorticoid generation by inflammatory cytokines and glucocorticoids: implications for inflammation associated bone loss.Inflammatory regulation of glucocorticoid metabolism in mesenchymal stromal cells.Differential expression, function and response to inflammatory stimuli of 11beta-hydroxysteroid dehydrogenase type 1 in human fibroblasts: a mechanism for tissue-specific regulation of inflammation.TNFα depleting therapy improves fertility and animal welfare in TNFα-driven transgenic models of polyarthritis when administered in their routine breeding.Glucocorticoid activation by 11β-hydroxysteroid dehydrogenase enzymes in relation to inflammation and glycaemic control in chronic kidney disease: a cross-sectional study11 Beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritisGlucocorticoids and Bone: Consequences of Endogenous and Exogenous Excess and Replacement TherapyLocalization, Age- and Site-Dependent Expression, and Regulation of 11β-Hydroxysteroid Dehydrogenase Type 1 in SkinTherapeutic glucocorticoids: mechanisms of actions in rheumatic diseasesUnravelling how glucocorticoids work in rheumatoid arthritisExploring the Interface between Inflammatory and Therapeutic Glucocorticoid Induced Bone and Muscle LossTherapeutic glucocorticoids prevent bone loss but drive muscle wasting when administered in chronic polyarthritis11β-HSD1 plays a critical role in trabecular bone loss associated with systemic glucocorticoid therapy
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Rowan Hardy
@ast
Rowan Hardy
@en
Rowan Hardy
@es
Rowan Hardy
@nl
Rowan Hardy
@sl
type
label
Rowan Hardy
@ast
Rowan Hardy
@en
Rowan Hardy
@es
Rowan Hardy
@nl
Rowan Hardy
@sl
prefLabel
Rowan Hardy
@ast
Rowan Hardy
@en
Rowan Hardy
@es
Rowan Hardy
@nl
Rowan Hardy
@sl
P106
P21
P31
P496
0000-0001-6938-6739