An insertion mutant in DQA1*0501 restores susceptibility to HLA-DM: implications for disease associations.
about
Human leukocyte Antigen-DM polymorphisms in autoimmune diseasesSusceptibility to HLA-DM Protein Is Determined by a Dynamic Conformation of Major Histocompatibility Complex Class II Molecule Bound with PeptideOn the perils of poor editing: regulation of peptide loading by HLA-DQ and H2-A molecules associated with celiac disease and type 1 diabetes.Pulse-chase analysis for studies of MHC class II biosynthesis, maturation, and peptide loading.The nonconventional MHC class II molecule DM governs diabetes susceptibility in NOD miceCell-surface MHC density profiling reveals instability of autoimmunity-associated HLA.The mechanism of HLA-DM induced peptide exchange in the MHC class II antigen presentation pathwayHLA Immune Function Genes in Autism.Endogenous antigen processing drives the primary CD4+ T cell response to influenza.pH-susceptibility of HLA-DO tunes DO/DM ratios to regulate HLA-DM catalytic activity.Functional proteome of macrophage carried nanoformulated antiretroviral therapy demonstrates enhanced particle carrying capacityMechanisms of peptide repertoire selection by HLA-DMMHC Class II Protein Turnover In vivo and Its Relevance for Autoimmunity in Non-Obese Diabetic Mice.Exposing the Specific Roles of the Invariant Chain Isoforms in Shaping the MHC Class II Peptidome.Conformational variation in structures of classical and non-classical MHCII proteins and functional implications.Structural Characteristics of HLA-DQ that May Impact DM Editing and Susceptibility to Type-1 Diabetes.The Repertoires of Peptides Presented by MHC-II in the Thymus and in Peripheral Tissue: A Clue for Autoimmunity?HLA-DM and HLA-DO, key regulators of MHC-II processing and presentation.Measurement of Peptide Binding to MHC Class II Molecules by Fluorescence Polarization.Type 1 diabetes associated HLA-DQ2 and DQ8 molecules are relatively resistant to HLA-DM mediated release of invariant chain-derived CLIP peptidesPeptidomic analysis of type 1 diabetes associated HLA-DQ molecules and the impact of HLA-DM on peptide repertoire editing.The Other Function: Class II-Restricted Antigen Presentation by B Cells.A novel method to measure HLA-DM-susceptibility of peptides bound to MHC class II molecules based on peptide binding competition assay and differential IC(50) determination.A TCRα framework-centered codon shapes a biased T cell repertoire through direct MHC and CDR3β interactions.MHC class II complexes sample intermediate states along the peptide exchange pathway.CD4+ T cell autoimmunity to hypocretin/orexin and cross-reactivity to a 2009 H1N1 influenza A epitope in narcolepsy.Unraveling the structural basis for the unusually rich association of human leukocyte antigen DQ2.5 with class-II-associated invariant chain peptides.
P2860
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P2860
An insertion mutant in DQA1*0501 restores susceptibility to HLA-DM: implications for disease associations.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
An insertion mutant in DQA1*05 ...... ions for disease associations.
@en
An insertion mutant in DQA1*05 ...... ions for disease associations.
@nl
type
label
An insertion mutant in DQA1*05 ...... ions for disease associations.
@en
An insertion mutant in DQA1*05 ...... ions for disease associations.
@nl
prefLabel
An insertion mutant in DQA1*05 ...... ions for disease associations.
@en
An insertion mutant in DQA1*05 ...... ions for disease associations.
@nl
P2093
P2860
P356
P1476
An insertion mutant in DQA1*05 ...... tions for disease associations
@en
P2093
Elizabeth D Mellins
Henriette Macmillan
John Sidney
Michael Strohman
Taejin Yoon
Tieying Hou
Zhenjun Chen
P2860
P304
P356
10.4049/JIMMUNOL.1100255
P407
P577
2011-07-20T00:00:00Z