about
Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stressGenetic variation in responses to dietary restriction--an unbiased tool for hypothesis testingRelationship between mitochondrial electron transport chain dysfunction, development, and life extension in Caenorhabditis elegansdaf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegansQuantitative trait loci affecting survival and fertility-related traits in Caenorhabditis elegans show genotype-environment interactions, pleiotropy and epistasisA stress-responsive glutathione S-transferase confers resistance to oxidative stress in Caenorhabditis elegans.Transmission of mutant phenotypes from ES cells to adult mice.Life-span extension by dietary restriction is mediated by NLP-7 signaling and coelomocyte endocytosis in C. elegans.Absence of strong heterosis for life span and other life history traits in Caenorhabditis elegansGerontogenes mediate health and longevity in nematodes through increasing resistance to environmental toxins and stressors.Genetic dissection of dietary restriction in mice supports the metabolic efficiency model of life extension.The metabotropic glutamate receptor subtype 5 mediates sensitivity to the sedative properties of ethanol.Ethanol teratogenesis in five inbred strains of mice.Long-lived mitochondrial (Mit) mutants of Caenorhabditis elegans utilize a novel metabolismSubtle decreases in DNA methylation and gene expression at the mouse Igf2 locus following prenatal alcohol exposure: effects of a methyl-supplemented diet.Relationship between increased longevity and stress resistance as assessed through gerontogene mutations in Caenorhabditis elegans.Caenorhabditis elegans 2007: the premier model for the study of aging.Aging can be genetically dissected into component processes using long-lived lines of Caenorhabditis elegans.A stress-sensitive reporter predicts longevity in isogenic populations of Caenorhabditis elegans.Increased frequency of deletions in the mitochondrial genome with age of Caenorhabditis elegans.Longevity genes in the nematode Caenorhabditis elegans also mediate increased resistance to stress and prevent disease.Detection of deletions in the mitochondrial genome of Caenorhabditis elegans.Caenorhabditis elegans DNA does not contain 5-methylcytosine at any time during development or aging.The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specificGenetic dissection of late-life fertility in Caenorhabditis elegans.Subfield history: Caenorhabditis elegans as a system for analysis of the genetics of aging.The nature and identification of quantitative trait loci: a community's view.Advantages and disadvantages of Caenorhabditis elegans for aging research.Lower body temperature as a potential mechanism of life extension in homeotherms.Expression of a single-copy hsp-16.2 reporter predicts life spanGene expression changes in C57BL/6J and DBA/2J mice following prenatal alcohol exposure.Fertility/longevity trade-offs under limiting-male conditions in mating populations of Caenorhabditis elegansDietary restriction in the nematode Caenorhabditis elegans.Quantitative trait loci controlling halothane sensitivity in Caenorhabditis elegansGenetic analysis of life-span in Caenorhabditis elegansGenetic variation in the murine lifespan response to dietary restriction: from life extension to life shortening.The quest for genetic determinants of human longevity: challenges and insights.Genetic analysis of hyl-1, the C. elegans homolog of LAG1/LASS1.Hormesis and aging in Caenorhabditis elegans.Recent results: biomarkers of aging.
P50
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P50
description
Forscher
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hulumtues
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researcher
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wetenschapper
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հետազոտող
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name
Thomas Johnson
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Thomas Johnson
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Thomas Johnson
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Thomas Johnson
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Thomas Johnson
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Томас Джонсон
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توماس جونسون
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type
label
Thomas Johnson
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Thomas Johnson
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Thomas Johnson
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Thomas Johnson
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Thomas Johnson
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Томас Джонсон
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توماس جونسون
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prefLabel
Thomas Johnson
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Thomas Johnson
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Thomas Johnson
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Thomas Johnson
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Thomas Johnson
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Томас Джонсон
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توماس جونسون
@ar
P106
P21
P31
P496
0000-0001-7147-8237