about
"Soluble Tissue Factor" in the 21st Century: Definitions, Biochemistry, and Pathophysiological Role in Thrombus FormationProstanoids and prostanoid receptors in signal transductionThe pleiotropic effects of tissue factor: a possible role for factor VIIa-induced intracellular signalling?The v-Crk oncogene enhances cell survival and induces activation of protein kinase B/Akt.Hematopoietic microRNA-126 protects against renal ischemia/reperfusion injury by promoting vascular integrity.Tissue Factor promotes breast cancer stem cell activity in vitro.Cell biology of tissue factor, an unusual member of the cytokine receptor family.Cooperation of tissue factor cytoplasmic domain and PAR2 signaling in breast cancer development.Protease-activated receptor (PAR)2, but not PAR1, is involved in collateral formation and anti-inflammatory monocyte polarization in a mouse hind limb ischemia model.Disulfide isomerization switches tissue factor from coagulation to cell signalingTissue factor signal transduction in angiogenesis.Orthotopic injection of breast cancer cells into the mammary fat pad of mice to study tumor growth.Tissue factor-dependent chemokine production aggravates experimental colitis.Tissue factor as an evolutionary conserved cytokine receptor: Implications for inflammation and signal transduction.Splice variants of tissue factor promote monocyte-endothelial interactions by triggering the expression of cell adhesion molecules via integrin-mediated signaling.Tissue factor and cancer metastasis: the role of intracellular and extracellular signaling pathwaysAssociation between micro particle-tissue factor activity, factor VIII activity and recurrent VTE in patients with acute pulmonary embolism.Alternatively spliced tissue factor synergizes with the estrogen receptor pathway in promoting breast cancer progression.Inhibition of tissue factor signaling suppresses tumor growthEmerging insights in tissue factor-dependent signaling events.Validity of bioluminescence measurements for noninvasive in vivo imaging of tumor load in small animals.Alternatively spliced tissue factor promotes breast cancer growth in a β1 integrin-dependent manner.Antibody-based targeting of alternatively spliced tissue factor: a new approach to impede the primary growth and spread of pancreatic ductal adenocarcinoma.Alternatively spliced tissue factor induces angiogenesis through integrin ligation.Tissue factor signaling: a multi-faceted function in biological processes.Thiol pathways in the regulation of tissue factor prothrombotic activity.Tissue factor isoforms in cancer and coagulation: may the best isoform win.Effects of tumor-expressed coagulation factors on cancer progression and venous thrombosis: is there a key factor?d-Asb11 is an essential mediator of canonical Delta-Notch signalling.Tissue Factor: Old and New Links with Cancer Biology.Interplay between alternatively spliced Tissue Factor and full length Tissue Factor in modulating coagulant activity of endothelial cells.Reciprocal links between venous thromboembolism, coagulation factors and ovarian cancer progression.Anticoagulants versus cancer.Alternatively spliced tissue factor contributes to tumor spread and activation of coagulation in pancreatic ductal adenocarcinoma.Murine tissue factor coagulant activity is critically dependent on the presence of an intact allosteric disulfide.Coagulation factor Xa drives tumor cells into apoptosis through BH3-only protein Bim up-regulation.FVIIa:TF induces cell survival via G12/G13-dependent Jak/STAT activation and BclXL production.Coagulation factors VIIa and Xa inhibit apoptosis and anoikis.Activation of the canonical beta-catenin pathway by histamine.VIIa/tissue factor interaction results in a tissue factor cytoplasmic domain-independent activation of protein synthesis, p70, and p90 S6 kinase phosphorylation.
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P50
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Henri H Versteeg
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Henri H Versteeg
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Henri H Versteeg
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Henri H Versteeg
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Henri H Versteeg
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Henri H Versteeg
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Henri H Versteeg
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Henri H Versteeg
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Henri H Versteeg
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Henri H Versteeg
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Henri H Versteeg
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Henri H Versteeg
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Henri H Versteeg
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P1053
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P2038
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