Persistent malignant stem cells in del(5q) myelodysplasia in remission.
about
Salinomycin as a drug for targeting human cancer stem cellsShort- and long-term benefits of lenalidomide treatment in patients with lower-risk del(5q) myelodysplastic syndromesMetastatic cancer stem cells: from the concept to therapeuticsDeconstructing innate immune signaling in myelodysplastic syndromesCancer stem cells: relevance to clinical transplantationEpigenetic regulation of hematopoietic stem cell agingPP2A: The Achilles Heal in MDS with 5q DeletionIn vitro models of cancer stem cells and clinical applicationsApplication of single-cell genomics in cancer: promise and challengesEstablished and emerging targeted therapies in the myelodysplastic syndromes.Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivoThe clinical safety of lenalidomide in multiple myeloma and myelodysplastic syndromes.Lenalidomide: a review of its use in patients with transfusion-dependent anaemia due to low- or intermediate-1-risk myelodysplastic syndrome associated with 5q chromosome deletion.A pilot phase I dose finding safety study of the thrombopoietin-receptor agonist, eltrombopag, in patients with myelodysplastic syndrome treated with azacitidine.Efficacy and Safety of Lenalidomide for Treatment of Low-/Intermediate-1-Risk Myelodysplastic Syndromes with or without 5q Deletion: A Systematic Review and Meta-AnalysisLenalidomide combined with intensive chemotherapy in acute myeloid leukemia and higher-risk myelodysplastic syndrome with 5q deletion. Results of a phase II study by the Groupe Francophone Des Myélodysplasies.Long-Term Response in a Patient with del(5q) Myelodysplastic Syndrome Who Discontinued Lenalidomide and Obtained a Good Response and Tolerance to Rechallenge.Quiescent hematopoietic stem cells accumulate DNA damage during aging that is repaired upon entry into cell cycleA critical review of the molecular pathophysiology of lenalidomide sensitivity in 5q - myelodysplastic syndromes.Combination of azacitidine and lenalidomide in myelodysplastic syndromes or acute myeloid leukemia-a wise liaison?Concise review: preleukemic stem cells: molecular biology and clinical implications of the precursors to leukemia stem cellsGenomic alterations in abnormal neutrophils isolated from adult patients with systemic lupus erythematosusClinical utility of lenalidomide in the treatment of myelodysplastic syndromesProteomic profiling identifies distinct protein patterns in acute myelogenous leukemia CD34+CD38- stem-like cells.Feedback signals in myelodysplastic syndromes: increased self-renewal of the malignant clone suppresses normal hematopoiesis.Dexamethasone and lenalidomide have distinct functional effects on erythropoiesis.Persistence of leukemia stem cells in chronic myelogenous leukemia patients in prolonged remission with imatinib treatmentPhotochemical internalisation, a minimally invasive strategy for light-controlled endosomal escape of cancer stem cell-targeting therapeutics.A clinically relevant population of leukemic CD34(+)CD38(-) cells in acute myeloid leukemiaSecond malignancies after multiple myeloma: from 1960s to 2010s.Phase 2 study of rituximab-ABVD in classical Hodgkin lymphoma.Alkylator-Induced and Patient-Derived Xenograft Mouse Models of Therapy-Related Myeloid Neoplasms Model Clinical Disease and Suggest the Presence of Multiple Cell Subpopulations with Leukemia Stem Cell ActivityThe evolving concept of cancer and metastasis stem cellsHeterogeneity of Cancer Stem Cells: Rationale for Targeting the Stem Cell Niche.Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterationsAutophagy limits proliferation and glycolytic metabolism in acute myeloid leukemiaConcise review: Cancer stem cells and minimal residual diseaseImportant genes in the pathogenesis of 5q- syndrome and their connection with ribosomal stress and the innate immune system pathway.Molecular pathophysiology of myelodysplastic syndromes.Preclinical activity of the novel B-cell-specific Moloney murine leukemia virus integration site 1 inhibitor PTC-209 in acute myeloid leukemia: Implications for leukemia therapy
P2860
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P2860
Persistent malignant stem cells in del(5q) myelodysplasia in remission.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Persistent malignant stem cells in del
@nl
Persistent malignant stem cells in del(5q) myelodysplasia in remission.
@en
type
label
Persistent malignant stem cells in del
@nl
Persistent malignant stem cells in del(5q) myelodysplasia in remission.
@en
prefLabel
Persistent malignant stem cells in del
@nl
Persistent malignant stem cells in del(5q) myelodysplasia in remission.
@en
P2093
P50
P356
P1476
Persistent malignant stem cells in del(5q) myelodysplasia in remission.
@en
P2093
Andrea Horvat
Bertil Johansson
Bodil Strömbeck
Brigitte Schlegelberger
Eva Hellström-Lindberg
Gudrun Göhring
Helen Ferry
Ingbritt Astrand-Grundström
Kristina Anderson
Lars Nilsson
P304
P356
10.1056/NEJMOA0912228
P407
P577
2010-09-01T00:00:00Z