Systemic blockade of P2X3 and P2X2/3 receptors attenuates bone cancer pain behaviour in rats. - Wikidata - wikimedia - TriplyDB

Systemic blockade of P2X3 and P2X2/3 receptors attenuates bone cancer pain behaviour in rats.

Systemic blockade of P2X3 and P2X2/3 receptors attenuates bone cancer pain behaviour in rats.

http://www.wikidata.org/entity/Q42923060

about

The role of purinergic receptors in cancer-induced bone pain Molecular and functional properties of P2X receptors--recent progress and persisting challenges Purinergic signalling and cancer The Physiology of Bone Pain. How Much Do We Really Know?Use of Animal Models in Understanding Cancer-induced Bone Pain In pursuit of P2X3 antagonists: novel therapeutics for chronic pain and afferent sensitization.Urothelial signaling.Dissociation between the relief of skeletal pain behaviors and skin hypersensitivity in a model of bone cancer pain.Optimization and In Vivo Profiling of a Refined Rat Model of Walker 256 Breast Cancer Cell-Induced Bone Pain Using Behavioral, Radiological, Histological, Immunohistochemical and Pharmacological Methods The neurobiology of cancer pain.Adenosine triphosphate drives head and neck cancer pain through P2X2/3 heterotrimers.P2X receptors: New players in cancer pain.Anatomical and physiological factors contributing to chronic muscle pain Sensitization of P2X3 receptors by cystathionine β-synthetase mediates persistent pain hypersensitivity in a rat model of lumbar disc herniation.Prenatal expression of purinergic receptor P2X3 in human dorsal root ganglion Behavioral and neurochemical analysis of ongoing bone cancer pain in rats.Enhanced binding capability of nuclear factor-κB with demethylated P2X3 receptor gene contributes to cancer pain in rats.Enhancement of purinergic signalling by excessive endogenous ATP in resiniferatoxin (RTX) neuropathy.Painful boney metastases.A Method to Target and Isolate Airway-innervating Sensory Neurons in Mice Modulation of P2X3 and P2X2/3 Receptors by Monoclonal Antibodies Rho/ROCK acts downstream of lysophosphatidic acid receptor 1 in modulating P2X3 receptor-mediated bone cancer pain in rats.The non-selective cannabinoid receptor agonist WIN 55,212-2 attenuates responses of C-fiber nociceptors in a murine model of cancer pain Purinergic signalling in the musculoskeletal system.Overexpression of suppressor of cytokine signaling 3 in dorsal root ganglion attenuates cancer-induced pain in rats.Protons and Ca2+: ionic allies in tumor progression?Desensitization properties of P2X3 receptors shaping pain signaling.New insights of nociceptor sensitization in bone cancer pain.Emerging factors in the progression of cancer-related pain.The scaffold protein calcium/calmodulin-dependent serine protein kinase controls ATP release in sensory ganglia upon P2X3 receptor activation and is part of an ATP keeper complex.Targeting glia for bone cancer pain.Synergistic combinations of the dual enkephalinase inhibitor PL265 given orally with various analgesic compounds acting on different targets, in a murine model of cancer-induced bone pain.Mediation of Movement-Induced Breakthrough Cancer Pain by IB4-Binding Nociceptors in Rats.Up-regulation of brain-derived neurotrophic factor in the dorsal root ganglion of the rat bone cancer pain model.P2X3 antagonists: novel therapeutics for afferent sensitization and chronic pain.Characterization of three diaminopyrimidines as potent and selective antagonists of P2X3 and P2X2/3 receptors with in vivo efficacy in a pain model.Postsynaptic P2X3-containing receptors in gustatory nerve fibres mediate responses to all taste qualities in mice.Purinergic Signalling: Therapeutic Developments.Cancer pain physiology.Spontaneous firing and evoked responses of spinal nociceptive neurons are attenuated by blockade of P2X3 and P2X2/3 receptors in inflamed rats.

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P2860

Systemic blockade of P2X3 and P2X2/3 receptors attenuates bone cancer pain behaviour in rats.

http://www.wikidata.org/entity/Q42923060

description

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name

Systemic blockade of P2X3 and ...... cancer pain behaviour in rats.

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Systemic blockade of P2X3 and ...... cancer pain behaviour in rats.

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Systemic blockade of P2X3 and ...... cancer pain behaviour in rats.

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Systemic blockade of P2X3 and ...... cancer pain behaviour in rats.

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Systemic blockade of P2X3 and ...... cancer pain behaviour in rats.

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Systemic blockade of P2X3 and ...... cancer pain behaviour in rats.

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Systemic blockade of P2X3 and ...... cancer pain behaviour in rats.

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Anthony H Dickenson

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Anthony P D W Ford

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Debra A Cockayne

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Fabien Marchand

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Meirion Davies

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Philip A Nunn

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Ping K Yip

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Sital Patel

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Timothy K Y Kaan

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Yu Zhong

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P2860

P2X7-dependent release of interleukin-1beta and nociception in the spinal cord following lipopolysaccharide

Pharmacology of P2X channels

Warm-coding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors

Effects of the RANKL inhibitor, osteoprotegerin, on the pain and histopathology of bone cancer in rats

P2X2 knockout mice and P2X2/P2X3 double knockout mice reveal a role for the P2X2 receptor subunit in mediating multiple sensory effects of ATP

Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice

Metastasis to bone: causes, consequences and therapeutic opportunities

MAP kinase and pain.

Disease modifying and anti-nociceptive effects of the bisphosphonate, zoledronic acid in a model of bone cancer pain.

A phenotypically restricted set of primary afferent nerve fibers innervate the bone versus skin: therapeutic opportunity for treating skeletal pain.

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10.1093/BRAIN/AWQ194

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9

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133

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Marzia Malcangio

Stephen B McMahon

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2010-09-01T00:00:00Z

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