Ceramide biogenesis is required for radiation-induced apoptosis in the germ line of C. elegans.
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In vivo delivery of FTY720 prevents radiation-induced ovarian failure and infertility in adult female nonhuman primatesA critical role for ceramide synthase 2 in liver homeostasis: II. insights into molecular changes leading to hepatopathySphingolipid signaling in metabolic disordersFunctional loss of two ceramide synthases elicits autophagy-dependent lifespan extension in C. elegansASM-3 acid sphingomyelinase functions as a positive regulator of the DAF-2/AGE-1 signaling pathway and serves as a novel anti-aging targetRibosome synthesis and MAPK activity modulate ionizing radiation-induced germ cell apoptosis in Caenorhabditis elegansThe targeting of plasmalemmal ceramide to mitochondria during apoptosisThe Caenorhabditis elegans homolog of Gen1/Yen1 resolvases links DNA damage signaling to DNA double-strand break repairIdentification and characterization of murine mitochondria-associated neutral sphingomyelinase (MA-nSMase), the mammalian sphingomyelin phosphodiesterase 5Phylogeny and function of the invertebrate p53 superfamilyGenetic loci associated with circulating levels of very long-chain saturated fatty acids.Tumor radiation response enhancement by acoustical stimulation of the vasculature.Evidence that CED-9/Bcl2 and CED-4/Apaf-1 localization is not consistent with the current model for C. elegans apoptosis induction.Glucose or Altered Ceramide Biosynthesis Mediate Oxygen Deprivation Sensitivity Through Novel Pathways Revealed by Transcriptome Analysis in Caenorhabditis elegans.Antiapoptotic roles of ceramide-synthase-6-generated C16-ceramide via selective regulation of the ATF6/CHOP arm of ER-stress-response pathways.Tumor control outcomes after hypofractionated and single-dose stereotactic image-guided intensity-modulated radiotherapy for extracranial metastases from renal cell carcinoma.Ceramide synthesis regulates T cell activity and GVHD development.Novel Mutations in Synaptic Transmission Genes Suppress Neuronal Hyperexcitation in Caenorhabditis elegans.Caenorhabditis elegans pathways that surveil and defend mitochondria.Mitochondrial ceramide-rich macrodomains functionalize Bax upon irradiation.Inhibition of ceramide biosynthesis preserves photoreceptor structure and function in a mouse model of retinitis pigmentosa.Membranes in balance: mechanisms of sphingolipid homeostasis.Hydrophobic analogues of rhodamine B and rhodamine 101: potent fluorescent probes of mitochondria in living C. elegans.Developmentally regulated ceramide synthase 6 increases mitochondrial Ca2+ loading capacity and promotes apoptosis.Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans.Oxidized phospholipids induce ceramide accumulation in RAW 264.7 macrophages: role of ceramide synthases.Ceramide synthase-dependent ceramide generation and programmed cell death: involvement of salvage pathway in regulating postmitochondrial events.Distribution and functions of sterols and sphingolipids.C. elegans CEP-1/p53 and BEC-1 are involved in DNA repair.Novel pathway of ceramide production in mitochondria: thioesterase and neutral ceramidase produce ceramide from sphingosine and acyl-CoA.Many ceramides.Results of a phase II trial of gemcitabine plus doxorubicin in patients with recurrent head and neck cancers: serum C₁₈-ceramide as a novel biomarker for monitoring response.Role of sphingolipids in murine radiation-induced lung injury: protection by sphingosine 1-phosphate analogs.Regulation of ceramide synthase-mediated crypt epithelium apoptosis by DNA damage repair enzymesCeramide-rich platforms in transmembrane signaling.Recruitment of sphingosine kinase to presynaptic terminals by a conserved muscarinic signaling pathway promotes neurotransmitter releaseCommunication between host organism and cancer cells is transduced by systemic sphingosine kinase 1/sphingosine 1-phosphate signalling to regulate tumour metastasis.Sphingolipid metabolism cooperates with BAK and BAX to promote the mitochondrial pathway of apoptosisSIRT3 Deacetylates Ceramide Synthases: IMPLICATIONS FOR MITOCHONDRIAL DYSFUNCTION AND BRAIN INJURY.Localized sphingolipid signaling at presynaptic terminals is regulated by calcium influx and promotes recruitment of priming factors.
P2860
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P2860
Ceramide biogenesis is required for radiation-induced apoptosis in the germ line of C. elegans.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Ceramide biogenesis is require ...... n the germ line of C. elegans.
@en
Ceramide biogenesis is require ...... n the germ line of C. elegans.
@nl
type
label
Ceramide biogenesis is require ...... n the germ line of C. elegans.
@en
Ceramide biogenesis is require ...... n the germ line of C. elegans.
@nl
prefLabel
Ceramide biogenesis is require ...... n the germ line of C. elegans.
@en
Ceramide biogenesis is require ...... n the germ line of C. elegans.
@nl
P2093
P2860
P356
P1433
P1476
Ceramide biogenesis is require ...... n the germ line of C. elegans.
@en
P2093
Carine W Maurer
Diane D Lu
Richard Allan
Richard Kolesnick
Shai Shaham
Xianglei Yin
Xinzhu Deng
P2860
P304
P356
10.1126/SCIENCE.1158111
P407
P577
2008-10-01T00:00:00Z