Ceramide biogenesis is required for radiation-induced apoptosis in the germ line of C. elegans. - Wikidata - wikimedia - TriplyDB

Ceramide biogenesis is required for radiation-induced apoptosis in the germ line of C. elegans.

Ceramide biogenesis is required for radiation-induced apoptosis in the germ line of C. elegans.

http://www.wikidata.org/entity/Q42936816

about

In vivo delivery of FTY720 prevents radiation-induced ovarian failure and infertility in adult female nonhuman primates A critical role for ceramide synthase 2 in liver homeostasis: II. insights into molecular changes leading to hepatopathy Sphingolipid signaling in metabolic disorders Functional loss of two ceramide synthases elicits autophagy-dependent lifespan extension in C. elegans ASM-3 acid sphingomyelinase functions as a positive regulator of the DAF-2/AGE-1 signaling pathway and serves as a novel anti-aging target Ribosome synthesis and MAPK activity modulate ionizing radiation-induced germ cell apoptosis in Caenorhabditis elegans The targeting of plasmalemmal ceramide to mitochondria during apoptosis The Caenorhabditis elegans homolog of Gen1/Yen1 resolvases links DNA damage signaling to DNA double-strand break repair Identification and characterization of murine mitochondria-associated neutral sphingomyelinase (MA-nSMase), the mammalian sphingomyelin phosphodiesterase 5 Phylogeny and function of the invertebrate p53 superfamily Genetic loci associated with circulating levels of very long-chain saturated fatty acids.Tumor radiation response enhancement by acoustical stimulation of the vasculature.Evidence that CED-9/Bcl2 and CED-4/Apaf-1 localization is not consistent with the current model for C. elegans apoptosis induction.Glucose or Altered Ceramide Biosynthesis Mediate Oxygen Deprivation Sensitivity Through Novel Pathways Revealed by Transcriptome Analysis in Caenorhabditis elegans.Antiapoptotic roles of ceramide-synthase-6-generated C16-ceramide via selective regulation of the ATF6/CHOP arm of ER-stress-response pathways.Tumor control outcomes after hypofractionated and single-dose stereotactic image-guided intensity-modulated radiotherapy for extracranial metastases from renal cell carcinoma.Ceramide synthesis regulates T cell activity and GVHD development.Novel Mutations in Synaptic Transmission Genes Suppress Neuronal Hyperexcitation in Caenorhabditis elegans.Caenorhabditis elegans pathways that surveil and defend mitochondria.Mitochondrial ceramide-rich macrodomains functionalize Bax upon irradiation.Inhibition of ceramide biosynthesis preserves photoreceptor structure and function in a mouse model of retinitis pigmentosa.Membranes in balance: mechanisms of sphingolipid homeostasis.Hydrophobic analogues of rhodamine B and rhodamine 101: potent fluorescent probes of mitochondria in living C. elegans.Developmentally regulated ceramide synthase 6 increases mitochondrial Ca2+ loading capacity and promotes apoptosis.Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans.Oxidized phospholipids induce ceramide accumulation in RAW 264.7 macrophages: role of ceramide synthases.Ceramide synthase-dependent ceramide generation and programmed cell death: involvement of salvage pathway in regulating postmitochondrial events.Distribution and functions of sterols and sphingolipids.C. elegans CEP-1/p53 and BEC-1 are involved in DNA repair.Novel pathway of ceramide production in mitochondria: thioesterase and neutral ceramidase produce ceramide from sphingosine and acyl-CoA.Many ceramides.Results of a phase II trial of gemcitabine plus doxorubicin in patients with recurrent head and neck cancers: serum C₁₈-ceramide as a novel biomarker for monitoring response.Role of sphingolipids in murine radiation-induced lung injury: protection by sphingosine 1-phosphate analogs.Regulation of ceramide synthase-mediated crypt epithelium apoptosis by DNA damage repair enzymes Ceramide-rich platforms in transmembrane signaling.Recruitment of sphingosine kinase to presynaptic terminals by a conserved muscarinic signaling pathway promotes neurotransmitter release Communication between host organism and cancer cells is transduced by systemic sphingosine kinase 1/sphingosine 1-phosphate signalling to regulate tumour metastasis.Sphingolipid metabolism cooperates with BAK and BAX to promote the mitochondrial pathway of apoptosis SIRT3 Deacetylates Ceramide Synthases: IMPLICATIONS FOR MITOCHONDRIAL DYSFUNCTION AND BRAIN INJURY.Localized sphingolipid signaling at presynaptic terminals is regulated by calcium influx and promotes recruitment of priming factors.

P2860

Q24632632-6B75AD5A-E6B8-4192-9B65-60342527600B Q24634622-DE9748E0-F23B-4D8E-87A1-C93BFF43AD2C Q26992148-ED3AF072-8B92-4CE7-8522-125729BFB80D Q27310570-E9DACA75-D923-464B-B22D-EE77A35C4E48 Q27317086-F2C69BD6-F448-4571-A883-901C629EFDEC Q27319572-B2A5CEEC-7701-4A4C-98E2-54904D17438E Q27323504-45857D8D-6503-48B3-BC5D-2F9FFAC4780E Q28474884-58390E1D-0E76-4CD1-A60D-4E27D659EEDB Q28590499-72432D3F-878E-4D73-9AF0-2AB4E16D71F8 Q28751278-5EB889A8-D894-4180-8CB4-57A0ED9E9B1C Q30301364-9D905890-A7A2-4CF9-A79A-F5B362F6C61A Q30458925-7440762B-C7E1-4FB0-9554-54FBF2CF4466 Q30505349-5A4D8113-3923-4AE6-A8C1-08F35A4B4210 Q30823934-0D438EC7-BA11-4F8C-B8A5-0FB479892D76 Q33552843-FBD3DC70-414F-4420-8995-46223E4BAFE7 Q33668241-0E94EB2F-220B-44C4-81C9-FCDBDB928F42 Q33703218-338AB3F2-497B-4C4C-B4EF-542D5BE16C8D Q33877282-90C446A6-70F2-430C-BB66-BA6BAB594EAF Q33915292-BED92DB3-DA79-4E29-AA1D-02BC500DD275 Q33939529-6927C394-9531-445E-99D2-432149847B34 Q34276549-5B2A7C9E-BE10-4EF1-B256-19FFFD511528 Q34330398-8E6EC45F-B3CC-4291-8B27-BD2EED01337E Q34568175-0ADC46DE-E4BF-4211-B0E2-CD35C090C032 Q34575828-638AAE04-2F31-4E29-B4CB-5A993EDA08C5 Q34621750-962ABA94-E341-4E1D-A6C9-D4CB8A15DEF8 Q34921734-4BA2215A-0FBE-4834-8A2D-E91D41BD8282 Q34963246-7DC6FC3E-6F39-4DFB-870C-70D625324D9E Q35006514-620A7B57-92AB-4B49-B074-4E1B21A66223 Q35106336-55245DB5-E05C-4D3B-9CEC-A368EE60866D Q35107592-035DA112-834C-452D-BD5D-CD8593E87077 Q35149996-8918585D-6B04-49B0-9E75-9B1F57671AAC Q35223807-265D5EA7-71E0-4A21-95E4-CD7DAFB7FC5E Q35225101-07133C7F-D911-4909-B0EE-70E839AE2DA3 Q35633868-90483868-EF3D-4B79-92F1-899B4E8AD20A Q35633883-B2EF51E0-4FC0-48AB-88D4-2FF768383037 Q35988918-56ECB770-9FE0-451E-838C-A11049B98DEB Q36386459-55CFDC3A-005C-47B1-B249-55A5D30AEFB3 Q36422392-11ECBF12-51F1-4B3E-A535-0BDA403FEDE9 Q36489335-F6CC5C91-E3C5-4A62-AA32-3D225065F27E Q36534308-069BDB33-67D2-4CFB-97C7-6D83B9AB1E31

P2860

Ceramide biogenesis is required for radiation-induced apoptosis in the germ line of C. elegans.

http://www.wikidata.org/entity/Q42936816

description

2008 nî lūn-bûn

@nan

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

2008年论文

@zh

2008年论文

@zh-cn

name

Ceramide biogenesis is require ...... n the germ line of C. elegans.

@en

Ceramide biogenesis is require ...... n the germ line of C. elegans.

@nl

type

label

Ceramide biogenesis is require ...... n the germ line of C. elegans.

@en

Ceramide biogenesis is require ...... n the germ line of C. elegans.

@nl

prefLabel

Ceramide biogenesis is require ...... n the germ line of C. elegans.

@en

Ceramide biogenesis is require ...... n the germ line of C. elegans.

@nl

P1433

Q42936816-EE9FD2AC-C016-409A-A95E-9980AE646BB1

P1476

Q42936816-EE12F074-06E9-41E5-A35E-CB6B4DAC94DC

P2093

Q42936816-0D7C1D2F-C5A2-425B-BC8F-B8948FECEAD7

Q42936816-0E18CE88-734B-4E71-B9CD-B808978082E0

Q42936816-103147D3-D2A6-4E4C-A619-83898276EDF8

Q42936816-23B21D45-F5F5-4CAA-8445-55FC0E71BDBD

Q42936816-704A75DD-E463-42C4-A08C-79CE375362AA

Q42936816-80AB4AE6-10D9-4366-8A69-C5992BE2680D

Q42936816-87D0A07B-EE30-4F99-BF84-56F5E89AAFE9

Q42936816-BEC48138-E529-4EAD-BE2B-3171FBA98B72

P2860

Q42936816-0AD0CED1-7CBB-4619-992D-0CAFF6997A81

Q42936816-149E89BE-BE4D-42F7-A86A-5097A2C6DA18

Q42936816-3463DA68-3AC0-458F-8B72-24225594AB2E

Q42936816-3BC42C45-D129-40DD-BE7A-D41DB90C302B

Q42936816-40868C02-BDB7-4099-858E-CB2F1BCA0B73

Q42936816-4DDA63BE-3FEA-425C-BBFF-B64399308E21

Q42936816-50994D08-4B82-4A0B-8F02-F1C71CFA934D

Q42936816-55E96E44-F8D7-46DD-9337-5B7BB319EBBA

Q42936816-5E921190-814D-48F9-AF25-5C56613F247E

Q42936816-639CF2BF-4569-4ACA-B726-CC01A219BD27

P304

Q42936816-17456224-C207-484B-8EBF-9FE7F4F512E0

P31

Q42936816-E18AF0D6-E475-482D-AB56-D3761891CE4B

P356

Q42936816-7A4982EB-71D7-46FB-A690-4AE2FFEC8326

P407

Q42936816-A679CCAB-2FC5-49D8-A2F1-D69C4867DB01

P433

Q42936816-63FADBE8-7B0C-4EF9-B882-98A134917D96

P478

Q42936816-B0B52FC4-A634-4454-A60A-A8B75C5DC775

P50

Q42936816-C74A1165-E6F3-42B0-A3C7-3D40063D2ECE

P577

Q42936816-03621C53-D5AB-465F-8916-8395C38BFCD5

P5875

Q42936816-1EA5D239-C578-4883-BC95-72F937A0A8C4

P698

Q42936816-BC88F07D-5CFC-4391-B43C-CA14D334AC56

P921

Q42936816-89000AFF-4B5D-4608-9BE6-2E41045B284E

P932

Q42936816-6112E312-7EE3-4768-A5A5-713456856080

P356

SCIENCE.1158111

P1433

P1476

Ceramide biogenesis is require ...... n the germ line of C. elegans.

@en

P2093

Carine W Maurer

http://www.w3.org/2001/XMLSchema#string

Diane D Lu

http://www.w3.org/2001/XMLSchema#string

Richard Allan

http://www.w3.org/2001/XMLSchema#string

Richard Kolesnick

http://www.w3.org/2001/XMLSchema#string

Shai Shaham

http://www.w3.org/2001/XMLSchema#string

Xianglei Yin

http://www.w3.org/2001/XMLSchema#string

Xinzhu Deng

http://www.w3.org/2001/XMLSchema#string

Zvi Fuks

http://www.w3.org/2001/XMLSchema#string

P2860

Necessary role for the Lag1p motif in (dihydro)ceramide synthase activity

The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9

C. elegans ced-13 can promote apoptosis and is induced in response to DNA damage

C. elegans dynamin-related protein DRP-1 controls severing of the mitochondrial outer membrane

When do Lasses (longevity assurance genes) become CerS (ceramide synthases)?: Insights into the regulation of ceramide synthesis.

Physiological and pathophysiological aspects of ceramide.

Biophysics of sphingolipids I. Membrane properties of sphingosine, ceramides and other simple sphingolipids.

Nonapoptotic role for Apaf-1 in the DNA damage checkpoint.

Loss of sphingosine kinase-1 activates the intrinsic pathway of programmed cell death: modulation of sphingolipid levels and the induction of apoptosis.

Caenorhabditis elegans ABL-1 antagonizes p53-mediated germline apoptosis after ionizing irradiation.

P304

110-115

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1126/SCIENCE.1158111

http://www.w3.org/2001/XMLSchema#string

P407

P433

5898

http://www.w3.org/2001/XMLSchema#string

P478

322

http://www.w3.org/2001/XMLSchema#string

P50

Adriana Haimovitz-Friedman

P577

2008-10-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

23297214

http://www.w3.org/2001/XMLSchema#string

P698

18832646

http://www.w3.org/2001/XMLSchema#string

P921

Caenorhabditis elegans

P932

2585063

http://www.w3.org/2001/XMLSchema#string