The inhibition of arginase by N(omega)-hydroxy-l-arginine controls the growth of Leishmania inside macrophages.
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Modulation of Innate Immune Mechanisms to Enhance Leishmania Vaccine-Induced Immunity: Role of Coinhibitory MoleculesCrystal structure of arginase from Leishmania mexicana and implications for the inhibition of polyamine biosynthesis in parasitic infectionsGrowth factor and Th2 cytokine signaling pathways converge at STAT6 to promote arginase expression in progressive experimental visceral leishmaniasisBone marrow cell derived arginase I is the major source of allergen-induced lung arginase but is not required for airway hyperresponsiveness, remodeling and lung inflammatory responses in mice.Infection with arginase-deficient Leishmania major reveals a parasite number-dependent and cytokine-independent regulation of host cellular arginase activity and disease pathogenesis.Modulation of the arginase pathway in the context of microbial pathogenesis: a metabolic enzyme moonlighting as an immune modulatorCryptococcus neoformans variants generated by phenotypic switching differ in virulence through effects on macrophage activation.Helicobacter pylori arginase inhibits nitric oxide production by eukaryotic cells: a strategy for bacterial survivalAxenic Leishmania amazonensis promastigotes sense both the external and internal arginine pool distinctly regulating the two transporter-coding genes.ArgR-regulated genes are derepressed in the Legionella-containing vacuoleVaccination with plasmid DNA encoding TSA/LmSTI1 leishmanial fusion proteins confers protection against Leishmania major infection in susceptible BALB/c miceProgressive visceral leishmaniasis is driven by dominant parasite-induced STAT6 activation and STAT6-dependent host arginase 1 expression.L-arginine deprivation impairs Leishmania major-specific T-cell responses.Leishmania amazonensis arginase compartmentalization in the glycosome is important for parasite infectivity.Insulin-like growth factor-I induces arginase activity in Leishmania amazonensis amastigote-infected macrophages through a cytokine-independent mechanism.Selective fusion of azurophilic granules with Leishmania-containing phagosomes in human neutrophils.Local increase of arginase activity in lesions of patients with cutaneous leishmaniasis in Ethiopia.Aberrant host defense against Leishmania major in the absence of SLPI.Characterisation of the ex vivo virulence of Leishmania infantum isolates from Phlebotomus perniciosus from an outbreak of human leishmaniosis in Madrid, Spain.Arginase activity in the blood of patients with visceral leishmaniasis and HIV infection.Inhibition profile of Leishmania mexicana arginase reveals differences with human arginase I.Promising therapeutic targets for antileishmanial drugs.Leishmania promotes its own virulence by inducing expression of the host immune inhibitory ligand CD200Toxoplasma polymorphic effectors determine macrophage polarization and intestinal inflammation.The Schistosoma mansoni hepatic egg granuloma provides a favorable microenvironment for sustained growth of Leishmania donovani.The Role of Vitamin D and Vitamin D Receptor in Immunity to Leishmania major InfectionEnhanced replication of Leishmania amazonensis amastigotes in gamma interferon-stimulated murine macrophages: implications for the pathogenesis of cutaneous leishmaniasis.Arginine and polyamines in Helicobacter pylori-induced immune dysregulation and gastric carcinogenesis.L-arginine and cationic amino acid transporter 2B regulate growth and survival of Leishmania amazonensis amastigotes in macrophages.Genetically Modified Live Attenuated Leishmania donovani Parasites Induce Innate Immunity through Classical Activation of Macrophages That Direct the Th1 Response in Mice.Apoptotic mimicry: an altruistic behavior in host/Leishmania interplay.Alternatively activated and immunoregulatory monocytes in human filarial infections.Developments in diagnosis and antileishmanial drugs.Arginase I in myeloid suppressor cells is induced by COX-2 in lung carcinoma.Impact of substrate protonation and tautomerization states on interactions with the active site of arginase I.Competitive metabolism of L-arginine: arginase as a therapeutic target in asthma.Mechanisms of immune evasion in leishmaniasisL-arginine metabolism and its impact on host immunity against Leishmania infectionParasite-derived arginase influences secondary anti-Leishmania immunity by regulating programmed cell death-1-mediated CD4+ T cell exhaustion.Activation of alveolar macrophages via the alternative pathway in herpesvirus-induced lung fibrosis
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P2860
The inhibition of arginase by N(omega)-hydroxy-l-arginine controls the growth of Leishmania inside macrophages.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
The inhibition of arginase by N
@nl
The inhibition of arginase by ...... Leishmania inside macrophages.
@en
type
label
The inhibition of arginase by N
@nl
The inhibition of arginase by ...... Leishmania inside macrophages.
@en
prefLabel
The inhibition of arginase by N
@nl
The inhibition of arginase by ...... Leishmania inside macrophages.
@en
P2093
P2860
P356
P1476
The inhibition of arginase by ...... Leishmania inside macrophages.
@en
P2093
Corraliza I
Gómez-Nieto LC
P2860
P304
P356
10.1084/JEM.193.6.777
P407
P577
2001-03-01T00:00:00Z