Sildenafil treatment in vivo stimulates Leydig cell steroidogenesis via the cAMP/cGMP signaling pathway.
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Molecular Mechanisms Elicited by d-Aspartate in Leydig Cells and SpermatogoniaThe roles of cyclic nucleotide phosphodiesterases (PDEs) in steroidogenesis.Dracaena arborea alleviates ultra-structural spermatogenic alterations in streptozotocin-induced diabetic rats.Testosterone regulates smooth muscle contractile pathways in the rat prostate: emphasis on PDE5 signaling.Defining the phosphodiesterase superfamily members in rat brain microvessels.Tadalafil modulates aromatase activity and androgen receptor expression in a human osteoblastic cell in vitro model.Translational Perspective on the Role of Testosterone in Sexual Function and DysfunctionA sensitive and selective LC-MS/MS analysis coupled with an online sample enrichment technique for H295R steroidogenesis assay and its application in the investigation of the effect of sildenafil on steroidogenesis.Orally applied doxazosin disturbed testosterone homeostasis and changed the transcriptional profile of steroidogenic machinery, cAMP/cGMP signalling and adrenergic receptors in Leydig cells of adult rats.Pharmacological doses of testosterone upregulated androgen receptor and 3-Beta-hydroxysteroid dehydrogenase/delta-5-delta-4 isomerase and impaired leydig cells steroidogenesis in adult rats.Repeated immobilization stress disturbed steroidogenic machinery and stimulated the expression of cAMP signaling elements and adrenergic receptors in Leydig cells.Phosphodiesterase Inhibitors (PDE Inhibitors) and Male Reproduction.Melatonin promotes development of haploid germ cells from early developing spermatogenic cells of Suffolk sheep under in vitro condition.In vivo blockade of α1-adrenergic receptors mitigates stress-disturbed cAMP and cGMP signaling in Leydig cells.Effects of chronic administration of the phosphodiesterase inhibitor vardenafil on serum levels of adrenal and testicular steroids in men with type 2 diabetes mellitus.Effects of taking tadalafil 5 mg once daily on erectile function and total testosterone levels in patients with metabolic syndrome.Sustained in vivo blockade of α₁-adrenergic receptors prevented some of stress-triggered effects on steroidogenic machinery in Leydig cells.Aging has the opposite effect on cAMP and cGMP circadian variations in rat Leydig cells.Numeric and volumetric changes in Leydig cells during aging of rats.Integrated bioinformatic analysis unveils significant genes and pathways in the pathogenesis of supratentorial primitive neuroectodermal tumor.Mixed testicular atrophy related to atherosclerosis: first lessons from the ApoE(-/-)/ LDL receptor(-/-) double knockout mouse model.Sildenafil increases serum testosterone levels by a direct action on the testes.
P2860
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P2860
Sildenafil treatment in vivo stimulates Leydig cell steroidogenesis via the cAMP/cGMP signaling pathway.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
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2010年论文
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name
Sildenafil treatment in vivo s ...... e cAMP/cGMP signaling pathway.
@en
Sildenafil treatment in vivo s ...... e cAMP/cGMP signaling pathway.
@nl
type
label
Sildenafil treatment in vivo s ...... e cAMP/cGMP signaling pathway.
@en
Sildenafil treatment in vivo s ...... e cAMP/cGMP signaling pathway.
@nl
prefLabel
Sildenafil treatment in vivo s ...... e cAMP/cGMP signaling pathway.
@en
Sildenafil treatment in vivo s ...... e cAMP/cGMP signaling pathway.
@nl
P2093
P2860
P1476
Sildenafil treatment in vivo s ...... e cAMP/cGMP signaling pathway.
@en
P2093
Marija M Janjic
Natasa J Stojkov
Silvana A Andric
Tatjana S Kostic
P2860
P304
P356
10.1152/AJPENDO.00337.2010
P577
2010-07-27T00:00:00Z