White-to-brown metabolic conversion of human adipocytes by JAK inhibition.
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Unlock the Thermogenic Potential of Adipose Tissue: Pharmacological Modulation and Implications for Treatment of Diabetes and ObesityType I/II cytokines, JAKs, and new strategies for treating autoimmune diseasesBioengineering Beige Adipose Tissue TherapeuticsLkb1 controls brown adipose tissue growth and thermogenesis by regulating the intracellular localization of CRTC3Accelerating glioblastoma drug discovery: Convergence of patient-derived models, genome editing and phenotypic screeningWnt inhibition enhances browning of mouse primary white adipocytesLoss of pericyte smoothened activity in mice with genetic deficiency of leptin.Pathway reporter genes define molecular phenotypes of human cellsTargeting senescent cells enhances adipogenesis and metabolic function in old ageImmune regulation of metabolic homeostasis in health and disease.The Thermogenic Circuit: Regulators of Thermogenic Competency and DifferentiationFibroblast dynamics as an in vitro screening platform for anti-fibrotic drugs in primary myelofibrosis.Minireview: Genome Editing of Human Pluripotent Stem Cells for Modeling Metabolic Disease.JAK2 inhibitor combined with DC-activated AFP-specific T-cells enhances antitumor function in a Fas/FasL signal-independent pathway.Trisomy 21 consistently activates the interferon response.Brown adipogenic potential of brown adipocytes and peri-renal adipocytes from human embryo.Metabolic programming of a beige adipocyte phenotype by genisteinJAK2 promotes brown adipose tissue function and is required for diet- and cold-induced thermogenesis in mice.Opportunities and challenges in three-dimensional brown adipogenesis of stem cells.The JAK/STAT pathway in obesity and diabetes.Adipocyte STAT5 deficiency promotes adiposity and impairs lipid mobilisation in mice.Commentary: Heart Failure with Preserved Ejection Fraction Induces Beiging in Adipose Tissue.Chemical transdifferentiation: closer to regenerative medicine.PRDM16 represses the type I interferon response in adipocytes to promote mitochondrial and thermogenic programing.Benefit and Risk of Tofacitinib in the Treatment of Rheumatoid Arthritis: A Focus on Herpes Zoster.Tofacitinib for the treatment of psoriasis.Browning of White Fat: Novel Insight Into Factors, Mechanisms, and Therapeutics.Identification and Optimization of Combinatorial Glucose Metabolism Inhibitors in Hepatocellular Carcinomas.A systems perspective on brown adipogenesis and metabolic activation.Pharmacologic activation of estrogen receptor β increases mitochondrial function, energy expenditure, and brown adipose tissue.Adipose tissue-derived stromal vascular fraction in regenerative medicine: a brief review on biology and translation.Induction of thermogenic adipocytes: molecular targets and thermogenic small molecules.Sustained zero-order delivery of GC-1 from a nanochannel membrane device alleviates metabolic syndrome.Using Thermogenic Beige Cells to Identify Biologically Active Small Molecules and Peptides.Human germline hedgehog pathway mutations predispose to fatty liver.Foxc2 coordinates inflammation and browning of white adipose by leptin-STAT3-PRDM16 signal in mice.Functional Human Beige Adipocytes From Induced Pluripotent Stem Cells.Zooming in on adipocytes: High and deep.GSK3 is a negative regulator of the thermogenic program in brown adipocytes.[Leukocyte count of puerperal sows].
P2860
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P2860
White-to-brown metabolic conversion of human adipocytes by JAK inhibition.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
White-to-brown metabolic conversion of human adipocytes by JAK inhibition.
@en
White-to-brown metabolic conversion of human adipocytes by JAK inhibition.
@nl
type
label
White-to-brown metabolic conversion of human adipocytes by JAK inhibition.
@en
White-to-brown metabolic conversion of human adipocytes by JAK inhibition.
@nl
prefLabel
White-to-brown metabolic conversion of human adipocytes by JAK inhibition.
@en
White-to-brown metabolic conversion of human adipocytes by JAK inhibition.
@nl
P2093
P2860
P356
P1433
P1476
White-to-brown metabolic conversion of human adipocytes by JAK inhibition.
@en
P2093
Anna Kiialainen
Annie Moisan
Carolyn S Hudak
Chad A Cowan
Claas A Meyer
Hoa Hue Truong
Jitao David Zhang
Kurt E Amrein
Martin Ebeling
P2860
P2888
P356
10.1038/NCB3075
P577
2014-12-08T00:00:00Z