White-to-brown metabolic conversion of human adipocytes by JAK inhibition. - Wikidata - wikimedia - TriplyDB

White-to-brown metabolic conversion of human adipocytes by JAK inhibition.

White-to-brown metabolic conversion of human adipocytes by JAK inhibition.

http://www.wikidata.org/entity/Q42972519

about

Unlock the Thermogenic Potential of Adipose Tissue: Pharmacological Modulation and Implications for Treatment of Diabetes and Obesity Type I/II cytokines, JAKs, and new strategies for treating autoimmune diseases Bioengineering Beige Adipose Tissue Therapeutics Lkb1 controls brown adipose tissue growth and thermogenesis by regulating the intracellular localization of CRTC3 Accelerating glioblastoma drug discovery: Convergence of patient-derived models, genome editing and phenotypic screening Wnt inhibition enhances browning of mouse primary white adipocytes Loss of pericyte smoothened activity in mice with genetic deficiency of leptin.Pathway reporter genes define molecular phenotypes of human cells Targeting senescent cells enhances adipogenesis and metabolic function in old age Immune regulation of metabolic homeostasis in health and disease.The Thermogenic Circuit: Regulators of Thermogenic Competency and Differentiation Fibroblast dynamics as an in vitro screening platform for anti-fibrotic drugs in primary myelofibrosis.Minireview: Genome Editing of Human Pluripotent Stem Cells for Modeling Metabolic Disease.JAK2 inhibitor combined with DC-activated AFP-specific T-cells enhances antitumor function in a Fas/FasL signal-independent pathway.Trisomy 21 consistently activates the interferon response.Brown adipogenic potential of brown adipocytes and peri-renal adipocytes from human embryo.Metabolic programming of a beige adipocyte phenotype by genistein JAK2 promotes brown adipose tissue function and is required for diet- and cold-induced thermogenesis in mice.Opportunities and challenges in three-dimensional brown adipogenesis of stem cells.The JAK/STAT pathway in obesity and diabetes.Adipocyte STAT5 deficiency promotes adiposity and impairs lipid mobilisation in mice.Commentary: Heart Failure with Preserved Ejection Fraction Induces Beiging in Adipose Tissue.Chemical transdifferentiation: closer to regenerative medicine.PRDM16 represses the type I interferon response in adipocytes to promote mitochondrial and thermogenic programing.Benefit and Risk of Tofacitinib in the Treatment of Rheumatoid Arthritis: A Focus on Herpes Zoster.Tofacitinib for the treatment of psoriasis.Browning of White Fat: Novel Insight Into Factors, Mechanisms, and Therapeutics.Identification and Optimization of Combinatorial Glucose Metabolism Inhibitors in Hepatocellular Carcinomas.A systems perspective on brown adipogenesis and metabolic activation.Pharmacologic activation of estrogen receptor β increases mitochondrial function, energy expenditure, and brown adipose tissue.Adipose tissue-derived stromal vascular fraction in regenerative medicine: a brief review on biology and translation.Induction of thermogenic adipocytes: molecular targets and thermogenic small molecules.Sustained zero-order delivery of GC-1 from a nanochannel membrane device alleviates metabolic syndrome.Using Thermogenic Beige Cells to Identify Biologically Active Small Molecules and Peptides.Human germline hedgehog pathway mutations predispose to fatty liver.Foxc2 coordinates inflammation and browning of white adipose by leptin-STAT3-PRDM16 signal in mice.Functional Human Beige Adipocytes From Induced Pluripotent Stem Cells.Zooming in on adipocytes: High and deep.GSK3 is a negative regulator of the thermogenic program in brown adipocytes.[Leukocyte count of puerperal sows].

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P2860

White-to-brown metabolic conversion of human adipocytes by JAK inhibition.

http://www.wikidata.org/entity/Q42972519

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2014年论文

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2014年论文

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2014年论文

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name

White-to-brown metabolic conversion of human adipocytes by JAK inhibition.

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White-to-brown metabolic conversion of human adipocytes by JAK inhibition.

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type

label

White-to-brown metabolic conversion of human adipocytes by JAK inhibition.

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White-to-brown metabolic conversion of human adipocytes by JAK inhibition.

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prefLabel

White-to-brown metabolic conversion of human adipocytes by JAK inhibition.

@en

White-to-brown metabolic conversion of human adipocytes by JAK inhibition.

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Nature Cell Biology

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White-to-brown metabolic conversion of human adipocytes by JAK inhibition.

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P2093

Anna Kiialainen

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Annie Moisan

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Carolyn S Hudak

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Chad A Cowan

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Claas A Meyer

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Fang Xia

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Hoa Hue Truong

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Jitao David Zhang

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Kurt E Amrein

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Martin Ebeling

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P2860

Identification and importance of brown adipose tissue in adult humans

Advanced Assay Development Guidelines for Image-Based High Content Screening and Analysis

A road map for those who don't know JAK-STAT

Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human

Cold acclimation recruits human brown fat and increases nonshivering thermogenesis.

Tyk2 and Stat3 regulate brown adipose tissue differentiation and obesity

beta-Adrenergic activation of p38 MAP kinase in adipocytes: cAMP induction of the uncoupling protein 1 (UCP1) gene requires p38 MAP kinase.

p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene

Activation of PPAR gamma induces profound multilocularization of adipocytes in adult mouse white adipose tissues.

The role of JAK-STAT signaling in adipose tissue function.

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57-67

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10.1038/NCB3075

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1

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17

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Michael Prummer

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2014-12-08T00:00:00Z

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269413285

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25487280

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4276482

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