Ca2+/calmodulin modulates TRPV1 activation by capsaicin.
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International Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel familyTRPV1: a target for next generation analgesicsTRPV1: on the road to pain reliefPhysiology and pharmacology of the vanilloid receptorFunctional interactions between A' helices in the C-linker of open CNG channels.TRPV1: A Target for Rational Drug DesignCapsaicin: Current Understanding of Its Mechanisms and Therapy of Pain and Other Pre-Clinical and Clinical UsesRegulation of transient receptor potential channels by the phospholipase C pathwayFunctionally important amino acid residues in the transient receptor potential vanilloid 1 (TRPV1) ion channel--an overview of the current mutational dataTRP channels and analgesiaDistinct properties of Ca 2+ –calmodulin binding to N- and C-terminal regulatory regions of the TRPV1 channelStructural and Biochemical Consequences of Disease-Causing Mutations in the Ankyrin Repeat Domain of the Human TRPV4 ChannelCompetitive inhibition of TRPV1-calmodulin interaction by vanilloidsCalmodulin and S100A1 protein interact with N terminus of TRPM3 channelThe vanilloid receptor TRPV1 is activated and sensitized by local anesthetics in rodent sensory neuronsExploring functional roles of TRPV1 intracellular domains with unstructured peptide-insertion screeningAKAP150-mediated TRPV1 sensitization is disrupted by calcium/calmodulin.Determinants of molecular specificity in phosphoinositide regulation. Phosphatidylinositol (4,5)-bisphosphate (PI(4,5)P2) is the endogenous lipid regulating TRPV1.Anti-calmodulins and tricyclic adjuvants in pain therapy block the TRPV1 channelInteraction with phosphoinositides confers adaptation onto the TRPV1 pain receptor.Interdomain interactions control Ca2+-dependent potentiation in the cation channel TRPV4Role of myeloid-derived suppressor cells in amelioration of experimental autoimmune hepatitis following activation of TRPV1 receptors by cannabidiolLinoleic acid inhibits TRP channels with intrinsic voltage sensitivity: Implications on the mechanism of linoleic acid action.Structure-functional intimacies of transient receptor potential channels.Tolerability of NGX-4010, a capsaicin 8% dermal patch, following pretreatment with lidocaine 2.5%/prilocaine 2.5% cream in patients with post-herpetic neuralgia.Ca2+-dependent desensitization of TRPV2 channels is mediated by hydrolysis of phosphatidylinositol 4,5-bisphosphate.Integrative binding sites within intracellular termini of TRPV1 receptor.The effects of intraarticular resiniferatoxin in experimental knee-joint arthritis.PP2B/calcineurin-mediated desensitization of TRPV1 does not require AKAP150.Localization of the PIP2 sensor of TRPV1 ion channelsSubgroup-elimination transcriptomics identifies signaling proteins that define subclasses of TRPV1-positive neurons and a novel paracrine circuit.IP3 receptor binds to and sensitizes TRPV4 channel to osmotic stimuli via a calmodulin-binding site.Constitutive activity of TRP channels methods for measuring the activity and its outcome.Activity and Ca²⁺ regulate the mobility of TRPV1 channels in the plasma membrane of sensory neurons.A combined coarse-grained and all-atom simulation of TRPV1 channel gating and heat activationTRPM8 acute desensitization is mediated by calmodulin and requires PIP(2): distinction from tachyphylaxis.A channelopathy mechanism revealed by direct calmodulin activation of TrpV4.TRP channels and Ca2+ signaling.Insights on TRP channels from in vivo studies in Drosophila.Anti-nociceptive and desensitizing effects of olvanil on capsaicin-induced thermal hyperalgesia in the rat.
P2860
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P2860
Ca2+/calmodulin modulates TRPV1 activation by capsaicin.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Ca2+/calmodulin modulates TRPV1 activation by capsaicin.
@en
Ca2+/calmodulin modulates TRPV1 activation by capsaicin.
@nl
type
label
Ca2+/calmodulin modulates TRPV1 activation by capsaicin.
@en
Ca2+/calmodulin modulates TRPV1 activation by capsaicin.
@nl
prefLabel
Ca2+/calmodulin modulates TRPV1 activation by capsaicin.
@en
Ca2+/calmodulin modulates TRPV1 activation by capsaicin.
@nl
P2093
P2860
P356
P1476
Ca2+/calmodulin modulates TRPV1 activation by capsaicin
@en
P2093
Ariela Gordon-Shaag
Mika Munari
Sharona E Gordon
P2860
P356
10.1085/JGP.200308906
P50
P577
2004-01-01T00:00:00Z