Patient autoantibodies deplete postsynaptic muscle-specific kinase leading to disassembly of the ACh receptor scaffold and myasthenia gravis in mice.
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Pathogenesis of myasthenia gravis: update on disease types, models, and mechanismsAnimal models of myasthenia gravis: utility and limitationsThe role of muscle-specific tyrosine kinase (MuSK) and mystery of MuSK myasthenia gravisPyridostigmine but not 3,4-diaminopyridine exacerbates ACh receptor loss and myasthenia induced in mice by muscle-specific kinase autoantibodyEffects of the ß2-adrenoceptor agonist, albuterol, in a mouse model of anti-MuSK myasthenia gravisAltered active zones, vesicle pools, nerve terminal conductivity, and morphology during experimental MuSK myasthenia gravisThe neuromuscular junction: measuring synapse size, fragmentation and changes in synaptic protein density using confocal fluorescence microscopy.Intercommunication between the neuroendocrine and immune systems: focus on myasthenia gravis.Anti-MuSK autoantibodies block binding of collagen Q to MuSK.Collagen Q and anti-MuSK autoantibody competitively suppress agrin/LRP4/MuSK signaling.Forced expression of muscle specific kinase slows postsynaptic acetylcholine receptor loss in a mouse model of MuSK myasthenia gravisMaternal autoantibodies in autismMuSK myasthenia gravis IgG4 disrupts the interaction of LRP4 with MuSK but both IgG4 and IgG1-3 can disperse preformed agrin-independent AChR clusters.Antibodies against low-density lipoprotein receptor-related protein 4 induce myasthenia gravis.MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4.Acute severe animal model of anti-muscle-specific kinase myasthenia: combined postsynaptic and presynaptic changes.Pathogenic IgG4 subclass autoantibodies in MuSK myasthenia gravis.Pathogenic immune mechanisms at the neuromuscular synapse: the role of specific antibody-binding epitopes in myasthenia gravis.Animal models of antimuscle-specific kinase myasthenia.Role of occlusion in masseter muscle acetylcholine receptor clustering.Muscle-specific kinase antibodies: a novel cause of peripheral nerve hyperexcitability?Anti-MuSK antibody myasthenia gravis: clinical findings and response to treatment in two large cohorts.The mouse passive-transfer model of MuSK myasthenia gravis: disrupted MuSK signaling causes synapse failure.IgG4-mediated autoimmune diseases: a niche of antibody-mediated disorders.Agrin-LRP4-MuSK signaling as a therapeutic target for myasthenia gravis and other neuromuscular disorders.A New Classification System for IgG4 Autoantibodies.Cannabinoid-induced increase of quantal size and enhanced neuromuscular transmission.Muscle-specific kinase (MuSK) autoantibodies suppress the MuSK pathway and ACh receptor retention at the mouse neuromuscular junction.
P2860
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P2860
Patient autoantibodies deplete postsynaptic muscle-specific kinase leading to disassembly of the ACh receptor scaffold and myasthenia gravis in mice.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Patient autoantibodies deplete ...... and myasthenia gravis in mice.
@en
Patient autoantibodies deplete ...... and myasthenia gravis in mice.
@nl
type
label
Patient autoantibodies deplete ...... and myasthenia gravis in mice.
@en
Patient autoantibodies deplete ...... and myasthenia gravis in mice.
@nl
prefLabel
Patient autoantibodies deplete ...... and myasthenia gravis in mice.
@en
Patient autoantibodies deplete ...... and myasthenia gravis in mice.
@nl
P2093
P2860
P50
P1476
Patient autoantibodies deplete ...... and myasthenia gravis in mice
@en
P2093
N Ghazanfari
O L Gervásio
P2860
P304
P356
10.1113/JPHYSIOL.2010.190298
P407
P577
2010-07-05T00:00:00Z