Regulation of hepatitis C virus polyprotein processing by signal peptidase involves structural determinants at the p7 sequence junctions.
about
Hepatitis C virus proteinsStructural and Functional Properties of the Hepatitis C Virus p7 ViroporinComplete translation of the hepatitis C virus genome in vitro: membranes play a critical role in the maturation of all virus proteins except for NS3.Signal peptide cleavage and internal targeting signals direct the hepatitis C virus p7 protein to distinct intracellular membranes.Construction and characterization of infectious intragenotypic and intergenotypic hepatitis C virus chimerasCompensatory Mutations in E1, p7, NS2, and NS3 Enhance Yields of Cell Culture-Infectious Intergenotypic Chimeric Hepatitis C VirusHepatitis C Virus p7 and NS2 Proteins Are Essential for Production of Infectious VirusAlanine Scanning of the Hepatitis C Virus Core Protein Reveals Numerous Residues Essential for Production of Infectious VirusStructural and Functional Characterization of Nonstructural Protein 2 for Its Role in Hepatitis C Virus AssemblyArchitects of assembly: roles of Flaviviridae non-structural proteins in virion morphogenesisCharacterization of Determinants Important for Hepatitis C Virus p7 Function in Morphogenesis by Using trans-ComplementationNMR Structure and Ion Channel Activity of the p7 Protein from Hepatitis C VirusStructural and Functional Studies of Nonstructural Protein 2 of the Hepatitis C Virus Reveal Its Key Role as Organizer of Virion AssemblyStructure and Activity of Streptococcus pyogenes SipA: A Signal Peptidase-Like Protein Essential for Pilus PolymerisationThe hepatitis C virus E1 glycoprotein undergoes productive folding but accelerated degradation when expressed as an individual subunit in CHO cells.The subcellular localization of the hepatitis C virus non-structural protein NS2 is regulated by an ion channel-independent function of the p7 proteinDetergent-resistant membrane association of NS2 and E2 during hepatitis C virus replicationThe N-terminal Helical Region of the Hepatitis C Virus p7 Ion Channel Protein Is Critical for Infectious Virus Production.Intramolecular regulation of the sequence-specific mRNA interferase activity of MazF fused to a MazE fragment with a linker cleavable by specific proteasesHepatitis C virus nonstructural protein 5B is involved in virus morphogenesis.Host proteolytic activity is necessary for infectious bursal disease virus capsid protein assembly.Subcellular localization and function of an epitope-tagged p7 viroporin in hepatitis C virus-producing cellsIon Channel Function and Cross-Species Determinants in Viral Assembly of Nonprimate Hepacivirus p7Efficiency of E2-p7 processing modulates production of infectious hepatitis C virusPost-translational modifications of hepatitis C viral proteins and their biological significance.Hepatitis C virus p7: molecular function and importance in hepatitis C virus life cycle and potential antiviral target.Hepatitis C virus p7-a viroporin crucial for virus assembly and an emerging target for antiviral therapy."Too little, too late?" Will inhibitors of the hepatitis C virus p7 ion channel ever be used in the clinic?Chimeric GB virus B genomes containing hepatitis C virus p7 are infectious in vivo.Classical swine fever virus nonstructural protein p7 modulates infectious virus productionThe amino-terminus of the hepatitis C virus (HCV) p7 viroporin and its cleavage from glycoprotein E2-p7 precursor determine specific infectivity and secretion levels of HCV particle types.Activities of Thrombin and Factor Xa are essential for replication of Hepatitis E virus and are possibly implicated in the ORF1 polyprotein processing.Hepatitis C virus: Morphogenesis, infection and therapy.Toxin-Antitoxin Systems in Bacteria and Archaea
P2860
Q24563969-558F5F97-1C2D-405A-BEB9-72179890D81DQ26799884-156067C0-6514-4656-B062-6CEB19A192E1Q27469609-48756FA8-1401-4D65-A0A3-57888B60A412Q27472765-87E1A214-8820-4C0C-8B6E-189D4D58C3B5Q27473179-44A66355-F538-4245-8029-50D9A94F1F71Q27478033-14B0AEFD-309A-43DA-A2AC-A6EE8CAE31FCQ27481018-2563C52A-6866-4503-BA9B-5372CFAF9B50Q27481484-B6A37BED-ABA6-4440-AE6D-B4987AEB5D62Q27488261-463625C8-428F-49B4-829C-521F404CC1A8Q27490193-BAFCE3F4-967A-46F5-B2E9-CA4F9797772BQ27490303-F89A984D-2A9F-4380-94F6-7A616E683E70Q27663637-8C2096A3-4EEC-40F3-9EF9-D49F3A137C64Q27666400-EC2A2099-DB71-4CC8-8559-9BF2BFA7CB68Q27684249-C10FE631-85CC-4630-8693-9F9491914963Q34000089-0D9CD95A-DD93-46A2-A700-9F8BA9B2A797Q35097566-2EDA4313-F04D-4C9A-B1B1-33C2B48E33B3Q35641053-13CDA02B-2DBA-4FB6-A7B9-1CB4EACEB340Q35847084-A6BFD632-D71F-46D5-9F8D-DDD8D055D607Q35940944-03FF35EC-4B62-474C-9520-4C3C2900F2F9Q35943750-02AD47C5-2F3C-4E40-A0BD-29C3F8F44AEEQ36098010-3F36316A-A7C8-4ABF-BFC6-851C25C36589Q36559831-B547A266-C4A5-4999-A865-D0D654BF2C05Q36878871-1B78897F-46ED-433C-990A-03A8A893A5DEQ37252600-08170CCD-AE1B-4851-A4AB-A13AC13AD7CBQ37408926-E7355640-A9CE-441E-853B-ED8586F13DD5Q37860404-5B1E53D4-0DB8-4DD6-B20D-FDE7D86335C7Q38615924-3CB1ED27-BCBF-4566-8A96-C95978BEB346Q39077941-4CECF753-4DDA-4F6E-8FA6-ABA3819DD141Q39930810-6E9B639B-E74A-4E9D-BA17-AF22A70B2ED7Q41918673-D6FD3E34-40FB-4056-A7EF-6AB10C38F0FAQ47280477-52BCC5DF-12D6-4194-9B73-4E69745CB594Q47555798-6D5C8DA3-2CA6-41C7-9085-7D5003027BC7Q52661702-ADFCFC77-1643-4F98-998C-DE430294D39EQ57987392-1C8CCF4A-A7F8-4796-9F33-A07748FD8A37
P2860
Regulation of hepatitis C virus polyprotein processing by signal peptidase involves structural determinants at the p7 sequence junctions.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Regulation of hepatitis C viru ...... at the p7 sequence junctions.
@en
Regulation of hepatitis C viru ...... at the p7 sequence junctions.
@nl
type
label
Regulation of hepatitis C viru ...... at the p7 sequence junctions.
@en
Regulation of hepatitis C viru ...... at the p7 sequence junctions.
@nl
prefLabel
Regulation of hepatitis C viru ...... at the p7 sequence junctions.
@en
Regulation of hepatitis C viru ...... at the p7 sequence junctions.
@nl
P2093
P50
P356
P1476
Regulation of hepatitis C viru ...... at the p7 sequence junctions.
@en
P2093
Bénédicte Brulin
François Penin
Séverine Carrère-Kremer
P304
41384-41392
P356
10.1074/JBC.M406315200
P407
P577
2004-07-07T00:00:00Z