Functional architecture of HCV IRES domain II stabilized by divalent metal ions in the crystal and in solution.
about
Small molecules targeting viral RNAThe structures of nonprotein-coding RNAs that drive internal ribosome entry site functionTargeted inhibition of the hepatitis C internal ribosomal entry site genomic RNA with oligonucleotide conjugatesStructure and function of HCV IRES domainsConformational inhibition of the hepatitis C virus internal ribosome entry site RNAInhibitor-induced structural change in the HCV IRES domain IIa RNASelf-assembling RNA squareStructure-function studies of nucleocytoplasmic transport of retroviral genomic RNA by mRNA export factor TAPViral IRES RNA structures and ribosome interactionsStructural and energetic analysis of 2-aminobenzimidazole inhibitors in complex with the hepatitis C virus IRES RNA using molecular dynamics simulations.2-Aminobenzoxazole ligands of the hepatitis C virus internal ribosome entry siteRegulation of PKR by HCV IRES RNA: importance of domain II and NS5AToward a structural understanding of IRES RNA functionHepatitis C virus translation inhibitors targeting the internal ribosomal entry site.RNA structural elements of hepatitis C virus controlling viral RNA translation and the implications for viral pathogenesis.Functional conservation despite structural divergence in ligand-responsive RNA switches.Ligand-responsive RNA mechanical switches.Crystal-Structure-Guided Design of Self-Assembling RNA Nanotriangles.HCV IRES domain IIb affects the configuration of coding RNA in the 40S subunit's decoding groove.Structure of a hepatitis C virus RNA domain in complex with a translation inhibitor reveals a binding mode reminiscent of riboswitchesConformational flexibility of viral RNA switches studied by FRET.A modular approach to synthetic RNA binders of the hepatitis C virus internal ribosome entry site.Screening for inhibitors of the hepatitis C virus internal ribosome entry site RNA.IRES-induced conformational changes in the ribosome and the mechanism of translation initiation by internal ribosomal entry.Coarse grained models reveal essential contributions of topological constraints to the conformational free energy of RNA bulges.Hepatitis C viral protein translation: mechanisms and implications in developing antivirals.Understanding the potential of hepatitis C virus internal ribosome entry site domains to modulate translation initiation via their structure and function.The Emerging Role of RNA as a Therapeutic Target for Small Molecules.Locking out viral replication.Computational study of the structural plasticity and the ligand binding affinity of the IRES subdomain IIa.A structural module in RNase P expands the variety of RNA kinks.Viral internal ribosomal entry sites: four classes for one goal.De novo design of an RNA tile that self-assembles into a homo-octameric nanoprism.In vivo production of RNA nanostructures via programmed folding of single-stranded RNAs.
P2860
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P2860
Functional architecture of HCV IRES domain II stabilized by divalent metal ions in the crystal and in solution.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Functional architecture of HCV ...... n the crystal and in solution.
@en
Functional architecture of HCV ...... n the crystal and in solution.
@nl
type
label
Functional architecture of HCV ...... n the crystal and in solution.
@en
Functional architecture of HCV ...... n the crystal and in solution.
@nl
prefLabel
Functional architecture of HCV ...... n the crystal and in solution.
@en
Functional architecture of HCV ...... n the crystal and in solution.
@nl
P2093
P356
P1476
Functional architecture of HCV ...... n the crystal and in solution.
@en
P2093
Hillary Johnston-Cox
Sergey M Dibrov
Thomas Hermann
Yi-Hsin Weng
P304
P356
10.1002/ANIE.200603807
P407
P577
2007-01-01T00:00:00Z