Immunomodulatory effects of diclofenac in leukocytes through the targeting of Kv1.3 voltage-dependent potassium channels.
about
Lymphocyte Kv1.3-channels in the pathogenesis of chronic obstructive pulmonary disease: novel therapeutic implications of targeting the channels by commonly used drugsUnconventional EGF-induced ERK1/2-mediated Kv1.3 endocytosisKCNE gene expression is dependent on the proliferation and mode of activation of leukocytesInhibition of immune responses and related proteins in Rhamdia quelen exposed to diclofenac.Potent suppression of Kv1.3 potassium channel and IL-2 secretion by diphenyl phosphine oxide-1 in human T cells.Role of diclofenac in the prevention of postpericardiotomy syndrome after cardiac surgerySelective inhibition of CCR7(-) effector memory T cell activation by a novel peptide targeting Kv1.3 channel in a rat experimental autoimmune encephalomyelitis modelInhibition of Kv channel expression by NSAIDs depolarizes membrane potential and inhibits cell migration by disrupting calpain signalingLovastatin blocks Kv1.3 channel in human T cells: a new mechanism to explain its immunomodulatory propertiesInsights into the effects of diclofenac and other non-steroidal anti-inflammatory agents on ion channels.The voltage-dependent K(+) channels Kv1.3 and Kv1.5 in human cancer.Potassium channels in cell cycle and cell proliferation.Physiological significance of delayed rectifier K(+) channels (Kv1.3) expressed in T lymphocytes and their pathological significance in chronic kidney disease.Roles of lymphocyte kv1.3-channels in the pathogenesis of renal diseases and novel therapeutic implications of targeting the channels.Usefulness of targeting lymphocyte Kv1.3-channels in the treatment of respiratory diseases.The voltage-gated potassium channel Kv1.3 is a promising multitherapeutic target against human pathologies.Kv1.3 channel blockade enhances the phagocytic function of RAW264.7 macrophages.Emerging role for the voltage-dependent K+ channel Kv1.5 in B-lymphocyte physiology: expression associated with human lymphoma malignancy.Diclofenac inhibits lactate formation and efficiently counteracts local immune suppression in a murine glioma model.Targeting Kv1.3 channels to reduce white matter pathology after traumatic brain injury.Kv1.5 in the immune system: the good, the bad, or the ugly?Neglected Necrotizing Fasciitis - A Rare Complication of Spinal Anaesthesia.Voltage-dependent biphasic effects of chloroquine on delayed rectifier K(+)-channel currents in murine thymocytes.Overexpression of Delayed Rectifier K(+) Channels Promotes In situ Proliferation of Leukocytes in Rat Kidneys with Advanced Chronic Renal Failure.Embryonic exposure to diclofenac disturbs actin organization and leads to myofibril misalignment.Diabetes Mellitus and Ischemic Heart Disease: The Role of Ion Channels.Regulation of K+ Channels by Cholesterol-Rich Membrane Domains in the Immune SystemEffect of aspirin on cell growth of human MG-63 osteosarcoma line
P2860
Q28069399-3C5CE89C-E6C9-489B-9CD9-94904A5EDC1BQ30009074-475693AD-AE08-4B30-833B-86007FB18A6BQ30540173-6DBAA060-1965-4366-A7D7-670B213D1165Q31155555-265F3E35-4CE3-4A76-A7EC-FB8554E15FC0Q34746164-120B022B-2CCE-4BE2-A624-7DFA71DF7B38Q35822070-61BEDB78-D1DA-431B-A3D3-1B2D6BA48339Q36215897-30F4CB00-3A31-4E5B-9A74-245BC400E887Q36307625-83E1E09A-83FE-4265-B640-C4B1958F4A87Q36330011-6FFA8607-360F-40F3-A052-E06BEC0DD8C6Q38040134-6C8EEC4D-89CA-49B5-A967-861C25BD8308Q38153378-B1834DB8-63BB-464B-8A1C-EE6144A0522CQ38184978-067A8568-4B27-4CCE-AC4E-0B13597ED421Q38237328-916889BD-3750-4BEA-B38A-401F53F05647Q38417868-FC59AF03-C43F-4B1B-AD38-EBA7A998ECC3Q38553215-3CFB5C69-E236-4885-AE75-96F1615DE57AQ38658556-D8AEF32C-0E2B-49C3-92A2-02551E830FBEQ38836515-78EB1043-E2B9-4743-9428-7358CC3ADC03Q39126925-2A4D3B1D-77B9-46FD-8938-1C575BC5850AQ39321386-D3002A15-42BE-46F8-BC06-555DD706A608Q41484523-48B47D55-7698-4753-A246-7449D7C446A3Q41788733-DF15F6FC-DDF4-4B11-810F-9843D18E3AC6Q41879306-6C60BD02-E8D3-4FF9-B5E1-B4649AA57190Q41930362-73E43072-3149-450F-A9D4-627744F65F22Q42186528-49F29D93-13CB-4FC8-925E-A5FC342A4550Q44387103-D49BE9EB-B9A6-4423-8682-587E740F31E4Q52357267-7A1E3E3F-05EB-4D23-A80E-AC072B5E787CQ58212931-47185789-F279-4712-9882-4EA2CECB0418Q58915078-B0B5A341-DA8B-498A-9737-C3A8718CAA12
P2860
Immunomodulatory effects of diclofenac in leukocytes through the targeting of Kv1.3 voltage-dependent potassium channels.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh-hant
name
Immunomodulatory effects of di ...... -dependent potassium channels.
@en
Immunomodulatory effects of di ...... -dependent potassium channels.
@nl
type
label
Immunomodulatory effects of di ...... -dependent potassium channels.
@en
Immunomodulatory effects of di ...... -dependent potassium channels.
@nl
prefLabel
Immunomodulatory effects of di ...... -dependent potassium channels.
@en
Immunomodulatory effects of di ...... -dependent potassium channels.
@nl
P2093
P50
P1476
Immunomodulatory effects of di ...... -dependent potassium channels.
@en
P2093
Joanna Bielańska
Miren David
Núria Villalonga
Teresa González
P304
P356
10.1016/J.BCP.2010.05.012
P407
P577
2010-05-19T00:00:00Z